Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children

Zhou, Jibo; Li, Weiran

doi:10.4103/ijo.ijo_2886_21

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…And, given the allergic reactions to the eyes, atropine eye drops is often given at a low dose to myopic children [ 11 ]. Studies have shown that 0.01% atropine eye drops (low-dose atropine (LDA)) has no significant adverse effects on children's optical quality, with better therapeutic safety than 0.05% atropine eye drops [ 12 ]. In terms of visual training, virtual reality (VR)-based binocular visual function (BVF) balance training is a kind of stereoscopic perception training for patients by wearing VR visual training glasses.…”

Section: Introductionmentioning

confidence: 99%

Effect of Atropine Eye Drops Combined with VR-Based Binocular Visual Function Balance Training for Prevention and Control of Juvenile Myopia

Shi

2022

Evidence-Based Complementary and Alternative Medicine

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Purpose. This study mainly analyzes the efficacy of 0.01% atropine eye drops (low-dose atropine (LDA)) combined with virtual reality (VR)-based binocular visual function (BVF) balance training in the prevention and control of juvenile myopia. Methods. One hundred and thirty-six juvenile myopia patients admitted between November 2018 to November 2021 were selected, including 76 cases (research group) receiving LDA + VR-based BVF balance training and 60 cases (control group) treated by LDA intervention alone. Visual acuity (VA; naked vision), ocular parameters (pupil diameter (PD), axial length (AXL), and diopter), intraocular pressure (IOP), accommodation facility, clinical efficacy, and incidence of adverse reactions were observed, compared, and analyzed in both groups. Results. After analysis, it was found that the research group showed significantly higher naked vision and PD while statistically lower D after intervention than the corresponding preinterventional parameters than the control group. While AXL showed no statistical difference between the groups and within groups. The IOP also differed insignificantly between groups, but the post-treatment accommodation facility was better in the research group compared with the baseline (before treatment) and control group. In terms of curative effects, an obviously higher total effective rate was determined in the research group. In addition, the two groups showed no significant difference in the incidence of adverse reactions. Conclusions. LDA + VR-based BVF balance training deserves clinical popularization, as it can prevent and control myopia among teenagers, with better adjusting effects on eye function and certain safety.

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Section: Introductionmentioning

confidence: 99%

Effect of Atropine Eye Drops Combined with VR-Based Binocular Visual Function Balance Training for Prevention and Control of Juvenile Myopia

Shi

2022

Evidence-Based Complementary and Alternative Medicine

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Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy

Laspas

Maier

Schuster

et al. 2023

JCM

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The aim of this study was to investigate the effects of atropine on patients’ perception of visual quality after trabeculectomy. Forty patients undergoing standard trabeculectomy with mitomycin C were enrolled in this prospective randomized study. All surgeries were conducted at the ophthalmology department of the University Medical Center of Mainz, Germany. All patients received the same postoperative treatment with ofloxacin and dexamethasone eye drops. Following randomization of patients into two groups of 20 patients, the intervention group also received atropine eye drops three times daily for the first 2 days after surgery to stabilize the anterior chamber. All patients completed a visual quality questionnaire before surgery and 2 and 6 weeks after surgery. Results were compared using the Wilcoxon test. After surgery, there was a reduction in visual quality in all patients. Patients who received atropine eye drops described a greater and longer-lasting reduction in visual quality than those who did not receive atropine eye drops. Trabeculectomy often leads to a transient reduction in visual quality. This reduction was greater in severity and duration in patients who received postoperative atropine eye drops. Thus, unless there is an underlying medical necessity, we would discourage the application of atropine as a standard therapy for trabeculectomy surgery.

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Changing trends in myopia management in pediatric population

Kaur

Gurnani

Porwal

2022

Indian Journal of Ophthalmology

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Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children

Cited by 3 publications

References 22 publications

Effect of Atropine Eye Drops Combined with VR-Based Binocular Visual Function Balance Training for Prevention and Control of Juvenile Myopia

Effect of Atropine Eye Drops Combined with VR-Based Binocular Visual Function Balance Training for Prevention and Control of Juvenile Myopia

Effects of Postoperative Atropine Eye Drops on Visual Quality in Patients Undergoing Trabeculectomy

Changing trends in myopia management in pediatric population

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