Effect of strain rate on transient local strain variations in articular cartilage

Komeili, Amin; Abusara, Ziad; Federico, Salvatore; Herzog, Walter

doi:10.1016/j.jmbbm.2019.03.022

Cited by 14 publications

(5 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4c, the mean magnitude of axial strain (normal strain in the z direction) in the central 1 × 1 mm 2 -region (ε zz ) of each layer decreased rapidly from the upper to middle zones and became almost constant over the middle and lower zones. In an earlier study using second harmonic generation microscopy [22], the similar depth-dependent trend of strain was observed in axially compressed AC of the porcine tibial plateau. Such ε zz distribution along the z axis indicates that the compressive deformation is almost limited to the upper layers.…”

Section: Resultssupporting

confidence: 68%

“…Mechanical signals invoked by local AC deformation affect the function of chondrocytes and the pathophysiology of osteoarthritis [23]. Since the local deformation across the AC thickness differed between dynamic and static compression [22], it is significant to extend this method to dynamic viscoelastic testing of AC and characterize local deformation for understanding of health and diseases of AC.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

In-situ deformation imaging of articular cartilage using grating-based phase-contrast X-ray CT at a synchrotron light source

et al. 2022

View full text Add to dashboard Cite

Quantification of deformation behavior of articular cartilage (AC) is crucial for understanding its mechanical function and response to mechanical stimuli. Here, we explored whether grating-based phase-contrast X-ray CT using monochromatic synchrotron light (grating-based msPXCT) enables in-situ quantification of local deformation in AC. Grating-based msPXCT of a porcine AC sample during axial compression test was conducted using a Talbot grating interferometer. Local displacements and strains were computed using a digital volume correlation method. The magnitude of axial strain decreased from the upper to middle sample zones and reached almost constant over the middle-lower zone, consistent with the depth-dependent density increase with compression. Thus, grating-based msPXCT may be suitable for quantitative analysis of AC deformation.

show abstract

Section: Resultssupporting

confidence: 68%

Section: Discussionmentioning

confidence: 99%

In-situ deformation imaging of articular cartilage using grating-based phase-contrast X-ray CT at a synchrotron light source

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The majority of studies of strain in cartilage have taken place in 2D on non-human species 10,19,[35][36][37][38] , with strain observed by slicing the sample and observing strain across the exposed surface. These studies showed the peak strain occurring in the superficial cartilage zone and most showing a non-linear decrease in observed strain through the middle zone to the deep zone.…”

Section: Discussionmentioning

confidence: 99%

High resolution three-dimensional strain measurements in human articular cartilage

Clark

Tavana

Clark

et al. 2021

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

“…By dynamic loading, more uniform deformation across cartilage depth occurs, and this is because of substantial synovial fluid pressure in dynamic loading imposed on the cartilage compared to static loading. Thus, it exemplifies cartilage characteristics in reducing local strains in daily high intense physiological activities [ 51 ].…”

Section: Mechanical Characteristics Of Articular Cartilagementioning

confidence: 99%

Articular and Artificial Cartilage, Characteristics, Properties and Testing Approaches—A Review

2021

View full text Add to dashboard Cite

The design and manufacture of artificial tissue for knee joints have been highlighted recently among researchers which necessitates an apt approach for its assessment. Even though most re-searches have focused on specific mechanical or tribological tests, other aspects have remained underexplored. In this review, elemental keys for design and testing artificial cartilage are dis-cussed and advanced methods addressed. Articular cartilage structure, its compositions in load-bearing and tribological properties of hydrogels, mechanical properties, test approaches and wear mechanisms are discussed. Bilayer hydrogels as a niche in tissue artificialization are presented, and recent gaps are assessed.

show abstract

Effect of strain rate on transient local strain variations in articular cartilage

Cited by 14 publications

References 72 publications

In-situ deformation imaging of articular cartilage using grating-based phase-contrast X-ray CT at a synchrotron light source

In-situ deformation imaging of articular cartilage using grating-based phase-contrast X-ray CT at a synchrotron light source

High resolution three-dimensional strain measurements in human articular cartilage

Articular and Artificial Cartilage, Characteristics, Properties and Testing Approaches—A Review

Contact Info

Product

Resources

About