Early morphological changes in tissues when replacing abdominal wall defects by bacterial nanocellulose in experimental trials

Zharikov, A.N.; Lubyansky, Vladimir G.; Гладышева, Е. К.; Скиба, Е. А.; Будаева, В. В.; Semyonova, Elena N.; Zharikov, Andrey A.; Сакович, Г. В.

doi:10.1007/s10856-018-6111-z

Cited by 20 publications

(23 citation statements)

References 29 publications

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“…However, the type of prosthesis best suitable for this purpose is not well established. There is a variety of materials for hernia repair; polypropylene (PP) (Zharikov et al 2018) and polytetrafluorethylene (PTFE) (Silveira et al 2016) are the most commonly used today. Although they have positive properties, drawbacks like chronic pain produced by fibrous tissue; inflammation of the surrounding tissues; reduced abdominal wall mobility; foreign body sensation at the implant site and infections are often noticed (Zharikov et al 2018).…”

Section: Soft Tissue Engineeringmentioning

confidence: 99%

“…There is a variety of materials for hernia repair; polypropylene (PP) (Zharikov et al 2018) and polytetrafluorethylene (PTFE) (Silveira et al 2016) are the most commonly used today. Although they have positive properties, drawbacks like chronic pain produced by fibrous tissue; inflammation of the surrounding tissues; reduced abdominal wall mobility; foreign body sensation at the implant site and infections are often noticed (Zharikov et al 2018). The ideal mesh for abdomen reconstruction should be strong and resistant to infections, biocompatible, non-immunogenic, with minimal bio-reactivity, easily incorporated by surrounding tissues and non-adhesive.…”

Section: Soft Tissue Engineeringmentioning

confidence: 99%

“…However, no current mesh meets all these requirements (Silveira et al 2016). In this regard, it is mandatory to find and use new materials in herniology (Zharikov et al 2018).…”

Section: Soft Tissue Engineeringmentioning

confidence: 99%

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Applications of bacterial-synthesized cellulose in veterinary medicine – a review

et al. 2019

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Tissue engineering promotes tissue regeneration through biomaterials that have excellent properties and have the potential to replace tissues. Many studies show that bacterial cellulose (BC) might ensure tissue regeneration and substitution, being used for the bioengineering of hard, cartilaginous and soft tissues. Bacterial cellulose is extensively used as wound dressing material and results show that BC is a promising tissue scaffold (bone, cardiovascular, urinary tissue). It can be combined with polymeric and non-polymeric compounds to acquire antimicrobial, cell-adhesion and proliferation properties. To ensure proper tissue regeneration, the material has to be: biocompatible, with minimum tissue reaction and biodegradability; bio-absorbable, to promote tissue development, cellular interaction and grow; resistant to support the weight of the newly formed tissue. Its versatile structure, physical and biochemical properties can be adjusted by adapting the bacteria culturing conditions. The main biomedical applications seem to be as hard (bone, dental), fibrocartilaginous (meniscal) and soft tissue (skin, cardiovascular, urinary) substituents. This paper reviews the current state of knowledge, challenges and future applications of BC and its biomedical potential in veterinary medicine. It was focused on the main uses in regeneration and scaffold tissue replacement and, although BC showed promising results, there is a lack of successful results of BC use in clinical practice. Most studies were performed only at experimental level and further research is needed for BC to enter clinical veterinary practice.

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Section: Soft Tissue Engineeringmentioning

confidence: 99%

Section: Soft Tissue Engineeringmentioning

confidence: 99%

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Applications of bacterial-synthesized cellulose in veterinary medicine – a review

et al. 2019

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“…Other important species include Gluconacetobacter hansenii [3,50,51], Gluconacetobacter kombuchae [52], Komagataeibacter (Gluconacetobacter) europaeus [53], and low pH-resistant strain Komagataeibacter (Gluconacetobacter) medellinensis [42]. The bacterial growth and production of nanocellulose can be further enhanced by the presence of yeasts or yeast extract in the culture medium [52,54], or by symbiotic co-cultivation with Мedusomyces gisevii [55].…”

