Mice were fed either a high fat diet or a high fat diet containing 1% mannooligosaccharides (MOS) for twelve weeks. The effects of MOS on fat accumulation and excretion were examined. After twelve weeks, the percentage weight of the fat and hepatic triglyceride level were significantly lower in the MOS group than that of the control group (p < 0.05 and p < 0.01 respectively). Furthermore, the serum triglyceride level had a decreasing tendency in the MOS group (p = 0.058). On the other hand, the fecal triglyceride level as well as the amount of fat excreted significantly increased in the MOS group (p < 0.05). This study showed that the administration of MOS lessened the fat accumulation in the parametrial adipose tissue and the liver while at the same time increased the amount of fat being excreted. These results indicate that MOS may prevent the fat storage through inhibiting the intestinal absorption of dietary fat in a high fat diet.
Liquid coffee and milk based liquid coffee, both containing 1.0 g of mannooligosaccharides (MOS) from coffee mannan, were administered to two groups of six subjects each. The subjects consumed one or the other of the beverage everyday for two weeks. The level of fat in their excrement was subsequently analyzed. In both liquid coffee (p < 0.05, respectively) and milk based liquid coffee (p < 0.05, respectively), the concentration of the beverage containing MOS intake showed a significant decrease in comparison with the placebo and interval or those who did not drink any coffee. The result suggests that the intake of MOS can increase the level of fat excreted from the body irrespective.
A liquid coffee drink containing mannooligosaccharides from coffee mannan (MOS) was administered to a group of healthy adults. Subsequently, the amount of fat excreted from the body was examined. The subjects were divided into two groups: One was administered a liquid coffee drink containing MOS 3.0 g/day whereas the other was administered a placebo drink for seven days. Both groups were fed the standardized meals during the experiment. In the amount of average excreted fat, the drink containing MOS intake showed a significant increase in comparison with the before intake group and placebo intake group (p < 0.05 and p < 0.001, respectively). In addition, fat utilization in MOS intake group was significantly lower than the before intake group and the placebo group (p < 0.05 and p < 0.001, respectively). These results suggested that the intake of MOS 3.0 g/day increased in the amount of excreted fat and decreased in fat utilization.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.