Distribution of Human Papilloma Virus (HPV) in Cervical Adenocarcinoma and Adenosquamous Carcinoma

Cervical cancer is one of the most common cancers found in Indonesia however it has not yet been properly resolved. Anatomical pathology archive data of histopathological features from cervical dysplasia and cancer lesions of 108 patients, who met the inclusion criteria, at MRCCC Siloam Hospital Semanggi in 2018 to 2020 are collected. This study is using retrospective design. Techniques were used to get the specimens are 66.7% cervical biopsy and 33.3% hysterectomy. There were 21.3%, 40.7% and 38% patients who were diagnosed with cervical dysplasia or cancer respectively in 2018, 2019 and 2020. Most of them who were diagnosed with cervical dyplasia lesions at the age of 20-29 and those with cervical cancer were at the age of 40-49. HPV DNA examination results show 21.3% were positive for High-Risk HPV types and 1.9% had positive results for a combination of High-Risk and Low-Risk types, which HPV type 16 was found the most. Histopathological examination intepretations of patients with dyplasia shows 61.9% had LSIL and 38.1% had HSIL. Those with cervical cancer shows 65.2% had squamous cell carcinoma and 34.8% had adenocarcinoma. Risk factors have important role in cervical dysplasia that can develop into cervical cancer, especially HPV infection. Routine test and histopathological examination are the only way to find out the possibility of cervical dysplasia/precancerous lesion or cancer so patients could receive prompt and appropriate management sooner.

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“…31. 33. and 45 are the cause of invasive cervical cancer cases worldwide [49]. In a study conducted by Vet JNI et al in Indonesia.…”

Section: Resultsmentioning

confidence: 99%

The profile of cervical dysplasia and cervical cancer of patients at MRCCC siloam Hospital Semanggi

Panjaitan¹,

Susanto²,

Gultom³

et al. 2023

World J. Bio. Pharm. Health Sci.

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“…This study evaluated the distribution of HPV genotype in cervical adenocarcinoma and adenosquamous carcinoma. A cross-sectional study (Mastutik et al, 2021) was conducted at the Department of Anatomic Pathology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2015.…”

Section: Introductionmentioning

confidence: 99%

“…All of the specimens were infected by HPV. In cervical adenocarcinoma, the infection was by HPV 6,11,16,18,31,45, 68B, and 72, and in adenosquamous carcinoma by HPV 6,16,18,45,and…”

Section: Introductionmentioning

confidence: 99%

Relevancy Between Knowledge and Attitudes of Students to Human Papillomavirus (HPV) Vaccine: Literature Review

Octavilia¹,

Amalia²

2023

International Journal of Scientific Advances

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Background: University students are the key population to be prioritized in terms of uptake and coverage of the HPV vaccine. HPV program policies have recently shifted to target pre- and early pubertal adolescents before the age of 13 years. Evidence shows that adolescents aged 13 and over are less likely to complete the HPV vaccine series. Currently, 23 million young adults aged 19-26 years are not vaccinated. In 2016, only 16% of unvaccinated children aged 13 to 17 years received both doses. In addition, adolescents are less likely to start the HPV vaccine as they age, with only 7% initiation after age 15. Such lower vaccination rates raise the need for an effective follow-up vaccination strategy that targets young populations beyond the recommended adult vaccination schedule. In fact, the CDC’s Advisory Committee on Immunization practices recently recommended expanding the vaccination age range to 26 for both men and women, and for clinicians to engage in shared decision-making with older patients (ages 27-45) who might benefit of its use. Method: This article using method literature review. It is use selected journals or articles according to the author’s criteria and analyzing them to produce a conclusion. Authors using two international database is Pubmed and Sciencedirect with the keyword “knowledge and attitudes”, “students”, and “HPV vaccine”. The analysis of the articles used is based on the publication time span of the last 5 years (2018- 2022). The type of journal used is original, full text, and open access. The design of this article was taken using case control and cross-sectional methods. Result: The result of a literature search on database by Pubmed and Sciencedirect, there are 407 journals according to keywords and time spans. There are 122 journals from Pubmed and 285 journals from Sciencedirect. Authors filtered by the title, abstract, method, and result to find relevancy between knowledge and attitudes of students to HPV Vaccine. Total of 20 articles related to this article. Conclusion: On average, studies from various journals state that their findings have a lot to do with knowledge and attitudes towards the HPV vaccine, so it is advisable to further promote this knowledge so that there will be more students’ positive attitudes towards the HPV vaccine.

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Optimization of multiplex polymerase chain reaction (PCR) to detect human papillomavirus (HPV) type 6 and type 11 infection

Atikana,

Setiawan,

Husna

et al. 2024

The 7TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: The 15th Asian Congre

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Distribution of Human Papilloma Virus (HPV) in Cervical Adenocarcinoma and Adenosquamous Carcinoma

Cited by 5 publications

References 24 publications

The profile of cervical dysplasia and cervical cancer of patients at MRCCC siloam Hospital Semanggi

The profile of cervical dysplasia and cervical cancer of patients at MRCCC siloam Hospital Semanggi

Relevancy Between Knowledge and Attitudes of Students to Human Papillomavirus (HPV) Vaccine: Literature Review

Optimization of multiplex polymerase chain reaction (PCR) to detect human papillomavirus (HPV) type 6 and type 11 infection

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