Effects of topical application of Curcuma longa extract in the treatment of early periodontal diseases

Sharma, Vikrant; Kalsi, Devinder Singh

doi:10.4103/0976-4003.191725

Cited by 10 publications

(4 citation statements)

References 2 publications

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“…37 Several recent studies have shown that curcuma extract can be a good adjunct for scaling and root planning. 19,20,26,27,32,33 Commonly known Babul (Aracia Arabica) has cyanogenic glycosides and numerous enzymes like oxidases, peroxidases and pectinases. Its bark contains tanins which are known to have not just analegesic, anti-inflammatory properties but also antimicrobial properties.…”

Section: Discussionmentioning

confidence: 99%

Herbal medicine as adjunct in periodontal therapies- A review of clinical trials in past decade

Abdelmagyd

Shetty

Al-Ahmari

2019

Journal of Oral Biology and Craniofacial Research

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The aim of this paper was to analyze the literature published in the research related to herbal medicine as adjunct in periodontal therapies. An internet search using search engines-Google, Researchgate and PubMed was carried out. The keywords used for search were-periodontal therapy, adjunct, herbal, and periodontitis. Full text articles of the articles were collected from the year 2007-2017. The data available from the clinical trials the journal articles were analyzed and presented in both tabular and descriptive patterns. The herbs frequently tested used for treatment of periodontitis are Acacia catechu, Aloe vera, Azadirachta indica, Glycyrrhiza glabra, Cinnamomum zeylanicum, Allium sativum, Propolis, Mikania laevigata, Mikania glomerate, Droserapeltata, Helichrysumitalicum, Coptidis rhizome, Piper cubeba, Azadirachta indica, Syzygium Aromaticum and Tea tree oil. 8 Besides the above mentioned herbal remedies a number of other herbal based products are also undergoing

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Section: Discussionmentioning

confidence: 99%

Herbal medicine as adjunct in periodontal therapies- A review of clinical trials in past decade

Abdelmagyd

Shetty

Al-Ahmari

2019

Journal of Oral Biology and Craniofacial Research

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“…While the use of systemic medicines against periodontal disease has been shown in several published research with various side effects. 29 Curcumin has been known worldwide for its many health benefits 30 and clinical use of Curcumin as a suitable adjunct in the treatment of periodontitis has been reported by many researchers 31 , 32 , 33 and several others. Therefore, the aim of the current study was to assess the impact of local application of curcumin gels in EPD in rat, depending on its different biological and medicinal properties 34 and to clarify the processes by which this natural plant product acts and compared it with chlorhexidine, the well-known antimicrobial drug.…”

Section: Discussionmentioning

confidence: 99%

Effects of curcumin gel on osteoclastogenic bone markers in experimental periodontitis and alveolar bone loss in wistar rats

Sha

Garib

Azeez

et al. 2021

Journal of Dental Sciences

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Background/purpose Curcumin has anti-inflammatory impacts and was suggested as an inflammatory disease therapy. This study aimed to investigate the implications of curcumin gel on experimental periodontitis (EPD) and alveolar bone loss in rats. Materials and methods In this study, twenty-four male Wistar rats were divided equally into four groups: negative control (with no EPD); positive control (EPD induced around lower centrals without treatment); control-treated group: EPD treated with chlorhexidine; and test EPD group treated with curcumin. After 30 days, the serum concentrations of RANKL and IL-1β were measured via ELISA. All animals were sacrificed, and mandibular central incisors with the periodontium were removed. The lingual probing depth and radiographical alveolar bone loss were measured, then samples processed for routine preparation of H&E stained sections and histologically assessed for counting inflammatory cells, osteoclasts, and PDL width. Results A significant decrease in the inflammatory cells infiltration, probing depth, and osteoclast numbers with the improvement of PDL associated with a reduction in RANKL and IL-1β serum concentration were seen in both EPD treated groups. Conclusion Curcumin is as effective as chlorhexidine in treating experimental periodontitis in rats. It was demonstrated to stop bone destruction related to periodontitis by regulating the RANKL and IL-1β markers level in the blood.

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“…“Curenext” consists of 10 mg/g Curcuma longa L. extract. It is used to treat periodontitis and is also useful in plaque-associated gingivitis [ 49 ]. In a clinical trial done by Kumar et al, herbal dentifrice showed 87–95%, 80–95%, and 70–72% decline in plaque, dental calculus, and gingivitis, respectively, with a treatment of 15 days [ 50 ].…”

Section: Medicinal Plants Used To Treat Gingivitis and Periodontitismentioning

confidence: 99%

Medicinal Plants Used as an Alternative to Treat Gingivitis and Periodontitis

Rani

Singla

Narwal³

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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For various ailments, natural remedies have been traditionally used. To defend against common disorders, medicinal plants are progressively used as nutritional supplements. Gingivitis and periodontitis are widespread and can affect most of the world’s population. Gingivitis is a very common, nondestructive inflammatory disease of gums that causes redness and irritation of the gingiva (gums), but periodontitis causes permanent damage to teeth’ subsidiary structures. Herbal medicines are getting popular for the treatment of such types of disorders due to being economical with their medicinal effectiveness, compatibility, and nontoxicity. Traditional chemical therapies can cause cell toxicity along with their disease-curing effects. In this article, we discussed the medicinal plants that can be used as an alternative for the treatment of gingivitis (early-stage gum disease) and periodontitis (chronic-stage gum disease).

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Effects of topical application of Curcuma longa extract in the treatment of early periodontal diseases

Cited by 10 publications

References 2 publications

Herbal medicine as adjunct in periodontal therapies- A review of clinical trials in past decade

Herbal medicine as adjunct in periodontal therapies- A review of clinical trials in past decade

Effects of curcumin gel on osteoclastogenic bone markers in experimental periodontitis and alveolar bone loss in wistar rats

Medicinal Plants Used as an Alternative to Treat Gingivitis and Periodontitis

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