Efek Minuman Keras Oplosan terhadap Perubahan Histopatologi Organ Renal Tikus Wistar Jantan

Abstract


 Mixed liquor is a liquor mixed with other substances, mainly ethanol and methanol. Mixed liquor can cause kidney destruction. The aim of this study was to investigate the effect of mixed liquor toward kidney's microscopic and macroscopically changes. This study used 24 rats which were divided into 4 groups consist of 1 control group and 3 experimental groups. The first, second, and third experimental groups were given ethanol 1,296ml/2 days; methanol 0,2592ml/2days and aquades 1,4448ml/2 days for 5 days; 11 days and 17 days, respectively. Afterward rats were terminated and the right kidney mass was measured. The kidney tissue was prepared for histological examination and the number of necrotic cell was calculated. According to Kruskal Wallis test, kidney mass was not significantly different (p>α) while total necrotic cells was significantly different (p<α). This study showed that rats induced with mixed liquor for 5 , 11, and 17 days resulted in kidney microscopically change.

The Knowledge of Non-Medical Individuals in Surabaya Regarding Basic Life Support

“…52.9% of the university student respondents of this research know which is the correct location for chest compression. This is quite low when compared to a research that was conducted among university students in Malaysia which shows 70.5% of the respondents were able to give a correct answer regarding the location for chest compression [14]. But, when compared to a study done in Saudi Arabia, the score of this study's university student respondents is higher.…”

“…For the proper chest compression rate and chest compression depth, 30.3% and 47.1% of this research's respondents know the correct answer. Although the number is quite low, it is still better when compared to the research among university students in Saudi Arabia that shows 24.2% of the respondents know the proper chest compression rate and 40.8% of the respondents know the proper chest compression depth [14]. Although not all questions were eliminated, this data indicates that the comprehension of the workers in this research regarding those eliminated questions are still lower than the university students.…”

“…But, when compared to a study done in Saudi Arabia, the score of this study's university student respondents is higher. From the research among university students in Saudi Arabia, it shows that 44% of the respondents know the correct location for chest compression [14]. For the proper chest compression rate and chest compression depth, 30.3% and 47.1% of this research's respondents know the correct answer.…”

Formulation and Analysis of Alcohol Content in Pineapple Infused Arak Bali with Gas Chromatography

“…The polar nature of ethanol makes this chemical often used as a drug solvent, preservative in the medical world, disinfectant and is usually used as an antidote (compound that reduces or eliminates toxicity) methanol and ethylene glycol poisoning. The content of ethanol in liquor in small quantities provides the advantage of a warm taste (Ayuningtyas, 2016;Sukadana & Tenaya, 2016).…”

Potensi Ekstrak Teripang (Holothuria leucospilota) Sebagai Anti Tukak Lambung pada Mencit (Mus musculus) yang Diinduksi Minuman Keras (Miras) Oplosan

“…Berbagai macam faktor dapat memicu timbulnya penyakit tukak lambung, salah satunya adalah sering mengkonsumsi minuman keras atau minuman beralkohol (Kementrian Kesehatan RI, 2014). Kawiartha (2016) mengatakan bahwa, di Indonesia minuman alkohol yang sering dikonsumsi adalah minuman alkohol yang telah dicampur dengan bahan lain atau yang biasa disebut dengan minuman keras (miras) oplosan. Jenis alkohol yang sering ditemukan dalam miras oplosan di masyarakat adalah metanol (Respatiadi dan Tandra, 2018).…”