Ellipsoidal porous patch with anisotropic cell inducing ability for inhibiting skin scar formation

Weng, Wanqing; Chi, Junjie; Wang, Xiaocheng; Shi, Ke‐Qing; Ye, Fangfu; Zhao, Yuanjin

doi:10.1016/j.engreg.2022.06.003

Cited by 10 publications

(9 citation statements)

References 37 publications

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Section: Photonic Crystal Structural Porosity and Interconnectivity A...mentioning

confidence: 99%

“…[375] Anisotropic IO structures, deformed by stretching an axis in a particular direction, have been utilized to direct the orientation of cell growth for controlling nerve cell growth [376] and preventing skin scar formation. [377] The macroporous structure of IO configurations has also attracted some attention for its potential to act as a separation or filtering membrane. Specifically, 3DOM IO structures with highly interconnected and regular pore sizes have been explored as microfiltration [378] or ultrafiltration [379] separation membranes.…”

Section: Photonic Crystal Structural Porosity and Interconnectivity A...mentioning

confidence: 99%

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Many Facets of Photonic Crystals: From Optics and Sensors to Energy Storage and Photocatalysis

Lonergan

O’Dwyer

2022

Adv Materials Technologies

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b) Biomimetic inspired and durable bone implant in sheep based on nacre structures, nacre is marked as N in the radiograph [48] and optical microscope image. [49] Reproduced with permission. [48] Copyright 1999, Elsevier. Adapted with permission. [49] Copyright 2005, Elsevier. c) Nanosized bumps on the lotus leaf [25] and the curved fibrous microstructure of the silver ragwort leaf. [41] Adapted with permission. [25] Copyright 2011, Beilstein Institute for the Advancement of Chemical Sciences. Adapted with permission. [41] Copyright 2011, Royal Society of Chemistry. d) Leaf-inspired polystyrene fibers coated with silica nanoparticles to create a polystyrene fiber mat with excellent hydrophobic properties. [41] Adapted with permission. [41] Copyright 2011, Royal Society of Chemistry. e) Cone-shaped micro and nanostructures found on moth eyes [50,51] create an anti-reflective effect. Adapted with permission. [50] Copyright 2008, SPIE. Adapted with permission. [51] Copyright 2018, Nature. f) Moth eye inspired TiO 2 -PMMA nanocomposite structural film [52] showing improved anti-reflective properties (right disc) versus a non-structured PMMA film (left disc). Adapted with permission. [52]

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Section: Photonic Crystal Structural Porosity and Interconnectivity A...mentioning

confidence: 99%

Section: Photonic Crystal Structural Porosity and Interconnectivity A...mentioning

confidence: 99%

Many Facets of Photonic Crystals: From Optics and Sensors to Energy Storage and Photocatalysis

Lonergan

O’Dwyer

2022

Adv Materials Technologies

View full text Add to dashboard Cite

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“…Therefore, it is urgent to explore smart and effective antibacterial strategies for making revised use of antibiotics, at which concertation at the site is decreased with time after application that may allow for new bacterial proliferation. One of the most promising options is a smart wound dressing capable of delivering the payload to the site in a controllable and sustained manner [ [6] , [7] , [8] ].…”

Section: Introductionmentioning

confidence: 99%

Phase-change composite filled natural nanotubes in hydrogel promote wound healing under photothermally triggered drug release

Hao

et al. 2023

Bioactive Materials

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“…[11] As a result, the application of antibiotics and growth factors is one of the most important means after wound creation. Many platforms have been established to deliver antibacterial agents or bioactive molecules to the wound bed to accelerate chronic wound curing, such as bactericidal dressings, [12,13] electrostatic fibers, [14][15][16][17] skin patches, [18,19] antiinfective microspheres, [20] and functional hydrogels. [21][22][23][24][25] Despite some achievements, conventional formulations for chronic wound treatment have drawbacks.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional MOF‐Based Microneedle Patch With Synergistic Chemo‐Photodynamic Antibacterial Effect and Sustained Release of Growth Factor for Chronic Wound Healing

Zeng

Wang

Lou

et al. 2023

Adv Healthcare Materials

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Chronic wound healing is a major challenge in biomedicine. Conventional therapies are usually associated with poor drug permeability, low bioavailability, risk of antimicrobial resistance, and require frequent administration. Therefore, a novel formulation with reduced antibiotic dosage, improved drug delivery efficiency, and low application frequency is of remarkable interest for chronic wound healing. Herein, a multifunctional microneedle (MN) patch is presented to achieve rapid wound healing via efficient chemo-photodynamic antibacterial effect and sustained release of growth factors at the wound bed. When the MN patch pierces the skin, MN tips carrying both low dosage of antibiotics and bioactive small molecule-encapsulated metal-organic frameworks (MOFs) rapidly dissolve and subsequently deliver the payloads to the wound. Upon light irradiation, MOF-based nanoparticles robustly convert O 2 into 1 O 2 , which acts synergistically with chemotherapy to remove pathogenic bacteria from the wound, exhibiting excellent chemo-photodynamic antibacterial performance with a tenfold reduction in the required antibiotic amount. The nanoparticles can achieve a continuous release of growth factors in the wound tissue, promoting the formation of epithelial tissue and neovascularization, thereby further accelerating chronic wound healing. Collectively, the designed multifunctional MOF-based MN patches offer a simple, safe, and effective alternative for chronic wound management.

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Ellipsoidal porous patch with anisotropic cell inducing ability for inhibiting skin scar formation

Cited by 10 publications

References 37 publications

Many Facets of Photonic Crystals: From Optics and Sensors to Energy Storage and Photocatalysis

Many Facets of Photonic Crystals: From Optics and Sensors to Energy Storage and Photocatalysis

Phase-change composite filled natural nanotubes in hydrogel promote wound healing under photothermally triggered drug release

Multifunctional MOF‐Based Microneedle Patch With Synergistic Chemo‐Photodynamic Antibacterial Effect and Sustained Release of Growth Factor for Chronic Wound Healing

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