Effects of selenium and zinc supplementation on cadmium toxicity in broilers

Abstract

Materials and methods Animals, diets, and experimental designOne hundred eighty, as-hatched, 1-day-old, Cobb 500, chickens (broilers) were used in total. Broiler chickens were purchased from a commercial hatchery. There were 4 replicate pens (2 m length × 1 m width) of 3 dietary treatments namely T1, T2, and T3, randomly allocated in the house. Pen was the experimental unit. There were 15 chickens per pen, 60 per treatment. In T1 treatment, Se, Cd, and Zn were added to a basal broiler diet (only naturally present levels of Se, Cd, and Zn) at a level of Abstract: Cadmium (Cd) is a toxic metal regarded as an environmental pollutant. The potential ameliorative effect of simultaneous addition of Se and Zn to broilers against Cd toxicity was examined. A total of 180 as-hatched broilers were used. There were 4 replicate pens of 3 dietary treatments: T1, T2, and T3. In T1, Se, Cd, and Zn were added to a basal diet at 0.3, 0, and 100 ppm, in T2 at 0.3, 50, and 150 ppm, and in T3 at 0.5, 50, and 150 ppm respectively. Selenium, Cd, Ca, Co, Cu, Fe, Li, Mg, Mn, Sb, As, Cr, Pb, Mo, Ni, V, and Zn were determined in breast samples using ICP-MS. Simultaneous addition of Se and Zn to broilers partly ameliorated the negative effects of Cd. The concentrations of Cd, As, and V in breast were significantly affected by the treatments while the concentration of other examined elements remained unaffected.

Innovative and Applied Research in Biology : Proceedings

“…The physiological role of Se in the body relates to activity of glutathionperoxidase (GSH-Px). Se is incorporated in the active site of this enzyme which acts as a free radical scavenger in the body protecting cellular membranes against oxidative stress products (Zoidis et al, 2020). The data of Table 2 showed that intake of diet supplemented with Se prevented Cd-induced disturbance of antioxidant-prooxidant balance in chickens.…”

“…Natural antioxidants including minerals and vitamins play a vital role in the maintenance of antioxidant status in biological systems (Surai, 2019). The protective effect of dietary zinc (Zn) and selenium (Se) against Cd toxicity was studied in broilers (Zoidis et al, 2020). Zn is one of the most important essential trace elements and forms an integral component of several cellular enzymes.…”

The role of natural dietary antioxidants in animals under oxidative stress

“…Natural antioxidants including minerals and vitamins play a vital role in the maintenance of antioxidant status in biological systems (Surai, 2019). The protective effect of dietary zinc (Zn) and selenium (Se) against Cd toxicity was studied in broilers (Zoidis et al, 2020). Zn is one of the most important essential trace elements and forms an integral component of several cellular enzymes.…”

Tannic Acid and Tea Prevents the Accumulation of Lead and Cadmium in the Lungs, Heart and Brain of Adolescent Male Wistar Rats—Possible Therapeutic Option

“…Since it is impossible to eliminate Pb and Cd from food, research is carried out on methods of limiting its absorption by the body. These methods should be easily accessible and uncomplicated [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ]. Foods containing significant amounts of antioxidant components can be used in the daily diet to prevent the dangerous effects of toxic metals on the human body [ 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ].…”