Effect of low-level laser therapy (LLLT) on peripheral nerve regeneration using fibrin glue derived from snake venom

Buchaim, Rogério Leone; Andreo, Jesús Carlos; Barraviera, Benedito; Ferreira, Rui Seabra; Buchaim, Daniela Vieira; Rosa, Geraldo Marco; Oliveira, Alexandre Leite Rodrigues de; Rodrigues, Antônio de Castro

doi:10.1016/j.injury.2015.01.031

Cited by 66 publications

(80 citation statements)

References 41 publications

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“…A intervenção pode ser potencializada pela aplicação do LBI, já que ele promove a aceleração da regeneração do nervo, pois age como estimulante celular e modulador do tecido conjuntivo, com uso de LASER infravermelho para favorecimento do trofismo e regeneração do nervo facial 7,27 . No trabalho com Motricidade Orofacial é comum o atendimento a pacientes com disfunções orais resultantes de agressões, tais como o uso de próteses e implantes dentários e de processos de cicatrização tecidual, como nos casos de pós cirurgia de câncer de boca, cirurgia ortognática, cirurgias orais diversas e processos inflamatórios.…”

Section: A) Desordem Temporomandibularunclassified

O uso terapêutico do LASER de Baixa Intensidade (LBI) em algumas patologias e sua relação com a atuação na Fonoaudiologia

Gomes¹,

Schapochnik

2017

Distúrb Comun

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O uso terapêutico do LASER de Baixa Intensidade (LBI) em algumas patologias e sua relação com a atuação na FonoaudiologiaThe therapeutic use of low intensity laser (LLLT) in some diseases and its relation to the performance in speech therapy El uso terapéutico de LÁSER de Baja Intensidad (LBI) en algunas patologías y su relación con la actuación en FonoaudiologíaCristiane Faccio Gomes * Adriana Schapochnik ** ResumoO uso da luz LASER Terapêutico de Baixa Intensidade (LBI) ou Low Level Laser Therapy (LLLT), é multidisciplinar, sendo este utilizado por vários profissionais: médicos, dentistas, fisioterapeutas, enfermeiros, físicos, biólogos, engenheiros, etc. A Fonoaudiologia começa a despertar o interesse em integrar esse grupo de profissionais, sendo um recurso totalmente terapêutico, não invasivo, sem efeitos tóxicos e colaterais que agrega no trabalho terapêutico e estabelece um prognóstico excelente de reabilitação. Por esse motivo, objetivou-se coletar alguns artigos científicos que abordam os fundamentos físicos e bioquímicos da interação da luz do LASER com o tecido biológico vivo e sua aplicabilidade terapêutica nas especialidades da saúde onde encontramos também a atuação da Fonoaudiologia. Para isso foram selecionadas algumas patologias relacionando-as ao uso do LBI: disfunção temporomandibular (DTM), paralisia facial, disfagias por disfunção motora, cicatrização tecidual incluindo as fissuras mamilares, principal responsável pelo abandono do aleitamento materno. No escopo das patologias, será descrita a ação do LASER e seu efeito biomodulador nos processos: inflamatórios, álgicos, cicatriciais, AbstractThe use of Laser Therapy of Low Intensity (LBI) or Low Level Laser Therapy (LLLT), is multidisciplinary, and is used by many professionals: doctors, dentists, physiotherapists, nurses, physicists, biologists, engineers, etc. The Speech Therapy begins to awaken the interest in joining this group of professionals, with a totally therapeutic use, non-invasive, no toxic side effects that adds to the therapeutic work and establishes an excellent rehabilitation prognosis. Therefore, we aimed to collect some research papers that address the physical and biochemical fundamentals of laser light interaction with the living biological tissue and its therapeutic applicability in health specialties where we also find the work of Speech Therapy. For this, we selected some pathology relating the use of LLLT: temporomandibular disorders (TMD), facial palsy, dysphagia by motor dysfunction, tissue healing including the mammillary fissures responsible for abandonment of breastfeeding. In the scope of the conditions, the action of the LASER will be described and its effect on biomodulator processes: inflammatory, nociceptive, scarring, edematous, nerve and muscle repair. We conclude that LLLT is a technological breakthrough and an important tool in different fields, meaning a major evolution in health procedures, even in speech therapy. It is essential to note that the articles present lack of standardization in dosimetry ...

