Effects of feeding a single or sequence of beta-adrenergic agonists on cull cow meat quality

Weber, Melissa Jean; Dikeman, Michael E.; Jaeger, John R.; Unruh, John A.; Murray, Leigh W.; Houser, T. A.

doi:10.1016/j.meatsci.2012.09.004

Cited by 11 publications

(5 citation statements)

References 34 publications

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“…Nonetheless, its mechanisms have not been studied much [35] during intra uterine life. In addition, the lack of in vivo experimental models has led to the use of in vitro models from primary rat or mice myocyte cultures in the neonatal stage along with its limitations [36], [37].…”

Section: Discussionmentioning

confidence: 99%

Mouse models for the study of postnatal cardiac hypertrophy

Olmo-Turrubiarte

Calzada-Torres

Diaz-Rosas

et al. 2015

IJC Heart & Vasculature

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The main objective of this study was to create a postnatal model for cardiac hypertrophy (CH), in order to explain the mechanisms that are present in childhood cardiac hypertrophy. Five days after implantation, intraperitoneal (IP) isoproterenol (ISO) was injected for 7 days to pregnant female mice. The fetuses were obtained at 15, 17 and 19 dpc from both groups, also newborns (NB), neonates (7–15 days) and young adults (6 weeks of age). Histopathological exams were done on the hearts. Immunohistochemistry and western blot demonstrated GATA4 and PCNA protein expression, qPCR real time the mRNA of adrenergic receptors (α-AR and β-AR), alpha and beta myosins (α-MHC, β-MHC) and GATA4. After the administration of ISO, there was no change in the number of offsprings. We observed significant structural changes in the size of the offspring hearts. Morphometric analysis revealed an increase in the size of the left ventricular wall and interventricular septum (IVS). Histopathological analysis demonstrated loss of cellular compaction and presence of left ventricular small fibrous foci after birth. Adrenergic receptors might be responsible for changing a physiological into a pathological hypertrophy. However GATA4 seemed to be the determining factor in the pathology. A new animal model was established for the study of pathologic CH in early postnatal stages.

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Section: Discussionmentioning

confidence: 99%

Mouse models for the study of postnatal cardiac hypertrophy

Olmo-Turrubiarte

Calzada-Torres

Diaz-Rosas

et al. 2015

IJC Heart & Vasculature

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“…The physiological effect of clenbuterol in dairy cows was limited to the repartitioning effect on body composition with little effect on milk production (Stoffel and Meyer, 1993). Therefore, the primary use in dairy has been in dairy steers (Blum and Flueckiger, 1988;Haneklaus et al, 2011) and cull cows (Weber et al, 2013). The illegal use of clenbuterol, an efficacious but unsafe β-agonist, resulted in the ban of all β-agonists in the European Union (Kuiper et al, 1998).…”

Section: β-Adrenergic Agonistsmentioning

confidence: 99%

A 100-Year Review: Metabolic modifiers in dairy cattle nutrition

McGuffey¹

2017

Journal of Dairy Science

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The first issue of the Journal of Dairy Science in 1917 opened with the text of the speech by Raymond A. Pearson, president of the Iowa State College of Agriculture, at the dedication of the new dairy building at the University of Nebraska (J. Dairy Sci. 1:4-18, 1917). Fittingly, this was the birth of a new research facility and more importantly, the beginning of a new journal devoted to the sciences of milk production and manufacture of products from milk. Metabolic modifiers of dairy cow metabolism enhance, change, or interfere with normal metabolic processes in the ruminant digestive tract or alter postabsorption partitioning of nutrients among body tissues. Papers on metabolic modifiers became more frequent in the journal around 1950. Dairy farming changed radically between 1955 and 1965. Changes in housing and feeding moved more cows outside, and cows and heifers in all stages of lactation, including the dry period, were fed as a single group. Rations became wetter with the shift to corn silage as the major forage in many rations. Liberal grain feeding met the requirements of high-producing cows and increased production per cow but introduced new challenges; for example, managing and feeding cows as a group. These changes led to the introduction of new strategies that identified and expanded the use of metabolic modifiers. Research was directed at characterizing the new problems for the dairy cow created by group feeding. Metabolic modifiers went beyond feeding the cow and included environmental and housing factors and additives to reduce the incidence and severity of many new conditions and pathologies. New collaborations began among dairy cattle specialties that broadened our understanding of the workings of the cow. The Journal of Dairy Science then and now plays an enormously important role in dissemination of the findings of dairy scientists worldwide that address existing and new technologies.

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“…Poderiam-se esperar melhorias na maciez da carne das vacas com maior grau de acabamento, uma vez que essas, possivelmente, foram submetidas a dietas de maior aporte energético, conforme discutido anteriormente, o que, associado à semelhança no tempo de terminação e idade de abate, promoveria tendência de melhorias na maciez. Em virtude disso, aspectos relacionados à modulação de fibras musculares (18) e maior solubilidade do colágeno (19) em vacas que recebem maior aporte energético favorecem melhorias na maciez da carne, principalmente quando a idade de abate das vacas é similar, conforme verificado no presente estudo (60 contra 68 meses, respectivamente, para os graus de acabamento >6 e <6).…”

Section: Resultsunclassified

Características Da Carcaça E Da Carne De Vacas De Descarte Abatidas Com Distintos Pesos E Grau De Acabamento – Abordagem Meta-Analítica

et al. 2015

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Resumo: Objetivou-se, por meio de meta-análise, avaliar as características da carcaça e da carne de vacas de descarte abatidas com diferentes pesos e grau de acabamento. Os tratamentos foram conforme o peso de abate, sendo eles acima de 480,5 kg (Pesada) ou abaixo de 480 kg (Leve) de PV; e grau de acabamento de carcaça, sendo espessura de gordura subcutânea entre 6 a 10 mm (>6) ou entre 3 a 6 mm (<6). O delineamento experimental foi o inteiramente casualizado em arranjo fatorial 2 x 2, duas classes de peso de abate e duas classes de grau de acabamento de carcaça. Para isso, foram avaliados artigos de trabalhos realizados no Brasil que envolveram estudos de carcaças e carne de vacas de biótipo corte, publicados entre janeiro de 2000 a março de 2013, e que pudessem ser acessados pelas plataformas de busca SciELO e Capes. Os artigos foram localizados a partir da combinação das seguintes palavras-chave: carcaça, carne, fêmeas bovinas, novilhas e vacas. O aumento no peso de abate não refletiu no peso de carcaça quente (252,3 contra 233,3 kg). Houve menor rendimento de carcaça quente (52,9 contra 56,9 %) e maior conformação (10,0 contra 8,6 pontos). O maior grau de acabamento influenciou positivamente o marmoreio (8,7 contra 5,4 pontos). A elevação do peso de abate confere carcaças melhor conformadas, sem refletir na qualidade da carne; já a elevação do grau de acabamento, além de 6 mm, altera as características sensoriais da carne.

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Effects of feeding a single or sequence of beta-adrenergic agonists on cull cow meat quality

Cited by 11 publications

References 34 publications

Mouse models for the study of postnatal cardiac hypertrophy

Mouse models for the study of postnatal cardiac hypertrophy

A 100-Year Review: Metabolic modifiers in dairy cattle nutrition

Características Da Carcaça E Da Carne De Vacas De Descarte Abatidas Com Distintos Pesos E Grau De Acabamento – Abordagem Meta-Analítica

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