2011
DOI: 10.1016/j.joen.2010.11.031
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Effect of Novel Chitosan-fluoroaluminosilicate Glass Ionomer Cement with Added Transforming Growth Factor Beta-1 on Pulp Cells

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Cited by 15 publications
(6 citation statements)
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References 28 publications
(28 reference statements)
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“…Based on the results of the current study and other related previous studies, 27,49,50 modification of GIC with CH could be of potential clinical significance in dentistry owing to its proven antibacterial and mechanical reinforcement effects and its ability to carry and sustainably release bioactive molecules and growth factors. However, further research should be extended to study the effect of CH modification of resin-modified glass ionomers and to explore other potential applications of chitosan-modified glass ionomers.…”
Section: Discussionsupporting
confidence: 58%
“…Based on the results of the current study and other related previous studies, 27,49,50 modification of GIC with CH could be of potential clinical significance in dentistry owing to its proven antibacterial and mechanical reinforcement effects and its ability to carry and sustainably release bioactive molecules and growth factors. However, further research should be extended to study the effect of CH modification of resin-modified glass ionomers and to explore other potential applications of chitosan-modified glass ionomers.…”
Section: Discussionsupporting
confidence: 58%
“…Logically, HDACis could be integrated into existing dental restorative materials similar to the way in which other agents have been incorporated with and without the assistance of the material manufacturer (2,26,(36)(37)(38). This approach may be useful for developing a new regenerative restorative material that can be used in direct contact vital pulp treatment and warrants further in vitro studies investigating the physical properties of the integrated material and the stability of HDACi release.…”
Section: Discussionmentioning
confidence: 99%
“…A possible solution to this dilemma is to repair the damaged dentin-pulp complex. Rakkiettiwong et al (21) have demonstrated the retained effect of transforming growth factor beta-1 in a novel material that could be used as a vital pulp therapy material. This growth factor plays a key role in regeneration and repair of the pulp-dentin complex (22).…”
Section: Discussionmentioning
confidence: 99%