Differences in Rates and Short-term Outcome of Live Births Before 32 Weeks of Gestation in Europe in 2003: Results From the MOSAIC Cohort

Zeitlin, Jennifer; Draper, Elizabeth S; Kollée, L.A.A.; Milligan, David; Boerch, Klaus; Agostino, Rocco; Gortner, Ludwig; Reempts, Patrick J Van; Chabernaud, J.-L.; Gadzinowski, Janusz; Breart, Gérard; Papiernik, E

doi:10.1542/peds.2007-1620

Cited by 130 publications

(102 citation statements)

References 43 publications

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“…Regions represented different organizational models of perinatal care, based on the results of a previous European collaboration. The study's further objectives were to describe the organization of maternity and neonatal units [11] and to assess regional perinatal health outcome, using predefined variables [12] .…”

Section: Methodsmentioning

confidence: 99%

Rates of Bronchopulmonary Dysplasia in Very Preterm Neonates in Europe: Results from the MOSAIC Cohort

Gortner

Misselwitz²,

Milligan³

et al. 2010

Neonatology

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117

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Background: A considerable local variability in the rate of bronchopulmonary dysplasia (BPD) has been recorded previously. Objectives: The objectives of the present study were to describe regional differences in the rate of BPD in very preterm neonates from a European population-based cohort and to further delineate risk factors. Methods: 4,185 survivors to 36 weeks’ postmenstrual age of 4,984 live-born infants born at 24+0–31+6 weeks’ gestation in 2003 (the MOSAIC cohort) in 10 European regions were enrolled using predefined structured questionnaires. Results: Overall median gestational age of preterms without BPD was 30 weeks (range 23–31), median birth weight 1,320 g (range 490–3,150) compared with 27 weeks (23–31) and 900 g (370–2,460) in those with BPD. The region-specific crude rate of BPD ranged from 10.2% (Italian region) to 24.8% (UK Northern region). Maternal hypertension, immaturity, male gender, small for gestational age, Apgar <7 and region of care were associated with an increased incidence of BPD on multivariate analysis. Conclusion: A wide variability of BPD between European regions may be explained by different local practices; the strongest association however was with degree of immaturity.

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Section: Methodsmentioning

confidence: 99%

Rates of Bronchopulmonary Dysplasia in Very Preterm Neonates in Europe: Results from the MOSAIC Cohort

Gortner

Misselwitz²,

Milligan³

et al. 2010

Neonatology

Self Cite

117

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“…Esse resultado condiz com o baixo emprego de surfactante observado nos nascimentos com peso inferior a 1.000g. Alguns países europeus reservam condutas mais pró-ativas aos recém-nascidos de maior viabilidade 2,18,24,25 , porém cabe comentar que, nesses locais, há parâmetros definidos para o emprego de tais condutas e há participação de familiares no processo de definição desses parâ-metros 26,27 .…”

Section: Introductionunclassified

Sobrevida e fatores de risco para mortalidade neonatal em uma coorte de nascidos vivos de muito baixo peso ao nascer, na Região Sul do Município de São Paulo, Brasil

et al. 2011

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Estudos populacionais sobre mortalidade neonatal de nascimentos de muito baixo peso ao nascer contribuem para identificar sua complexa rede de fatores de risco. Foi estudada uma coorte de 213 recém-nascidos com peso inferior a 1.500g (112 óbitos neonatais e 101 sobreviventes) na Região Sul do Município de São Paulo, Brasil, em 2000/2001. Foram realizadas entrevistas domiciliares e obtidos dados de prontuários hospitalares. Foi realizada análise de sobrevida e empregada regressão múltipla de Cox. A elevada mortalidade na sala de parto, no primeiro dia de vida e ausência de sobreviventes < 700g dos nascimentos < 1.000g e com menos de 28 semanas sugere que condutas mais ativas destinam-se a nascituros de maior viabilidade. Mães residentes em favela, com história anterior de cesárea e aborto provocado, adolescentes, com sangramento vaginal e ausência de pré-natal aumentaram o risco de óbito neonatal. Partos cesarianos e internação em berçários mostraram efeito protetor. O peso ao nascer abaixo de 1.000g e Apgar menor que 7 foram risco. A elevada mortalidade está associada às condições de vida, características maternas e dos nascimentos e condições assistenciais. A melhoria da atenção pré-natal e ao recém-nascido pode atuar na redução da mortalidade.

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“…There is considerable variation in reported rates, however, depending upon the centre. Among 4213 infants born in 2003 at 24-31 weeks' gestation in 10 different European regions, the rate of BPD (oxygen requirement at 36 weeks' PMA) was anywhere from 10.5% to 21.5% (Zeitlin et al, 2008). A 2010 NICHD Neonatal Research Network report on neonatal outcomes of extremely preterm infants assessed 9575 infants born at extremely low gestational ages (22-28 weeks) and very low birth weights (401-1500 g) at network centers between January 1, December 31, 2007.…”

Section: Epidemiologymentioning

confidence: 99%

Bronchopulmonary Dysplasia: The Role of Oxidative Stress

Lavoie¹,

Mohamed²

2012

Lung Diseases - Selected State of the Art Reviews

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Differences in Rates and Short-term Outcome of Live Births Before 32 Weeks of Gestation in Europe in 2003: Results From the MOSAIC Cohort

Cited by 130 publications

References 43 publications

Rates of Bronchopulmonary Dysplasia in Very Preterm Neonates in Europe: Results from the MOSAIC Cohort

Rates of Bronchopulmonary Dysplasia in Very Preterm Neonates in Europe: Results from the MOSAIC Cohort

Sobrevida e fatores de risco para mortalidade neonatal em uma coorte de nascidos vivos de muito baixo peso ao nascer, na Região Sul do Município de São Paulo, Brasil

Bronchopulmonary Dysplasia: The Role of Oxidative Stress

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