Effect of Flavonoid-Rich Extract ofGlycyrrhiza glabraon Gut-Friendly Microorganisms, Commercial Probiotic Preparations, and Digestive Enzymes

Abstract

Flavonoid-rich extract prepared from Glycyrrhiza glabra has been found to be beneficial in patients with functional dyspepsia and was reported to possess some gut health-promoting properties such as antioxidant, anti-inflammatory and anti-Helicobacter pylori activities. In the present study, the flavonoid-rich extract of Glycyrrhiza glabra was evaluated for its compatibility with probiotic strains (Lactobacillus casei, Lactobacillus fermentum, Lactobacillus plantarum, and Streptococcus thermophilus), commercial probiotic drinks, and digestive enzymes (pancreatic α-amylase, α-glucosidase, phytase, xylanase, and pancreatic lipase). Results of this study indicated that the flavonoid-rich extract of Glycyrrhiza glabra is compatible with the tested probiotic strains, probiotic drinks and digestive enzymes.

Intestinal Microbiota Modulation in Obesity-Related Non-alcoholic Fatty Liver Disease

“…As mentioned before, Helicobacter pylori has been related to NAFLD. There are studies reporting a decline in Helicobacter genus or H. pylori using flavonoids (Feng et al, 2017; Porras et al, 2017), flavonoid rich extracts (Chua et al, 2016; Asha et al, 2017), and another natural compounds (Zulueta et al, 2015).…”

Evaluation of possible antioxidant activities of barberry solid formulation, a selected formulation from Traditional Persian Medicine (TPM) via various procedures

“…It has extensive root system and its soft, fibrous main taproot with the bright yellow interior is used for therapeutic purpose [18]. G. glabra root has antibacterial, anti-inflammatory, antiviral [19], anti-Helicobacter pylori [20], hypocholesterolemic, protective role against oxidative stress [21] and hypoglycemic effects [22]. It is used to treat liver diseases and is a major component of polyherbal formulations for the cure of hepatotoxicity in traditional medicine [23].…”