2021
DOI: 10.1016/j.ijrobp.2020.12.018
|View full text |Cite
|
Sign up to set email alerts
|

Early MRI Blood Volume Changes in Constrictor Muscles Correlate With Postradiation Dysphagia

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

2022
2022
2024
2024

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 7 publications
(3 citation statements)
references
References 26 publications
0
3
0
Order By: Relevance
“…Recently, advanced functional MRI imaging has been applied to measure tissue changes during the course of radiotherapy treatment, with the intent to understand an individuals’ risk of tissue toxicity, and improve the therapeutic ratio of radiation. Mierzwa et al [13 ▪ ] reported novel findings from applying dynamic contrast-enhanced (DCE) MRI to measure blood volumes changes at baseline and mid-radiotherapy treatment, and explore its association with swallowing-related endpoints posttreatment in patients with oropharyngeal cancer. That study revealed a significant increase in blood volumes to the pharyngeal constrictor muscles, suggestive of early inflammation and oedema, and associations between increased PCM blood volume and feeding-tube dependence and aspiration posttreatment.…”
Section: Imaging In Dysphagiamentioning
confidence: 99%
“…Recently, advanced functional MRI imaging has been applied to measure tissue changes during the course of radiotherapy treatment, with the intent to understand an individuals’ risk of tissue toxicity, and improve the therapeutic ratio of radiation. Mierzwa et al [13 ▪ ] reported novel findings from applying dynamic contrast-enhanced (DCE) MRI to measure blood volumes changes at baseline and mid-radiotherapy treatment, and explore its association with swallowing-related endpoints posttreatment in patients with oropharyngeal cancer. That study revealed a significant increase in blood volumes to the pharyngeal constrictor muscles, suggestive of early inflammation and oedema, and associations between increased PCM blood volume and feeding-tube dependence and aspiration posttreatment.…”
Section: Imaging In Dysphagiamentioning
confidence: 99%
“…Initial efforts toward consensus guidelines for qMRI on MRgRT systems have recently begun. 22 However, the current focus of qMRI in RT is on the target volume, where QIBs that monitor normal tissue toxicity 121 could be further explored. To further develop guidelines for RT QIBs, there are opportunities to learn from and work with the diagnostic qMRI community, building on pre‐existing work.…”
Section: Quantitative Mrimentioning
confidence: 99%
“…Early work in MRI has shown that diffusion-weighted imaging may be predictive of outcomes [ 36 , 37 ]. Blood volume changes seen on MRI early in the course of RT may predict oncologic outcomes [ 38 ] or even functional outcomes such as dysphagia [ 39 ]. Additional integration of clinical information such as tumor-infiltrating lymphocytes [ 40 ], genomics, or mutational status [ 41 ] may offer predictors that can be incorporated with radiomics data.…”
Section: Developing Areasmentioning
confidence: 99%