Enhanced multifunctionality of CuO nanoparticles synthesized using aqueous leaf extract of Vernonia amygdalina plant

Murthy, H. C. Ananda; Desalegn, Tegene; Tan, Kar Ban; Ghotekar, Suresh; Alam, Mir Waqas; Balachandran, R.; Chan, Kah‐Yoong; Sanaulla, P. F.; Kumar, Manjeet; Ravikumar, C.R.

doi:10.1016/j.rechem.2021.100141

Cited by 32 publications

(3 citation statements)

References 43 publications

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“…Green synthesis offers the benefits of being non-toxic and eco-friendly, while being highly cost effective. It employs the use of sunlight, irradiation, and microorganisms such as fungi, algae, and bacteria for the preparation of NPs used both intracellularly and extracellularly [35]. Various types of gold NPs, such as gold nanospheres, nanorods and nanostars, can be prepared using this technique.…”

Section: Bio-synthesis Methodsmentioning

confidence: 99%

Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology

et al. 2022

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The difficulty of achieving targeted drug delivery following administration of currently marketed anticancer therapeutics is a still a concern. Metallic nanoparticles (NPs) developed through nanotechnology breakthroughs appear to be promising in this regard. Research studies pertaining to gold NPs have indicated their promising applicability in cancer diagnosis, drug delivery and therapy. These NPs have also recently paved the path for precise drug delivery and site-specific targeting. Our review paper thus highlights the scope and impact of biogenetically generated gold nanoparticles (NPs) in cancer therapy. In a critical, constructive, and methodical manner, we compare the advantages offered by gold NPs over other metal NPs. Moreover, we also focus on novel ‘greener’ strategies that have been recently explored for the preparation of gold NPs and shed light on the disadvantages of conventional NP synthesis routes. Future prospects pertaining to the use of gold NPs in oncotherapy and domains that require further investigation are also addressed.

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Section: Bio-synthesis Methodsmentioning

confidence: 99%

Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology

et al. 2022

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“…This process is considered non-toxic, environmentally friendly and cost-effective. Green synthesis involves the production of NPs internally and externally using sunlight, electricity and organisms such as fungi, algae and bacteria ( 129 ). This technique allows for the production of various types of gold NPs, including nanospheres, nanorods, and nanostars.…”

Section: Role Of Nanotherapeutic In the Management Of Crcmentioning

confidence: 99%

Recent advances in nanomedicine preparative methods and their therapeutic potential for colorectal cancer: a critical review

Jain

Bhattacharya

2023

Front. Oncol.

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Colorectal cancer (CRC) is a prevalent malignancy that affects a large percentage of the global population. The conventional treatments for CRC have a number of limitations. Nanoparticles have emerged as a promising cancer treatment method due to their ability to directly target cancer cells and regulate drug release, thereby enhancing therapeutic efficacy and minimizing side effects. This compilation examines the use of nanoparticles as drug delivery systems for CRC treatment. Different nanomaterials can be used to administer anticancer drugs, including polymeric nanoparticles, gold nanoparticles, liposomes, and solid lipid nanoparticles. In addition, we discuss recent developments in nanoparticle preparation techniques, such as solvent evaporation, salting-out, ion gelation, and nanoprecipitation. These methods have demonstrated high efficacy in penetrating epithelial cells, a prerequisite for effective drug delivery. This article focuses on the various targeting mechanisms utilized by CRC-targeted nanoparticles and their recent advancements in this field. In addition, the review offers descriptive information regarding numerous nano-preparative procedures for colorectal cancer treatments. We also discuss the outlook for innovative therapeutic techniques in the management of CRC, including the potential application of nanoparticles for targeted drug delivery. The review concludes with a discussion of current nanotechnology patents and clinical studies used to target and diagnose CRC. The results of this investigation suggest that nanoparticles have great potential as a method of drug delivery for the treatment of colorectal cancer.

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“…The inhibition zones were in range from 7.4 to 22.3 mm for E. coli , S. typhi , S. aureus and V. cholerae . Recently, Ananda Murthy et al ( 2021 ) used V. amygdalina leaves as the main raw material to synthesize CuO nanoparticles for antibacterial performance. The results showed that S. aureus , E. coli and P. aeruginosa had an inhibition zone of about 12 mm while that of E. aerogenes was 15 mm.…”

Section: Applications Of Nanoparticles Synthesized From Plantsmentioning

confidence: 99%

Formation, antimicrobial activity, and biomedical performance of plant-based nanoparticles: a review

Nguyen

et al. 2022

Environ Chem Lett

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Because many engineered nanoparticles are toxic, there is a need for methods to fabricate safe nanoparticles such as plant-based nanoparticles. Indeed, plant extracts contain flavonoids, amino acids, proteins, polysaccharides, enzymes, polyphenols, steroids, and reducing sugars that facilitate the reduction, formation, and stabilization of nanoparticles. Moreover, synthesizing nanoparticles from plant extracts is fast, safe, and cost-effective because it does not consume much energy, and non-toxic derivatives are generated. These nanoparticles have diverse and unique properties of interest for applications in many fields. Here, we review the synthesis of metal/metal oxide nanoparticles with plant extracts. These nanoparticles display antibacterial, antifungal, anticancer, and antioxidant properties. Plant-based nanoparticles are also useful for medical diagnosis and drug delivery.

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Enhanced multifunctionality of CuO nanoparticles synthesized using aqueous leaf extract of Vernonia amygdalina plant

Cited by 32 publications

References 43 publications

Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology

Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology

Recent advances in nanomedicine preparative methods and their therapeutic potential for colorectal cancer: a critical review

Formation, antimicrobial activity, and biomedical performance of plant-based nanoparticles: a review

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