“…The selection of biomarkers used in the present study needed to be suitable for samples obtained by nondestructive sampling and therefore included growth and condition, hematocrit, oxidative stress using the total oxyradical scavenging capacity (TOSC) assay (Winston et al, 1998;Regoli & Winston, 1999), and clastogenic or aneugenic DNA damage using the micronucleus (MN) method (Jaylet et al, 1986). Hematocrit may be affected by a variety of compounds such as metals (Vinodhini & Narayanan, 2009), polychlorinated biphenyls (PCB; Rehulka & Minarik, 2004), and PAH (Jee et al, 2004), and has the potential to indicate the general health level of fish (Blaxhall, 1972;Blaxhall & Daisley, 1973;Mayer et al, 1992). Similarly, fish growth may be affected by several classes of compounds such as dioxins (Elonen et al, 1998), other aryl hydrocarbon receptor (AhR) agonists such as PAH (Jee et al, 2004;Carls et al, 2005Carls et al, , 2007, and compounds with an estrogenic mode of action such as 17α-ethynylestradiol (Van Den Belt et al, 2003).…”