Electrochemical paper based cancer biosensor using iron oxide nanoparticles decorated PEDOT:PSS

Kumar, Saurabh; Umar, M. Sarosh; Saifi, Anas; Kumar, Suveen; Augustine, Shine; Srivastava, Saurabh; Malhotra, Bansi D.

doi:10.1016/j.aca.2018.12.053

Cited by 106 publications

(46 citation statements)

References 37 publications

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“…The one-step immobilization technique has helped to produce functionalized films possessing an optimal working pH close to that of free enzymes to conserve their conformation and microenvironment. PPY, PEDOT: PSS, and polyaminobenzoic acid (PABA) are some common polymers used in biosensor fabrication [54][55][56][57]. A biosensor for 17β-estradiol detection is fabricated based on a benzothiadiazole derivative of EDOT [58].…”

Section: Retention Of Biorecognition Molecules By Conducting Polymersmentioning

confidence: 99%

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Luong

Narayan

Solanki

et al. 2020

JFB

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Conducting polymers (CPs) have been at the center of research owing to their metal-like electrochemical properties and polymer-like dispersion nature. CPs and their composites serve as ideal functional materials for diversified biomedical applications like drug delivery, tissue engineering, and diagnostics. There have also been numerous biosensing platforms based on polyaniline (PANI), polypyrrole (PPY), polythiophene (PTP), and their composites. Based on their unique properties and extensive use in biosensing matrices, updated information on novel CPs and their role is appealing. This review focuses on the properties and performance of biosensing matrices based on CPs reported in the last three years. The salient features of CPs like PANI, PPY, PTP, and their composites with nanoparticles, carbon materials, etc. are outlined along with respective examples. A description of mediator conjugated biosensor designs and enzymeless CPs based glucose sensing has also been included. The future research trends with required improvements to improve the analytical performance of CP-biosensing devices have also been addressed.

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Section: Retention Of Biorecognition Molecules By Conducting Polymersmentioning

confidence: 99%

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Luong

Narayan

Solanki

et al. 2020

JFB

Self Cite

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“…With the progress in the fields of nanoscience and nanotechnology, a wide range of nanomaterials with excellent chemical, physical, and mechanical properties have been developed and adapted in biosensing platforms. They include several types of nanomaterials such as noble metals [75], metal oxides [76], metal chalcogenides [77], magnetic nanoparticles (NPs) [78], carbon-based nanomaterials [79], conductive polymers [80], etc. Among them, metal nanostructures have been attractive in the design of highly sensitive electrochemical biosensors.…”

Section: Nanobioengineered Electrochemical Biosensorsmentioning

confidence: 99%

Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers

et al. 2020

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The accurate determination of specific tumor markers associated with cancer with non-invasive or minimally invasive procedures is the most promising approach to improve the long-term survival of cancer patients and fight against the high incidence and mortality of this disease. Quantification of biomarkers at different stages of the disease can lead to an appropriate and instantaneous therapeutic action. In this context, the determination of biomarkers by electrochemical biosensors is at the forefront of cancer diagnosis research because of their unique features such as their versatility, fast response, accurate quantification, and amenability for multiplexing and miniaturization. In this review, after briefly discussing the relevant aspects and current challenges in the determination of colorectal tumor markers, it will critically summarize the development of electrochemical biosensors to date to this aim, highlighting the enormous potential of these devices to be incorporated into the clinical practice. Finally, it will focus on the remaining challenges and opportunities to bring electrochemical biosensors to the point-of-care testing.

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“…These changes in sensing parameter relied on selection of the dopant (nanomaterials) and solvent. Conductivity of CP was found to be increased by two orders of magnitude (10 −4 to 10 −2 Scm −1 ) by treatment with different solvents like ethylene glycol (EG), formic acid, and DMSO 23a,27,70. Whereas nanomaterials such as RGO, CNT, and n Fe 2 O 3 can be utilized to obtain improved electrochemical properties, signal stability, and enhanced mass loading of a bioreceptor.…”

Section: Application Of Nanomaterial‐modified Cpmentioning

confidence: 99%

Nanomaterial‐Modified Conducting Paper: Fabrication, Properties, and Emerging Biomedical Applications

et al. 2019

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The emerging demand for wearable, lightweight portable devices has led to the development of new materials for flexible electronics using non‐rigid substrates. In this context, nanomaterial‐modified conducting paper (CP) represents a new concept that utilizes paper as a functional part in various devices. Paper has drawn significant interest among the research community because it is ubiquitous, cheap, and environmentally friendly. This review provides information on the basic characteristics of paper and its functionalization with nanomaterials, methodology for device fabrication, and their various applications. It also highlights some of the exciting applications of CP in point‐of‐care diagnostics for biomedical applications. Furthermore, recent challenges and opportunities in paper‐based devices are summarized.

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Electrochemical paper based cancer biosensor using iron oxide nanoparticles decorated PEDOT:PSS

Cited by 106 publications

References 37 publications

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers

Nanomaterial‐Modified Conducting Paper: Fabrication, Properties, and Emerging Biomedical Applications

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