DNA interaction studies of a novel Cu(II) complex as an intercalator containing curcumin and bathophenanthroline ligands

Synthesis and Characterization of some Ternary Metal Complexes of Curcumin with 1,10-phenanthroline and their Anticancer Applications

“…The antibacterial activities tests showed that all these complexes had excellent antibacterial ability against E. coli and H. bacillus. Copper(II) mixed ligand complex of curcumin with diphenylphenanthroline, Cu(Cur)(DIP)] 2+ was synthesized and the binding mode of the complex with CT-DNA was investigated [23]. The aim of this work is synthesis, characterization and biological activities of the new Ni(II), Co(II), Cu(II) and Zn(II) ternary complexes with curcumin as primary ligand and 1,10-phenanthroline (phen) as supporting ligand.…”

Probing the interaction of troxerutin with transfer RNA by spectroscopic and molecular modeling

“…Additionally, interaction of TXER with tRNA shows decreased peak current. These observations may be due to interaction of TXER with tRNA by external or electrostatic binding fashion [28,40].…”

“…UV-visible absorption spectroscopy is one of the most versatile techniques for studying the binding mechanism of small molecule to macromolecules [28]. Absorption spectra of the tRNA alone and tRNA-TXER complex at various concentrations of TXER are presented in Fig.…”

Synthesis and characterization of efficient chemical nucleases: A joint refinement from XRD, antimicrobial screening, DNA binding and cleavage investigations

“…If one strand is cleaved, the supercoils will relax to produce a slowly moving open circular form (Form II). If both strands are cleaved, a linear form (Form III) will be generated that migrates in between [35,36]. All the complexes are found to exhibit nuclease activity.…”