Drinking water pollutants may affect the immune system: concerns regarding COVID-19 health effects

Quinete, Natalia; Hauser‐Davis, Rachel Ann

doi:10.1007/s11356-020-11487-4

Cited by 58 publications

(32 citation statements)

References 114 publications

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“…In turn, the link between environmental pollution and immunity is of particular interest as various pollutants may provoke immunotoxic effects. Among these pollutants, some toxic metals can cause immunotoxicity in humans ( Cohen, 2018 ; Hultman and Pollard KM, 2015; Quinete and Hauser-Davis, 2021 ). Environmental factors, such as air and drinking water contaminants, may contribute to the increased prevalence of allergies and autoimmune diseases, many of which are due to the activity of Th17 T cells ( Tsatsakis et al, 2020 ).…”

Section: Toxic Metals/metalloids and Covid-19mentioning

confidence: 99%

The effects of some essential and toxic metals/metalloids in COVID-19: A review

Domingo

Marquès

2021

Food and Chemical Toxicology

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Thousands of studies have been conducted in order to understand in depth the characteristics of the novel coronavirus SARS-CoV-2, its infectivity and ways of transmission, and very especially everything related to the clinical and severity of the COVID-19, as well as the potential treatments. In this sense, the role that essential and toxic metals/metalloids have in the development and course of this disease is being studied. Metals/metalloids such as arsenic, cadmium, lead, mercury or vanadium, are elements with known toxic effects in mammals, while trace elements such as cobalt, copper, iron, manganese, selenium and zinc are considered essential. Given the importance of metals/metalloids in nutrition and human health, the present review was aimed at assessing the relationship between various essential and toxic metals/metalloids and the health outcomes related with the COVID-19. We are in the position to conclude that particular attention must be paid to the load/levels of essential trace elements in COVID-19 patients, mainly zinc and selenium. On the other hand, the exposure to air pollutants in general, and toxic metal/metalloids in particular, should be avoided as much as possible to reduce the possibilities of viral infections, including SARS-CoV-2.

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Section: Toxic Metals/metalloids and Covid-19mentioning

confidence: 99%

The effects of some essential and toxic metals/metalloids in COVID-19: A review

Domingo

Marquès

2021

Food and Chemical Toxicology

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“…One of the main sources of human exposure to pollutants is through drinking water [ 140 ]. This directs the attention to some major contaminants in drinking water known to be immune-toxic and drinking water routes, which could possibly compromise the effective immune response of humans [ 146 , 147 ].…”

Section: Thematic Discussionmentioning

confidence: 99%

COVID-19 and environmental concerns: A rapid review

Sharma

Tiwari

Jain

et al. 2021

Renewable and Sustainable Energy Reviews

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COVID-19 has slowed global economic growth and consequently impacted the environment as well. Parallelly, the environment also influences the transmission of this novel coronavirus through various factors. Every nation deals with varied population density and size; air quality and pollutants; the nature of land and water, which significantly impact the transmission of coronavirus. The WHO (Ziaeepour et al., 2008) [1] has recommended rapid reviews to provide timely evidence to the policymakers to respond to the emergency. The present study follows a rapid review along with a brief bibliometric analysis of 328 research papers, which synthesizes the evidence regarding the environmental concerns of COVID-19. The novel contribution of this rapid review is threefold. One, we take stock of the diverse findings as regards the transmission of the novel coronavirus in different types of environments for providing conclusive directions to the ongoing debate regarding the transmission of the virus. Two, our findings provide topical insights as well as methodological guidance for future researchers in the field. Three, we inform the policymakers on the efficacy of environmental measures for controlling the spread of COVID-19.

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“…Figure 1 summarizes immunogenetic factors discussed in the present review [ 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 , 212 , 213 ].…”

Section: Other Immune Response Genesmentioning

confidence: 99%

The Role of Immunogenetics in COVID-19

Pojero

Candore

Caruso

et al. 2021

IJMS

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Coronavirus disease 2019 (COVID-19) is induced by SARS-CoV-2 and may arise as a variety of clinical manifestations, ranging from an asymptomatic condition to a life-threatening disease associated with cytokine storm, multiorgan and respiratory failure. The molecular mechanism behind such variability is still under investigation. Several pieces of experimental evidence suggest that genetic variants influencing the onset, maintenance and resolution of the immune response may be fundamental in predicting the evolution of the disease. The identification of genetic variants behind immune system reactivity and function in COVID-19 may help in the elaboration of personalized therapeutic strategies. In the frenetic look for universally shared treatment plans, those genetic variants that are common to other diseases/models may also help in addressing future research in terms of drug repurposing. In this paper, we discuss the most recent updates about the role of immunogenetics in determining the susceptibility to and the history of SARS-CoV-2 infection. We propose a narrative review of available data, speculating about lessons that we have learnt from other viral infections and immunosenescence, and discussing what kind of aspects of research should be deepened in order to improve our knowledge of how host genetic variability impacts the outcome for COVID-19 patients.

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Drinking water pollutants may affect the immune system: concerns regarding COVID-19 health effects

Cited by 58 publications

References 114 publications

The effects of some essential and toxic metals/metalloids in COVID-19: A review

The effects of some essential and toxic metals/metalloids in COVID-19: A review

COVID-19 and environmental concerns: A rapid review

The Role of Immunogenetics in COVID-19

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