Eco-friendly synthesis of gold nanoparticles using fruit extracts and in vitro anticancer studies

Vijayakumar, S.

doi:10.1016/j.jscs.2018.12.002

Cited by 50 publications

(19 citation statements)

References 36 publications

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“…The high chemical stability, optical properties, oxidation resistance and biocompatibility properties of gold nanoparticles and their applications in different field of study such as biology, optics and medicine make synthesis of gold nanoparticles an interesting object of study [10]. The advantage of synthesizing gold nanoparticles from plant extract is not limited to reduction of environmental toxicity, the production of nanoparticles in large quantities, simplicity of reducing metal salts, rapid, cost effective, and safety for clinical research to nanoparticles are other advantages associated with this method of synthesis, the green synthesized gold nanoparticle can be used in development of catalysts, sensors, nano medicine and biomarker applications [11]. Gold nanoparticles exhibit properties that are different from that of bulk gold and can be manufactured into various shapes such as nanorods, nanostars, nanobelts, nanospheres, nanocages and nanoprisms [12].…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata

et al. 2019

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The need to divulge the rapid synthesis, non-hazardous, cost effectiveness and eco-friendly methods for the synthesis of nanoparticles utilizing plants is of great importance. This is as a result of high toxicity associated with the chemical method of synthesizing nanoparticles. The aim of this study was to investigate the potency of the synthesized gold nanoparticle against selected human pathogens. Gold nanoparticles were synthesized by reacting 1 mM gold chloride solution with leaf extract of Annona muricata. The synthesized gold nanoparticles were characterized with UV-visible spectrophotometer, transmission electron microscope (TEM) and Fourier transformed infrared spectroscopy (FTIR). The antibacterial and antifungal activities of the synthesized gold nanoparticles were also investigated. The morphology, size, and structural properties of synthesized gold nanoparticles were determined with TEM analysis which showed spherical mono-dispersed structure with an average particle size of 25.5 nm. FTIR analysis reveal band at 3271.14, 2111.91 and 1637.82 cm −1 corresponding toN -H,-C=C, and-C-N functional groups that are responsible for the capping and stabilization of synthesized gold nanoparticles. The effectiveness of the gold nanoparticle against the test pathogens increases as the concentration of gold nanoparticle increases. The percentage of zones of inhibition of synthesized gold nanoparticle against test fungi and bacteria ranges from 30 to 66% and 40 to 54%, respectively. The potency of the synthesized gold nanoparticle against the selected fungi and bacteria increases with increase in concentration of gold nanoparticle. Therefore, the antibacterial and antifungal investigation revealed that the synthesized gold nanoparticles exhibited good antimicrobial activity.

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Section: Introductionmentioning

confidence: 99%

Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata

et al. 2019

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“…The cytotoxic investigation of AuNPs against the growth of human breast cancer cells (MCF-7) showed 60% cell death at concentrations of 120 mg/ml. It was also observed that the cytotoxicity increased with the increase in concentration of AuNPs [ 83 ]. Findings had shown that the anticancer efficiency of AuNPs depends on the stabilizing agent and size [ 106 ].…”

Section: Applications Of Aunps Synthesized From Plant Extractsmentioning

confidence: 99%

Bioremediation and pharmacological applications of gold nanoparticles synthesized from plant materials

Akintelu

Yao

Folorunso

2021

Heliyon

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Nanotechnology and nanoscience are gaining remarkable attention in this era due to their distinctive properties and multi applications. Gold nanoparticles (AuNPs) is one of the most relevant metal nanoparticles with enormous applications in various field of research and industries. The demand for AuNPs is increasing rapidly. Extensive awareness has been allotted to the development of novel approaches for the synthesis of AuNPs with quality morphological properties using biological sources due to the limitations associated with the chemical and physical methods. Several factors such as contact time, temperature, pH of solution media, concentration of gold precursors and volume of plant extract influences the synthesis, characterization and applications of AuNPs. Characterization of synthesized AuNPs is important in evaluating the morphological properties of AuNPs since the morphological properties of AuNPs affect their potential use in various applications. This review highlights various methods of synthesizing AuNPs, parameters influencing the biosynthesis of AuNPs from plant extract, several techniques used for AuNPs characterization and their potential in bioremediation and biomedical applications.

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“…The nanoparticles were developed upon reaction between tetra chloroauric acid and extracts of fruits extracts with aurum chloride. The colour of the mixture was turned red to pale yellow, which indicated the formation of gold nanoparticles 19 . The formulations were characterized by Fourier transformed infrared spectroscopy, zeta potential analysis, transmission electron microscopy, and they were evaluated biologically against (MCF-7) breast cancer cell line.…”

Section: Antifungal Activites: Candida Albicans Puccinia Graminis Pleurotus Conrnucopie Var Citrniopileatus Cladosporium Cladosporiodesmentioning

confidence: 99%

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2021

IJPSR

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Eco-friendly synthesis of gold nanoparticles using fruit extracts and in vitro anticancer studies

Cited by 50 publications

References 36 publications

Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata

Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata

Bioremediation and pharmacological applications of gold nanoparticles synthesized from plant materials

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