Section: Introductionmentioning

confidence: 99%

Versatile Application of Nanocellulose: From Industry to Skin Tissue Engineering and Wound Healing

et al. 2019

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Nanocellulose is cellulose in the form of nanostructures, i.e., features not exceeding 100 nm at least in one dimension. These nanostructures include nanofibrils, found in bacterial cellulose; nanofibers, present particularly in electrospun matrices; and nanowhiskers, nanocrystals, nanorods, and nanoballs. These structures can be further assembled into bigger two-dimensional (2D) and three-dimensional (3D) nano-, micro-, and macro-structures, such as nanoplatelets, membranes, films, microparticles, and porous macroscopic matrices. There are four main sources of nanocellulose: bacteria (Gluconacetobacter), plants (trees, shrubs, herbs), algae (Cladophora), and animals (Tunicata). Nanocellulose has emerged for a wide range of industrial, technology, and biomedical applications, namely for adsorption, ultrafiltration, packaging, conservation of historical artifacts, thermal insulation and fire retardation, energy extraction and storage, acoustics, sensorics, controlled drug delivery, and particularly for tissue engineering. Nanocellulose is promising for use in scaffolds for engineering of blood vessels, neural tissue, bone, cartilage, liver, adipose tissue, urethra and dura mater, for repairing connective tissue and congenital heart defects, and for constructing contact lenses and protective barriers. This review is focused on applications of nanocellulose in skin tissue engineering and wound healing as a scaffold for cell growth, for delivering cells into wounds, and as a material for advanced wound dressings coupled with drug delivery, transparency and sensorics. Potential cytotoxicity and immunogenicity of nanocellulose are also discussed.

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“…Creating protective barriers involves designing materials that prevent intraperitoneal adhesions or immune rejection of transplanted cells. For example, in experimental abdominal defects in dogs, which were repaired using BNC membranes, negligible intraperitoneal adhesions were detected between the BNC and the intestinal loops in comparison with conventionally-used polypropylene meshes [47]. Modifying polypropylene meshes, and also metallic meshes, with BNC enhanced their potential applicability in hernioplasty and cranioplasty [189].…”

Section: Recent Use Of Nanocellulose In Tissue Engineering and Tissuementioning

confidence: 99%

Nanocellulose in Biotechnology and Medicine: Focus on Skin Tissue Engineering and Wound Healing

Bacakova¹,

Pajorová²,

Bačáková³

et al. 2018

Preprint

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Nanocellulose is cellulose in the form of nanostructures, i.e. features not exceeding 100 nm at least in one dimension. These nanostructures include nanofibrils, e.g. in bacterial cellulose; nanofibers, e.g. in electrospun matrices; nanowhiskers and nanocrystals. These structures can be further assembled into bigger 2D and 3D nano-, micro- and macro-structures, such as nanoplatelets, membranes, films, microparticles and porous macroscopic matrices. There are four main sources of nanocellulose: bacteria (Gluonacetobacter), plants (trees, shrubs, herbs), algae (Cladophora) and animals (Tunicata). Nanocellulose has emerged for a wide range of industrial, technology and biomedical applications, e.g. for adsorption, ultrafiltration, packaging, conservation of historical artifacts, thermal insulation and fire retardation, energy extraction and storage, acoustics, sensorics, controlled drug delivery, and particularly for tissue engineering. Nanocellulose is promising for use in scaffolds for engineering of blood vessels, neural tissue, bone, cartilage, liver, adipose tissue, urethra and dura mater, for repairing connective tissue and congenital heart defects, and for constructing contact lenses and protective barriers. This review is focused on applications of nanocellulose in skin tissue engineering and wound healing as a scaffold for cell growth, for delivering cells into wounds, and as a material for advanced wound dressings coupled with drug delivery, transparency and sensorics. Potential cytotoxicity and immunogenicity of nanocellulose are also discussed.

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Early morphological changes in tissues when replacing abdominal wall defects by bacterial nanocellulose in experimental trials

Cited by 20 publications

References 29 publications

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

Versatile Application of Nanocellulose: From Industry to Skin Tissue Engineering and Wound Healing

Nanocellulose in Biotechnology and Medicine: Focus on Skin Tissue Engineering and Wound Healing

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