Efficacy and safety of Danggui Buxue Decoction in combination with western medicine treatment of anemia for renal anemia: a systematic review and meta-analysis

Abstract

Conclusions: Danggui Buxue Decoction in combination with conventional western medicine (CWM) for renal anemia might be superior to CWM alone and there was no adverse event in the experimental group, it might be more effective when the ratio of Radix Astragali to Radix Angelicae Sinensis was 5:1. However, the quality of included studies was not high, and less attention was paid to the safety, high quality randomized controlled trials are needed to further confirm the findings.

Repressed Exercise-Induced Hepcidin Levels after Danggui Buxue Tang Supplementation in Male Recreational Runners

“…According to the Taiwan Herbal Pharmacopeia [ 56 ], such a dose has been recorded in the ancient book Nei Wai Shang Bian Huo Lun, with the effects of alleviating qi weakness, blood deficiency, and fatigue. A meta-analysis study [ 57 ] reviewed the current clinical practices and the safety of administering DBT in renal anaemic patients of either gender. In most of the included studies, the patients were aged 40–60 years and they were administered daily AM and AS at the respective weights of 30 g and 6 g or more.…”

Effectiveness of Chinese Herbal Medicine Combined with Antibiotics for Extensively Drug-Resistant Enterobacteria and Nonfermentative Bacteria Infection: Real-Life Experience in a Retrospective Cohort

“…Dang gui and Huang qi are often prescribed together, the two herbs compose a formula, Dangguibuxue decoction, which is the most frequently used TCM formula with a function of tonifying qi and enriching blood [ 35 , 36 ]. This remedy has been used for various diseases for more than 800 years in China [ 37 ] and shows broad-spectrum bioactivities such as enhancing bone regeneration [ 38 ], attenuating pulmonary fibrosis [ 39 ], stimulating proliferation of T-lymphocytes proliferation [ 40 ], and alleviating renal damage and diabetic nephropathy [ 41 ].…”

Knowledge Mapping of Angelica sinensis (Oliv.) Diels (Danggui) Research: A Scientometric Study

“…At the same time, in recent years, a new research method of TCM, NP (or systems pharmacology) (Xie et al, 2018) and has been widely accepted and employed in recent years to investigate the mechanisms of TCM for many chronic complex conditions at the molecular, cellular, and system level, such as cardiovascular diseases, diabetes mellitus, and tumors (Li et al, 2017;Lu et al, 2019). Meanwhile, the concept of EBM has also been introduced into TCM (Luo et al, 2012;Zhao et al, 2017;. All of these developments are important for the modernization and internationalization of TCM, and also provide a huge potential for the development of AS and herbs research.…”

“…Modern pharmacological studies have revealed that compounds identified and isolated from AS have a variety of pharmacological actions, including anti-inflammatory, anti-tumor, immunostimulatory, hormone-regulation, anti-hepatotoxic, neuroprotective, antiaging and anti-cardiovascular diseases effects (Ooi and Liu, 2000;Chao and Lin, 2011). AS can be used alone, but is more often prescribed in combination with other medicines in a formulation, such as Siwu (SW) (Hu and Guo, 2017;Feng and Shi, 2019) and Danggui buxue (DGBX) decoration (Lin et al, 2017;Zhao et al, 2017). For example, SW consists of four medicines: (1) AS, (2) Chuanxiong [CX, Conioselinum anthriscoides 'Chuanxiong' (Apiaceae)], (3) Baishao [BS, Paeonia lactiflora Pall.…”

“…(Orobanchaceae)], which are used to treat constipation and anemia (Hu and Guo, 2017;Feng and Shi, 2019). The other one common formulation, DGBX, consists of two herbs, AS and Huangqi [HQ, Astragalus mongholicus Bunge (Fabaceae)], and is used to treat anemia and menopausal symptoms, among other diseases (Lin et al, 2017;Zhao et al, 2017).…”