Effects of Dietary Benzo[a]pyrene on Growth and Hematological Parameters in Juvenile Rockfish, Sebastes schlegeli (Hilgendorf)

Abstract

Experiments were conducted to evaluate the effect of dietary benzo[a]pyrene (B[a]P) on the growth and hematological parameters of rockfish, Sebastes schlegeli, after they were fed with subchronic dietary B[a]P for 30 days. The weight growth rate of the rockfish was significantly different from that of the control group at dietary B[a]P concentration of 1.5 and 2.0 mg/kg. Significant reduction in red blood cells, hematocrit, and hemoglobin were observed during 30 days of exposure to the highest concentration. Over 30 days, serum AST increased at a B[a]P concentration of 1.5 mg/kg and LDH increased at a B[a]P concentration of 1.0 mg/kg concentration. However, no changes were observed in ALT, total protein, magnesium or calcium.

The response of thyroid hormones, biochemical and enzymological biomarkers to pyrene exposure in common carp (Cyprinus carpio)

“…In the present study, the plasma levels of AST and ALP were significantly increased after exposure to pyrene. These elevations are common responses to stressors, such as PAHs (Kim et al, 2008;Wegwu and Omeodu, 2010;Salman, 2011;Banaee et al, 2011). AST and ALP are found in the cell cytoplasm and are released into blood vessels when the cells are destroyed or the membrane permeability is increased due to reactive oxygen species (ROS) production by the toxicant (Banaee et al, 2011).…”

“…The plasma biochemical constituents, thyroid hormones, liver function enzymes and ionoregulatory endpoints could also be used as biomarkers to reflect the toxicity of chemicals as they have been frequently used for the toxicity assessment of other PAHs in fish and other animals (Alonso-Alvarez et al, 2007;Kim et al, 2008;Latif et al, 2014;Maria et al, 2002;Okwu et al, 2014;Osman et al, 2009;Salman, 2011;Tintos et al, 2008;Wegwu and Omeodu, 2010). Plasma biochemical indicators and transaminases have been proved to be suitable stress biomarkers in fish because they are inexpensive, less variable, more highly conserved between species and are easy to measure (Naderi et al, 2015;Senthil Kumaran et al, 2011).…”

Trophic contamination by pyrolytic polycyclic aromatic hydrocarbons does not affect aerobic metabolic scope in zebrafish Danio rerio

“…DNA damage; Holth et al , ; Nogueira et al , ) and ontogenic effects (Singh et al , ; Horng et al , ; Incardona et al , ). They have also been found to affect reproduction (Collier et al , ; Seruto et al , ; Vignet et al , 2014 a ), growth (Meador et al , ; Kim et al , ; Vignet et al , 2014 a ), metabolism (Wedemeyer et al , , ; Davoodi & Claireaux, ) and behaviour (Gonzales‐Doncel et al , ; Vignet et al , 2014 b ).…”

Effect of Mercuric Chloride on Some Hematological, Biochemical Parameters in Silver Carp (Hypophthalmichthys Molitrix)

“…Behavioral changes in animal are symptomatic of internal interferences in the body functions, such as disturbances in metabolic routes and ionic imbalance in blood serum (Lewis and Lewis 1971;Shah 2002). Blood indices are more frequently utilized when clinical diagnosis of fish physiology are used to ascertain sublethal and chronic exposure of contaminants (Kim et al, 2008). Fish hematological indices are very susceptible to water contaminants, and its commutation due to the hematological and immunological parameters can be utilized as toxicity indices of xenobiotics (Sancho et al, 2000).…”