Determination of parabens in shampoo using high performance liquid chromatography with amperometric detection on a boron-doped diamond electrode

Martins, Ignez Salas; Carreira, Franciely Cristiani; Canaes, Larissa S.; Campos, Francisco Alberto de Souza; Cruz, Letícia Maria da Silva; Rath, Susanne

doi:10.1016/j.talanta.2011.04.047

Cited by 77 publications

(43 citation statements)

References 29 publications

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“…The reason for this phenomenon can be a decrease of viscosity of the mixed solvent (from 1.322 to 1.061 mPa s for HAc and its mixture with 20 % AN, respectively) and thus the increase of the diffusion coefficient for MP. These observations confirm the results obtained by Martins et al [8] during the anodic oxidation of parabens in aqueous solutions. An addition of AN to HAc causes simultaneously a considerable increase of the specific conductivity, v of the solutions (from 9.2 to.…”

Section: Choice Of the Solution Compositionsupporting

confidence: 93%

“…Esters of p-hydroxybenzoic acid (PHB), commonly known as parabens, are extensively used as preservatives in pharmaceuticals [1][2][3][4], cosmetics [1][2][3][5][6][7][8][9], and foodstuffs [1][2][3][10][11][12][13]. Their molecular structures are shown in Scheme 1.…”

Section: Introductionmentioning

confidence: 99%

“…They were mainly examined to evaluate the optimal conditions for their determination in real samples using electrochemical detectors [8,[29][30][31]. Wang et al [29] suggested a rapid and reliable electrochemical method to determine the total content of parabens in cosmetics on a GC electrode modified with polymers (MIPs) containing MP and PP as dual templates.…”

Section: Introductionmentioning

confidence: 99%

“…These results indicate that only the total content of parabens can be calculated by this electrochemical method. Martins et al [8] applied a boron-doped diamond electrode (BDD) as a sensor to determine parabens in shampoo by the HPLC with amperometric detection using a mobile phase consisting of water disodium phosphate solution and acetonitrile (AN). It has been shown that all parabens investigated are irreversibly oxidized at the same potential of about 0.9 V (vs. Ag/AgCl) and the overall process is diffusion controlled.…”

Section: Introductionmentioning

confidence: 99%

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Anodic oxidation of parabens in acetic acid–acetonitrile solutions

Michałkiewicz

2012

J Appl Electrochem

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The electrochemical properties of esters of p-hydroxybenzoic acid, called parabens, were investigated on a carbon fiber microelectrode and on a glassy carbon macroelectrode in glacial acetic acid containing 20 % acetonitrile (v/v) and sodium acetate as a supporting electrolyte. The anodic oxidation of parabens in this medium proceeds in a single stage giving well-shaped peaks or waves in the same potential region of above 1.0 V (vs. Ag/AgCl). The electrode process was characterized as being quasireversible, diffusion-controlled, and proceeds with the exchange of one electron and one proton. Phenoxyl radicals as products of the electrode process are chemically unstable and participate in the successive irreversible homogenous reactions resulting in electroinactive products (E q C i mechanism). Smaller oxidation potentials for parabens in comparison to such unsaturated fatty acids as oleic, linoleic, and linolenic ones indicate that these compounds can show antioxidative properties. Since parabens are often used as preservatives in many products, the results presented can be found useful in the determination of their total content in real samples.

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Section: Choice Of the Solution Compositionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Anodic oxidation of parabens in acetic acid–acetonitrile solutions

Michałkiewicz

2012

J Appl Electrochem

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“…Several hundreds of reviews [26], [27] and [28] were published on applications of these electrodes in cyclic voltammetry for the analysis of pesticides, herbicides, pharmaceutical products [29], [30] and [31]. The conductive diamond was also used to manufacture electrodes for electrochemical detection in HPLC and flow injection [32], [33], [34], [35], [36], [37] and [38] electrochemical reactions [39].…”

Section: Introductionmentioning

confidence: 99%

Boron doped diamond microelectrodes arrays for electrochemical detection in HPLC

Mahé

Devilliers

Dardoize

2015

Talanta

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To cite this version:Eric Mahé, Didier Devilliers, François Dardoize. Boron doped diamond microelectrodes arrays for electrochemical detection in HPLC. Talanta, Elsevier, 2015, 132, pp.641 -647 Highlights•Boron-doped diamond microelectrodes arrays have been used as sensors for HPLC.•These amperometric sensors have a good signal/noise ratio.•Spacing, disposition and number of the microelectrodes have been studied, as well as influence of flow velocity. AbstractBoron doped diamond microelectrodes arrays (MEA) have been prepared in order to be used as new

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Analysis of parabens in dentifrices and the oral cavity

Park

Jang

Park

et al. 2014

Biomedical Chromatography

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This study analyzed levels of parabens in commercial dentifrices and saliva. HPLC was performed using 35% acetonitrile and measuring absorbance at 254 nm. Thirteen toothpastes and five mouthwashes were analyzed. Of these, volunteers used three toothpastes and two mouthwashes, and levels of parabens were analyzed in saliva and water used for mouth rinsing. In toothpastes, the highest concentrations of methylparaben (MP), propylparaben (PP) and n-butylparaben (nBP) were 1.86, 1.42 and 1.87 mg/g, respectively. In mouthwashes, the highest concentrations of MP and PP were 0.97 and 0.11 mg/mL, respectively. After volunteers used 500 mg toothpaste T-1, which contained 895 µg MP, the first and tenth mouth rinse samples contained means of 64.63 and 1.89 µg MP, respectively. After rinsing the mouth three or five times, 37 µg or 18 µg MP was calculated to remain in the oral cavity, respectively. After using 20 mL mouthwash S-1, which contained 19 mg MP, 1.53 mg MP was calculated to remain in the oral cavity. Immediately after using this mouthwash, the mean salivary concentration of MP was 237 µg/mL. The daily intake of parabens from dentifrices was predicted to be insignificant compared with the intake from food; however, parabens can be ingested from dentifrices.

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Determination of parabens in shampoo using high performance liquid chromatography with amperometric detection on a boron-doped diamond electrode

Cited by 77 publications

References 29 publications

Anodic oxidation of parabens in acetic acid–acetonitrile solutions

Anodic oxidation of parabens in acetic acid–acetonitrile solutions

Boron doped diamond microelectrodes arrays for electrochemical detection in HPLC

Analysis of parabens in dentifrices and the oral cavity

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