Development of Sustainable Bioprocesses

Heinzle, Elmar; Biwer, Arno P.; Cooney, Charles L.

doi:10.1002/9780470058916

Cited by 132 publications

(155 citation statements)

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“…There has been a wide range of existing and established tools for estimating costs and revenues [42]. Finding and estimating cost and economic related data is less than a challenge compared to environmental life cycle data.…”

Section: Economic Dimension Of Sustainabilitymentioning

confidence: 99%

Advancing Integrated Systems Modelling Framework for Life Cycle Sustainability Assessment

2011

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Abstract:The need for integrated methodological framework for sustainability assessment has been widely discussed and is urgent due to increasingly complex environmental system problems. These problems have impacts on ecosystems and human well-being which represent a threat to economic performance of countries and corporations. Integrated assessment crosses issues; spans spatial and temporal scales; looks forward and backward; and incorporates multi-stakeholder inputs. This study aims to develop an integrated methodology by capitalizing the complementary strengths of different methods used by industrial ecologists and biophysical economists. The computational methodology proposed here is systems perspective, integrative, and holistic approach for sustainability assessment which attempts to link basic science and technology to policy formulation. The framework adopts life cycle thinking methods-LCA, LCC, and SLCA; stakeholders analysis supported by multi-criteria decision analysis (MCDA); and dynamic system modelling. Following Pareto principle, the critical sustainability criteria, indicators and metrics (i.e., hotspots) can be identified and further modelled using system dynamics or agent based modelling and improved by data envelopment analysis (DEA) and sustainability network theory (SNT). The framework is being applied to development of biofuel supply chain networks. The framework can provide new ways of integrating knowledge across the divides between social and natural sciences as well as between critical and problem-solving research. OPEN ACCESSSustainability 2011, 3 470

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Section: Economic Dimension Of Sustainabilitymentioning

confidence: 99%

Advancing Integrated Systems Modelling Framework for Life Cycle Sustainability Assessment

2011

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“…Moreover, antifoam often works upon addition, but the foam build-up will soon ensue as the fermentation progresses. On the other hand, mechanical foam breakers or any mechanical devices are only applicable for a moderately foaming culture as this technique can cause high energy consumption (Heinzle et al, 2006). The simultaneous rhamnolipid production and primary recovery using the foam fractionation system developed in this work was able to address the foaming problem associated with rhamnolipid production without the addition of an antifoam agent.…”

Section: Resultsmentioning

confidence: 89%

Improving Biosurfactant Recovery from Pseudomonas aeruginosa Fermentation

Salleh¹,

Noh²,

Yahya³

2011

Progress in Molecular and Environmental Bioengineering - From Analysis and Modeling to Technology Applications

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“…The most useful tool of this type is the application of isotopic tracer methods. In isotopic tracer techniques there is a substrate in the cells labeled with an easily detectable isotope of a specific atom, normally 14 C , but especially 13 C , stable and non radioactive isotopes, to be detected by Nuclear Magnetic Resonance (NMR).…”

Section: Metabolic Modelingmentioning

confidence: 99%

“…In case of the structured models [12,13] the biotic phase is not any more viewed as a homogenous component, but they provide information about the physiological state of the cells, their composition and regulatory adaptation to the environment. Conforming to this concept the cell mass is structured in several intracellular compounds and functional groups, which are connected to each other and to the environment by fluxes of material and information.…”

Section: Typementioning

confidence: 99%

“…The segregated models [12,13] can describe more complex phenomena like: alterations or disturbances in the physiology and cell metabolism; cells 'morphological differentiation; genome mutations; spatial segregations of growth regions; cells aggregation; mixed cultures (including the competition between two or more species for the same substrate). On the contrary the unstructured and structured models have the limit to consider a homogenous population of cells and only one species in the bioreactor.…”

Section: Typementioning

confidence: 99%

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