Effect of green tea on postprandial antioxidant capacity, serum lipids, C-reactive protein and glucose levels in patients with coronary artery disease

Koutelidakis, Antonios E.; Rallidis, Lοukianos S.; Koniari, Katerina; Panagiotakos, Demosthenes B.; Komaitis, Michael; Zampelas, Antonis; Anastasiou-Nana, Maria; Kapsokefalou, Maria

doi:10.1007/s00394-013-0548-0

Cited by 39 publications

(42 citation statements)

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“…This may explain why plant-based dietary patterns have been demonstrated to protect against MetS and its individual components [6, 7]. Together with a decreased caloric intake, high consumption of antioxidant compounds has been hypothesized to play an important role in preventing this pathological condition [8–10]. …”

Section: Introductionmentioning

confidence: 99%

Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study

et al. 2016

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PurposeThe aim of this study was to evaluate the association between total and individual classes and subclasses of dietary polyphenol intake and prevalence of metabolic syndrome (MetS) in the Polish arm of the Health, Alcohol and Psychosocial factors In Eastern Europe cohort study.MethodsA cross-sectional population-based survey including 8821 adults (51.4 % female) was conducted in Kraków, Poland. Dietary polyphenol intake was evaluated using food frequency questionnaires and matching food consumption data with the Phenol-Explorer database. MetS was defined according to the International Diabetes Federation definition. Linear and logistic regression models were performed to estimate odds ratios (ORs) and confidence intervals (CIs).ResultsSignificant differences in age and energy intake among different categories of total dietary polyphenol intake were found. Body mass index (BMI), waist circumference (WC), blood pressure, and triglycerides were significantly lower among individuals in the higher quartiles of polyphenol intake, but a linear association was found only for BMI and WC. After adjusting for potential confounding factors, individuals in the highest quartile of polyphenol intake were less likely to have MetS (OR 0.80; 95 % CI 0.64, 0.98 and OR 0.70; 95 % CI 0.56, 0.86 for both men and women, respectively). High total polyphenol intake was negatively associated with WC, blood pressure, high lipoprotein cholesterol, and triglycerides in women, and fasting plasma glucose in both genders. Among individual classes of polyphenols, phenolic acids and stilbenes were significantly associated with MetS; lignans and stilbenes with WC; phenolic acids with blood pressure and triglycerides; and flavonoids with fasting plasma glucose. Among specific subclasses of polyphenols, hydroxycinnamic acids, flavanols, and dihydrochalcones had the most relevant role.ConclusionsTotal and individual classes and subclasses of dietary polyphenols were inversely associated with MetS and some of its components.Electronic supplementary materialThe online version of this article (doi:10.1007/s00394-016-1187-z) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study

et al. 2016

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“…A plausible mode of interaction occurs in the lumen where phenols alter the physicochemical characteristics of cholic acid micelles and the activity of the pancreatic and gastric lipases thereby inhibiting absorption of both lipids and phenols. 12,18,28 Alternatively, the absorbed phenols may not increase the TAC due to the rise of lipid hyperoxides from the fatty diet.…”

Section: Discussionmentioning

confidence: 97%

“…Although in this study phenols were not measured in organs, it may be speculated that the observed increased TAC was the result of the increased total phenolic content of GTE-supplemented diets. 6,8,16,27,28 Tea phenols, immediately after absorption across the small intestine and colon, enter in blood circulation as conjugates and move to organs. 8,13,14,16,29,30 The second important finding reported herein is that iron affected the bioactivity of GTE, resulting in lower TAC in liver and heart from mice receiving GTE + iron.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Iron and Fat in a Diet Containing Green Tea Extract (Camellia sinensis) on the Antioxidant Capacity of Some Organs and the mRNA Expression of Specific Genes in Mice

