Effect of Coffee Drink Containing Mannooligosaccharides on Total Amount of Excreted Fat in Healthy Adults

Kumao, Toshio; Fujii, Shigeyoshi; Asakawa, Atsushi; Tanaka, Isao; Fukuhara, Ikuo

doi:10.1248/jhs.52.482

Cited by 22 publications

(18 citation statements)

References 4 publications

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“…It is well known that catechin, [13][14][15] mannooligosaccharides, 16,17) and coffee polyphenols 18) reduce body fat; however, it is unclear whether these ingredients improve liver function. The incidence of nonalcoholic steatohepatitis (NASH) is known to be strongly associated with obesity.…”

Section: Discussionmentioning

confidence: 99%

Preliminary Research for the Anti-obesity Effect of Puerariae Flos Extract in Humans

Kamiya

Matsuzuka

Kusaba

et al. 2011

JOURNAL OF HEALTH SCIENCE

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This research is preliminary study to examine whether puerariae flos extract (PFE) makes any action to body fat of man or not. We conducted the double-blind placebo controlled study on eighty mildly obese subjects for 8 weeks. The subjects were randomly divided into 4 groups: I, II, III, and IV. Subjects in groups I, II, and III consumed test food containing 100, 200, and 300 mg PFE, respectively, while those in group IV were given placebo food for 8 weeks. All subjects were instructed to restrict their total-energy intake to within 2650 kcal/day in the case of males and 2300 kcal/day in the case of females during the test period. Haematological and biochemical markers of blood, urinary markers, and physical markers were examined at 0, 4, and 8 weeks during the test period. As a result, no adverse effects were noted in any of the groups. For physical examinations, we analysed only males whose initial body mass index (BMI) values were over 24. BMI value and body weights of the subjects in group III were significantly reduced, and total fat area and subcutaneous fat area of the subjects in groups II and III were significantly reduced over the 8-week test period. Moreover, as a result of comparison among groups by unpaired t-test, significant difference appeared between group III and group IV in BMI. Total fat area in group III tend to decrease compared with group IV. By these results, the reduction of BMI in group III may reflect fat area reduction. To confirm the anti-obesity effect of PFE, we need to research particularly by extensive studies hereafter.

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Section: Discussionmentioning

confidence: 99%

Preliminary Research for the Anti-obesity Effect of Puerariae Flos Extract in Humans

Kamiya

Matsuzuka

Kusaba

et al. 2011

JOURNAL OF HEALTH SCIENCE

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“…Polyphenols have been reported to suppress postprandial elevation of triacylglycerol by promoting lipid excretion into feces, 15,16) so we considered that RMD would also have a similar function; promotion of lipid excretion. We conducted the animal and human experiments to confirm the effect of RMD on the lipid excretion into feces.…”

Section: Discussionmentioning

confidence: 99%

“…15) Fecal lipid excretion is considered to correspond with the lipid amount not absorpted in the small intestine, because lipid is not hydrolyzed or utilized by intestinal bacteria, unlike protein or carbohydrates. 19) Since the lipid excretion was significantly increased by the ingestion of RMD, it has been verified that RMD was associated with the reduction of lipid absorption.…”

Section: Discussionmentioning

confidence: 99%

Effect of Resistant Maltodextrin on Digestion and Absorption of Lipids

Kishimoto

Yoshikawa

Miyazato

et al. 2009

JOURNAL OF HEALTH SCIENCE

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In order to confirm the mechanism how postprandial elevation of triacylglycerol is suppressed by resistant maltodextrin (Fibersol-2), we conducted the following experiments. Firstly, Rats were fed a high-fat diet with resistant maltodextrin at 0% (control), 2.5% or 5% for 5 weeks to determine the lipid amount excreted in the feces of the last three days. The total lipid and triacylglycerol excreted in rat feces were significantly increased in a dose-dependent manner by the ingestion of resistant maltodextrin. Secondly, 10 healthy adult subjects were administrated a beverage containing 5 g resistant maltodextrin or placebo for 10 days, and crossed over after an 11-day washout. Total lipid excreted in feces was determined by collecting all the feces for the last three days. Fecal weight and fecal lipid amount of the subjects increased significantly with the ingestion of resistant maltodextrin compared to the placebo ingestion. Thirdly, oil emulsion prepared with resistant maltodextrin was assessed for its hydrolysis rate by lipase. The hydrolysis rate of lipid by lipase was not affected by resistant maltodextrin. Lastly, micelle emulsion was prepared with or without resistant maltodextrin, and their stability was compared. Resistant maltodextrin inhibited the decomposition of micelles and stabilized micellar structure. From these results, it was suggested that resistant maltodextrin suppresses lipid absorption and promotes the excretion of lipid into feces by delaying the release of fatty acids from micelles in the lipid absorption process. No inhibitory effect on lipase activity was observed by resistant maltodextrin.

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“…When mannooligosaccharides, which are also approved as FOSHU, were taken for 3 g/day, an increase of approximately 0.7-0.8 g/day of fecal fat was observed 12,13 . Therefore, to obtain an effective level of fecal fat excretion, it is necessary to increase the dosage of BOO.…”

Section: Discussionmentioning

confidence: 99%

The Consumption of a Structured Triacylglycerol Containing Behenic and Oleic Acids Increases Fecal Fat Excretion in Humans

Kojima

Arishima

Shimizu³

et al. 2013

J. Oleo Sci.

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Effect of Coffee Drink Containing Mannooligosaccharides on Total Amount of Excreted Fat in Healthy Adults

Cited by 22 publications

References 4 publications

Preliminary Research for the Anti-obesity Effect of Puerariae Flos Extract in Humans

Preliminary Research for the Anti-obesity Effect of Puerariae Flos Extract in Humans

Effect of Resistant Maltodextrin on Digestion and Absorption of Lipids

The Consumption of a Structured Triacylglycerol Containing Behenic and Oleic Acids Increases Fecal Fat Excretion in Humans

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