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Section: A) Desordem Temporomandibularunclassified

O uso terapêutico do LASER de Baixa Intensidade (LBI) em algumas patologias e sua relação com a atuação na Fonoaudiologia

Gomes¹,

Schapochnik

2017

Distúrb Comun

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“…The use of the sural nerve in neurotmesis was reported in the experiment by Buchaim et al [10] with a differential: the use of this spinal nerve (sensory) being a donor to the vagus nerve (cranial and mixed), electing the end-to-side technique without an epineural window, also inserting two other components that are gaining prominence in the literature as a repair model in peripheral nerve regeneration, fibrin sealant derived from snake venom and the aid of photobiomodulatory effects of low-level laser therapy.…”

Section: Introductionmentioning

confidence: 97%

“…Fibrin sealant derived from snake venom (Crotalus durissus terrificus) has been highlighted in the international literature [10][11][12][13]. Produced by the research group of the Center for the Study of Venoms and Venomous Animals (CEVAP, UNESP/Botucatu-SP, Brazil), it presents three individual solutions that must be homogenized before application: fibrinogen originated from buffalo blood; calcium chloride and a thrombin-like fraction.…”

Section: Introductionmentioning

confidence: 99%

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Low-Level Laser Therapy (LLLT) Improves the Repair Process of Peripheral Nerve Injuries: A Mini Review

Rosso¹,

Buchaim²,

Rosa³

et al. 2017

Int J Neurorehabilitation Eng

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Purpose: The aim of this study was to perform a mini-review on the effects of low-level laser therapy on nerve regeneration. Methods:In this study, the authors associated the new fibrin sealant derived from snake venom as a method of nerve repair end-to-side. Results and conclusion:The use of fibrin sealant effectively provided an axonal regeneration, and the association with low-level laser therapy elevated this regenerative process, as demonstrated in the morphometric and morphological analyzes.

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“…The biological effects of laser were first studied in 1967 by Inyushin, and the concept of laser therapy began in 1970 when Mester applied it over chronic ulcers to accelerate healing 11 . Since then, it has been used in the treatment of temporomandibular disorders, chronic facial pain, periodontal surgical procedures, tooth hypersensitivity, chronic sinusitis, osseointegration, orthodontic pain reduction, pain after the removal of impacted third molars, sensory aberrations of the inferior alveolar nerve, management of recurrent aphthous stomatitis among others [12][13][14][15][16][17][18] . The biological effects of LLLT are partially produced when its energy is absorbed by the tissues, allowing photons' light to interact with the cellular structure, producing the expected therapeutic effect.…”

Section: Introductionmentioning

confidence: 99%

Clinical efficacy of low level laser therapy in reducing pain and swelling after periapical surgery. A preliminary report.

et al. 2015

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Abstract:The objective of this study was to evaluate the efficacy of the low level laser therapy (LLLT) in postoperative pain and swelling associated with periapical surgery. A double-blind, randomized, controlled clinical trial was carried out in 2 groups of 10 patients each, undergoing periapical surgery. The experimental group was treated with an intraoral application of an 810 nm-GaAsAl-laser, having an output power of 100 mW, with overlapping movements over the wound. In the control group, the same procedure was carried out, without therapeutic laser activation. Postoperative pain, swelling, and rescue medication were registered. The experimental group exhibited a decrease in pain intensity after periapical surgery compared with control group (p<0.05). There was not significant statistical difference between the groups in terms of swelling. Six patients of the control group required rescue medication. The use of LLLT in the postoperative management of patients having periapical surgery, using the protocol of this study reduced postoperative pain.

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Effect of low-level laser therapy (LLLT) on peripheral nerve regeneration using fibrin glue derived from snake venom

Cited by 66 publications

References 41 publications

O uso terapêutico do LASER de Baixa Intensidade (LBI) em algumas patologias e sua relação com a atuação na Fonoaudiologia

O uso terapêutico do LASER de Baixa Intensidade (LBI) em algumas patologias e sua relação com a atuação na Fonoaudiologia

Low-Level Laser Therapy (LLLT) Improves the Repair Process of Peripheral Nerve Injuries: A Mini Review

Clinical efficacy of low level laser therapy in reducing pain and swelling after periapical surgery. A preliminary report.

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