Epidemiological profile of tuberculosis cases with HIV coinfection in Porto Alegre city, Brazil

Abstract

Objective: To describe and compare the epidemiological profile of cases of tuberculosis and HIV coinfection of the District Administration Health Units of Porto Alegre, Brazil, from 2009 to 2013. Method: Retrospective cohort with data from national health information systems. Sociodemographic, clinical and follow-up variables were investigated through association tests. Results: 2,419 cases of tuberculosis and HIV coinfection were reported, with a mean age of 38 ± 9.91 years, predominantly white and with up to 7 years of study. The comparison between the District Administration Health Units was significant in terms of race/color (p<0.001), gender (p<0.001), schooling (p<0.004), age (p<0.003), place of origin (p<0.001), (p<0.001), alcoholism (p<0.001), indication and performance of Directly Observed Therapy (p<0.001), closure (p<0.001). Conclusion: Socioeconomic and treatment variables influence the occurrence of coinfection in different areas of Porto Alegre, reinforcing that the sum of different factors explains the indicators of the disease.

Efficacy, effectiveness, and safety of integrase inhibitors in the treatment of HIV/AIDS in patients with tuberculosis: systematic review and meta-analysis

“…The population of coinfected patients included in the studies consisted mainly of young adults, mostly men, from countries in different geographic regions and with different levels of socioeconomic development. These findings corroborate previous studies that investigated coinfection (Lemos et al 2016;Rosetto et al 2019, Mariano, Magnabosco & Orfão,2021 and identified that in both TB and HIV/AIDS infection, the male population is the most vulnerable and prevalent for coinfection, with a higher concentration in the economically active age group (15-50 years) (Lemos et al 2016;Rosetto et al 2019, Mariano, Magnabosco & Orfão,2021.…”

Casos de coinfecção por tuberculose e HIV no estado de Goiás, no período de 2008 a 2019

“…Quanto a frequência da coinfecção em relação ao sexo do infectado, foi observada uma taxa mais elevada nos indivíduos do sexo masculino (81,5%). Em estudos realizados não só em Goiás 14 , e em outras regiões do país, como Rio Grande do Norte 15 , Porto Alegre 16 , Piauí 17 e Distrito Federal 18 foi verificada uma prevalência maior neste mesmo grupo, corroborando assim nossos achados. Isso provavelmente se deve ao fato do homem não possuir o hábito de procurar os serviços de saúde 19 .…”

Anais do I Congresso Online em Doenças Negligenciadas e Emergentes

“…No intuito de evitar interações medicamentosas e diminuir a toxicidade, pode-se substituir a rifampicina pela rifabutina. No entanto, essa mudança ocasiona o aumento no custo do tratamento, acarretando uma distribuição limitada à população, dificultando ainda mais o acesso e a adesão (ROSSETTO, et al, 2019).…”