Direct assay of uroporphyrin and coproporphyrin in human urine by reverse-mode field amplified sample injection-sweeping and micellar electrokinetic chromatography

Optical and electrochemical behavior of new nano-sized complexes based on gold-colloid and Co-porphyrin derivative in the presence of H 2 O 2

“…4) with increasing the amounts of Co(II)-porphyrin, meaning that gold colloid is suitable as optical sensor for small amounts of porphyrin detection. This result might find valuable medical applications due to the importance in detecting porphyrin derivatives and metabolites present in the human body in early diagnosis of different diseases [23].…”

Capillary Electrophoresis: Trends and Recent Advances

“…Electrophoretic sample preconcentration in CE often relies on an abrupt and temporary reduction of the migration velocity of analytes. This is clear in commonly applied methods like field-amplified sample stacking (FASS), large-volume sample stacking/injection (LVSS/LVSI), field-enhanced sample injection (FESI), , sweeping, and electrokinetic supercharging (EKS) . The fundamentals of electrokinetic processes occurring during FASS were studied experimentally and with computer simulation by Sestak and Thormann .…”

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2014–2016)

“…These combinations enable longer sample injections than by FASI or FASS alone because of the focusing of the overloaded sample injection by MSS or sweeping. There were six, one and four paper(s) on FASI–sweeping , FASS‐sweeping , and FASI‐MSS , respectively. In addition, two reports applied the combination of FASI‐sweeping‐MSS in a three‐step stacking approach .…”

“…In FASI‐sweeping, the cationic analytes were propranolol enantiomers , homocysteine thiolactone , β‐blockers , and the heavy metals Pb(II), Cu(II), Hg(II), Zn(II), and Co(II) . The anionic metabolites uroporphyrin and coproporphyrin were also studied . The samples included human saliva, blood, and urine, and environmental waters.…”