El uso clínico de aloinjertos de piel humana criopreservados con fines de trasplante

Martínez‐Flores, Francisco; Chacón-Gómez, María; Madinaveitia-Villanueva, Juan Antonio; Barrera-López, Araceli; Aguirre-Cruz, Lucinda; Querevalú-Murillo, Walter

doi:10.1016/j.circir.2015.06.004

Cited by 5 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Алгоритм подготовки, хранения и использования аллотрансплантатов не отличается сложностью. Трансплантаты кожи сохраняют путем лиофилизации или замораживания [21,22]. Все трансплантаты кожи условно можно разделить на две группы: с сохраненной жизнеспособностью тканей и лишенную жизнеспособных клеток.…”

Section: производство лиофилизированных аллотрансплантатов кожиunclassified

“…Одним из способов консервирования аллотрансплантатов кожи, позволяющих хранить их длительное время при комнатной температуре, является лиофилизация [21,22] [26,27].…”

Section: производство лиофилизированных аллотрансплантатов кожиunclassified

See 1 more Smart Citation

Use of cadaver skin in the treatment of wounds

Sachkov¹,

Borovkova²,

Жиркова³

et al. 2018

Transplantologiâ (Mosk.)

View full text Add to dashboard Cite

The article has analyzed the world experience and main trends in the preparation of cadaveric skin for use in the treatment of patients with wounds of various etiologies. The history of the question is described from the first attempts of transplantation of the native skin to the creation of specialized banks of allogenic decellularized tissue grafts. Presented are the modern approaches of donor material conservation, specifically, to the principle and topical question: whether the viability of the cells should be preserved in the graft, or it is more efficient to transplant the skin devoid of cellular elements. The advantages and disadvantages of lyophilized grafts have been described, namely the possibility of longterm storage, but loss of elasticity, after rehydration. The methods of cryoconservation of cutaneous allografts, their properties, and acceptable methods of sterilization have been discussed. A perspective technology of graft decellularization has been assessed and the methodologies of their manufacturing have briefly been presented.

show abstract

Section: производство лиофилизированных аллотрансплантатов кожиunclassified

Use of cadaver skin in the treatment of wounds

Sachkov¹,

Borovkova²,

Жиркова³

et al. 2018

Transplantologiâ (Mosk.)

View full text Add to dashboard Cite

show abstract

“…As published earlier, most allogeneic skin grafts are usually obtained from cadaveric donors sharing all of the disadvantages of allogeneic transplants such as disease transmission, immunogenicity, rejection and secondary infection 7,12,13 . Skin allografts are currently commercially available through skin and tissue banks all over the world to enable a better availability and to ensure patients' safety and high product quality 8,14 …”

Section: Introductionmentioning

confidence: 99%

“…7,12,13 Skin allografts are currently commercially available through skin and tissue banks all over the world to enable a better availability and to ensure patients' safety and high product quality. 8,14 The history of skin tissue banking dates back to the 1990s. [15][16][17] Harvesting and culture procedures aim to ensure that the largest part of the donated skin is transferred into viable skin allografts for transplantation purposes.…”

Section: Introductionmentioning

confidence: 99%

Organization of Hannover Skin Bank: Sterile culture and procurement protocols for viable cryopreserved allogeneic skin grafts of living donors

Schlottmann,

Strauß,

Ziesing

et al. 2023

International Wound Journal

View full text Add to dashboard Cite

Preserved allogeneic donor skin still represents one of the gold standard therapies in temporary wound coverage in severely burned patients or chronic wounds. Allogeneic skin grafts are currently commercially available as cryo‐ or glycerol‐preserved allografts through skin tissue banks all over the world. Most of the skin tissue banks rely on human cadaveric skin donations. Due to the chronic shortage of human allogeneic transplants, such as skin, and increasing costs in the procurement of allografts from other skin tissue banks, Hannover Medical School has been building up its own skin tissue bank based on allogeneic skin grafts from living donors who underwent surgical treatment (i.e., body‐contouring procedures, such as abdominioplasties). This article presents procedures and protocols for the procurement and processing of allogeneic skin grafts according to national legislation and European regulations and guidelines. Beside protocols, initial microbiological data regarding the sterility of the harvested grafts are presented. The results currently form the basis for further investigations as well as clinical applications. In summary, a microbiological testing and acceptance procedure is presented that ensures adequate patient safety and skin viability.

show abstract

Experience in use of biological coatings in complex treatment of extensive burn wounds

Borisov

Sachkov

Kaplunova

et al. 2020

Medicinskij alfavit

View full text Add to dashboard Cite

The article presents the experience of successful surgical treatment of a patient with a severe burn injury using biological wound coatings with cadaveric skin grafts and dermal matrix afer wound debridement. Each of the presented biological coatings was evaluated on the basis of their clinical effectiveness (general condition of the patient, stage of the wound-healing process) and the results of microscopic examination of histological material during preparation of wounds for autotransplantation.

show abstract

El uso clínico de aloinjertos de piel humana criopreservados con fines de trasplante

Abstract: It is proposed to consider recipient's blood group as allocation criteria to assign tissue; and use human skin allografts on patiens affected with burns over 30% of body surface (according the "rule of the 9").

Cited by 5 publications

References 13 publications

Use of cadaver skin in the treatment of wounds

Use of cadaver skin in the treatment of wounds

Organization of Hannover Skin Bank: Sterile culture and procurement protocols for viable cryopreserved allogeneic skin grafts of living donors

Experience in use of biological coatings in complex treatment of extensive burn wounds

Contact Info

Product

Resources

About