Purpose:
The present study was performed to compare the optical quality of the eyes of myopic children before and after treatment with atropine eye drops of different concentrations.
Methods:
In the study population of 71 patients (131 eyes), 34 patients (63 eyes) were given 0.01% atropine eye drops and 37 patients (68 eyes) were given 0.05% atropine eye drops. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs 100%, 20%, and 9%) under different lighting conditions were measured before and after two weeks of atropine treatment.
Results:
After using 0.05% atropine eye drops for two weeks, the Strehl ratio decreased from 0.27 ± 0.07 to 0.23 ± 0.07 (
P
= 0.0026), PVA 20% decreased from 1.15 ± 0.32 to 1.03 ± 0.36 (
P
= 0.0344), and PVA 9% decreased from 0.74 ± 0.23 to 0.64 ± 0.23 (
P
= 0.0073). The OSI was significantly higher after using 0.05% than 0.01% atropine eye drops (
P
= 0.0396), while both the Strehl ratio and PVA 20% were lower after using 0.05% than 0.01% atropine eye drops (
P
= 0.0087 and
P
= 0.0492, respectively).
Conclusion:
The children’s optical quality did not change significantly after using 0.01% atropine eye drops, whereas it decreased after using 0.05% atropine eye drops.
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