Die elektrochemische oxydation aromatischer n-oxide

Flavin model systems. 1. The electrochemistry of 1-hydroxyphenazine and pyocyanine in aprotic solvents

“…The nonaqueous electrochemistry of phenazine and substituted phenazines is of interest because of their use as dye stuffs, the biological importance of some derivatives, and the structural relationship to isoalloxazine and to flavoproteins, flavin mononucleotide (FMN), and flavin adenine dinucleotide (FAD). [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] Because electrochemical studies of flavoproteins, FMN, and FAD are experimentally difficult, investigations often examine simpler model compounds, such as riboflavin, lumiflavin, 3-methyllumiflavin, 10-methylisoalloxazine, 8-quinolinol, and phenazine. Previous studies have noted the deficiencies of these model systems and ambiguities due to disproportionation reactions in aqueous solution.…”