Dietary intake in head and neck irradiated patients with permanent dry mouth symptoms

Bäckström, Inger T.; Funegård, Ulrika; Андерссон, И.; Franzén, Lars; Johansson, Ingegerd

doi:10.1016/0964-1955(95)00023-b

Cited by 41 publications

(23 citation statements)

References 22 publications

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“…Symptoms of dry mouth, which are likely related to a reduced salivary flow rate have been reported to decrease energy intake in irradiated patients (Bäckström et al, 1995) and the elderly (Lovat, 1996). This reduced energy intake may be due to peri-prandial feelings of satiety from reduced palatability of foods and/ or slower oral processing (i.e.…”

Section: Discussionmentioning

confidence: 99%

The effect of hydration status on appetite and energy intake

Corney

Sunderland

James

2014

Journal of Sports Sciences

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This study investigated the effects of hydration status and fluid availability on appetite and energy intake. Sixteen males completed four 24 h trials, visiting the laboratory overnight fasted on two consecutive days. Standardised foods were provided during the 24 h and on day two an ad-libitum semi-solid porridge breakfast was provided. Water intake during the 24 h (0 or 40 mL•kg -1 ) and fluid provision during the ad-libitum breakfast were manipulated so subjects were euhydrated with (EU-F) and without fluid (EU-NF) available at breakfast; and hypohydrated with (HYPO-F) and without fluid (HYPO-NF) available at breakfast. Blood samples (0 and 24 h), urine samples (0-24 h) and subjective responses (0, 24 and 24.5 h) were collected. HYPO trials decreased body mass by ~1.8%. Serum and urine osmolality increased and plasma volume decreased during HYPO trials (P<0.001). Total urine output was greater during EU than HYPO trials (P<0.001). Ad-libitum energy intake was not different between trials: 2658 (938) kJ (EU-F), 2353 (643) kJ (EU-NF),2295 (529) kJ (HYPO-F), 2414 (954) kJ (HYPO-NF), (P=0.131). Fluid intake was ~200 mL greater during HYPO-F than EU-F (P<0.01). There was an interaction effect for thirst (P<0.001), but not hunger or fullness. These results demonstrate that mild hypohydration produced by inadequate fluid intake and fluid availability during eating does not influence ad-libitum energy intake of a semi-solid breakfast, at least in healthy young males.3

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Section: Discussionmentioning

confidence: 99%

The effect of hydration status on appetite and energy intake

Corney

Sunderland

James

2014

Journal of Sports Sciences

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“…Due to the radiation-mediated changes such as mucositis, atrophy of oral mucous membranes, hyposalivation, and taste loss, the diet of irradiated patients shifts to softer, sticky, carbohydraterich foods, with an increase in the frequency of intake-all of which promote caries. The average daily energy intake is about 300 kcal lower in irradiated patients with dry mouth symptoms (Bäckström et al, 1995).…”

Section: (3):199-212 (2003)mentioning

confidence: 99%

“…Several studies have shown that up to 60% of head and neck cancer patients were nutritionally compromised at initial diagnosis (Donaldson and Lenon, 1979;Bassett and Dobie, 1983;Wood et al, 1989;Bäckström et al, 1995;Lees, 1999;Van Bokhorst-van der Schueren et al, 2001). A pre-operative weight loss of 10% of body weight has been reported as a predictive risk factor for major post-operative complications (Van Bokhorst-van der Schueren et al, 1997).…”

Section: Nutritional Statusmentioning

confidence: 99%

Oral Sequelae of Head and Neck Radiotherapy

Vissink

Jansma

Spijkervet

et al. 2003

Critical Reviews in Oral Biology & Medicine

759

512

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In addition to anti-tumor effects, ionizing radiation causes damage in normal tissues located in the radiation portals. Oral complications of radiotherapy in the head and neck region are the result of the deleterious effects of radiation on, e.g., salivary glands, oral mucosa, bone, dentition, masticatory musculature, and temporomandibular joints. The clinical consequences of radiotherapy include mucositis, hyposalivation, taste loss, osteoradionecrosis, radiation caries, and trismus. Mucositis and taste loss are reversible consequences that usually subside early post-irradiation, while hyposalivation is normally irreversible. Furthermore, the risk of developing radiation caries and osteoradionecrosis is a life-long threat. All these consequences form a heavy burden for the patients and have a tremendous impact on their quality of life during and after radiotherapy. In this review, the radiation-induced changes in healthy oral tissues and the resulting clinical consequences are discussed.

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“…Therefore, it is important to alleviate the damage caused by irradiation to the salivary glands. [1][2][3][4][5] In a fundamental study on the alleviation of radiation effects, Abok et al 6 reported that heavy metals are abundant in the secretory granules of acinar cells, and radiation exposure after the egestion of the secretory granules causes relatively less damage. In addition, experiments have been conducted wherein the salivary gland is irradiated after the secretory granules are egested by the use of a neurostimulant.…”

Section: Introductionmentioning

confidence: 99%