Koutelidakis

Kizis²,

Argyri³

et al. 2014

Journal of Medicinal Food

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The hypothesis that iron and fat in the diet may affect green tea extract (GTE) bioactivity, in particular antioxidant capacity and gene expression, was proposed and tested in mice. Thirty mice were randomly assigned to have for 37 days free access to standard or high-fat diets with or without GTE and ferrous lactate. Mice were euthanized and specific organs were removed. Total antioxidant capacity (TAC) was measured using the ferric reducing antioxidant power (FRAP) and oxygen radical absorbance capacity assays. Polymerase chain reaction was performed on liver and heart mRNA extracts. The FRAP assay showed that GTE from the standard diet did not affect plasma TAC but increased TAC of heart, aorta, and duodenum. GTE from diets enriched with iron resulted to lower TAC of liver and heart than diets with GTE alone. GTE from the fatty diet did not have any effect on TAC compared with fatty control diet, but increased TAC in heart and aorta compared with standard control diet. An effect on expression of the mapk-1 and NF-kB genes in heart was observed in the presence of GTE. These results suggest that GTE may exhibit bioactivity in some organs affected by dietary fat and iron. The findings of this study contribute to the elucidation of the role of dietary components on tea bioactivity.

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“…Several studies have shown the beneficial effects of green tea, including anti-hyperglycemic, anti-oxidative, anti-carcinogenic, anti-inflammatory and hypocholesterolemic activity [21,22,23]. For example, catechin-rich green tea improves postprandial glucose concentration and plasma antioxidant capacity in human subjects [24,25]. In a clinical trial, consumption of 1.5 g green tea extracts in 500 mL water (total polyphenols with approximately 500 mg gallic acid equivalent) with 75 g glucose decreased postprandial plasma glucose concentration in healthy subjects [26].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Isomaltulose Together with Green Tea on Glycemic Response and Antioxidant Capacity: A Single-Blind, Crossover Study in Healthy Subjects

et al. 2017

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Isomaltulose, a naturally-occurring isomer of sucrose, is commonly used as an alternative sweetener in foods and beverages. The goal of this study was to determine the effect of isomaltulose together with green tea on postprandial plasma glucose and insulin concentration, as well as antioxidant capacity in healthy subjects. In a randomized, single-blind, crossover study, 15 healthy subjects (eight women and seven men; ages 23.5 ± 0.7 years; with body mass index of 22.6 ± 0.4 kg/m2) consumed five beverages: (1) 50 g sucrose in 400 mL water; (2) 50 g isomaltulose in 400 mL of water; (3) 400 mL of green tea; (4) 50 g sucrose in 400 mL of green tea; and (5) 50 g isomaltulose in 400 mL of green tea. Incremental area under postprandial plasma glucose, insulin, ferric reducing ability of plasma (FRAP) and malondialdehyde (MDA) concentration were determined during 120 min of administration. Following the consumption of isomaltulose, the incremental 2-h area under the curve (AUC0–2 h) indicated a higher reduction of postprandial glucose (43.4%) and insulin concentration (42.0%) than the consumption of sucrose. The addition of green tea to isomaltulose produced a greater suppression of postprandial plasma glucose (20.9%) and insulin concentration (37.7%). In accordance with antioxidant capacity, consumption of sucrose (40.0%) and isomaltulose (28.7%) caused the reduction of green tea-induced postprandial increases in FRAP. A reduction in postprandial MDA after drinking green tea was attenuated when consumed with sucrose (34.7%) and isomaltulose (17.2%). In conclusion, green tea could enhance the reduction of postprandial glucose and insulin concentration when consumed with isomaltulose. In comparison with sucrose, isomaltulose demonstrated less alteration of plasma antioxidant capacity after being consumed with green tea.

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Effect of green tea on postprandial antioxidant capacity, serum lipids, C-reactive protein and glucose levels in patients with coronary artery disease

Abstract: Tea consumption did not affect selected biomarkers at any postprandial time point in patients with CAD.

Cited by 39 publications

References 32 publications

Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study

Dietary polyphenols are inversely associated with metabolic syndrome in Polish adults of the HAPIEE study

The Effect of Iron and Fat in a Diet Containing Green Tea Extract (Camellia sinensis) on the Antioxidant Capacity of Some Organs and the mRNA Expression of Specific Genes in Mice

The Effect of Isomaltulose Together with Green Tea on Glycemic Response and Antioxidant Capacity: A Single-Blind, Crossover Study in Healthy Subjects

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