Determination of Isoflavon Aglicone in Extract of Soymilk and Tempeh

Fawwaz, Muammar; Natalisnawati, Ayu; Baits, Muzakkir

doi:10.21776/ub.industria.2017.006.03.6

Cited by 11 publications

(12 citation statements)

References 10 publications

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“…Tempeh is a traditional fermented product, which often used Rhizopus oligosporus, R. microsporus, or R. oryzae for its fermentation. Fawwaz, et al 20 show that genistein level in tempeh is 5 times higher compared with soymilk. That finding proves that the fermentation process can release sugar on isoflavones to produce genistein.…”

Section: Discussionmentioning

confidence: 99%

Effect of isoflavone consumptions on the recurrence and survival rate among breast cancer patients: an evidence-based case report

Meilianawati

Manikam

2020

World Nutr J

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Background: isoflavones possess both anti-estrogenic and estrogenic-like properties. Tempeh is a traditional dish from Indonesia which rich in isoflavone content. It remains controversial whether women diagnosed with breast cancer should be advised to avoid or increase the intake of food products that contain isoflavone to improve survival.Objective: to identify the association between post-diagnosis isoflavone food consumption with the recurrence and survival rate among women with breast cancer. Methods: the search was conducted with advanced searching on PubMed, Cochrane, Scopus, and ProQuest according to the clinical question. The screening of title and abstract using inclusion and exclusion criteria, filtering double, and reading full text led to six useful articles. The selected studies were critically appraised for validity, importance, and applicability.Results: five prospective cohort studies and one meta-analysis were found with comparable validity. Women at the high level of isoflavone intake (>10 mg/day) had a significant reduction in the risk of recurrence and mortality of breast cancer.Conclusion: isoflavone food intake is associated with better survival, low recurrence, and low mortality among breast cancer patients.

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Section: Discussionmentioning

confidence: 99%

Effect of isoflavone consumptions on the recurrence and survival rate among breast cancer patients: an evidence-based case report

Meilianawati

Manikam

2020

World Nutr J

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“…37 Isoflavon bentuk aglikon, terutama genistein menunjukkan aktivitas antioksidan paling tinggi. 38 Genistein diketahui memiliki efek protektif terhadap kerusakan sel 𝛽 pankreas serta memperbaiki sekresi insulin dan kadar glukosa darah pada tikus diabetes yang diinduksi STZ. 35 Genistein meningkatkan uptake glukosa melalui aktivasi adenosine monophosphate-activated protein kinase (AMPK) yang menginduksi translokasi GLUT4.…”

Section: Berat Badanunclassified

PENGARUH PEMBERIAN SARI EDAMAME (Glycine max (L.) Merrill) TERHADAP KADAR ASAM URAT TIKUS WISTAR JANTAN DIABETES

Mardiana

Ardiaria

Ayustaningwarno

et al. 2022

Journal of Nutrition College

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Latar Belakang: Beberapa penelitian menunjukkan terdapat peningkatan risiko hiperurisemia pada pasien diabetes melitus tipe 2. Faktor yang mempengaruhi hiperurismeia yaitu penurunan ekskresi asam urat dan peningkatan produksi asam urat. Asupan antioksidan dan purin merupakan faktor yang mempengaruhi produksi asam urat. Edamame berpotensi menurunkan risiko hiperurisemia karena mengandung isoflavon tinggi dan purin yang sangat rendahTujuan: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian sari edamame terhadap kadar asam urat tikus wistar diabetes.Metode: Penelitian ini merupakan penelitian true experimental dengan pre-post test control design. Sampel penelitian ini adalah 24 ekor tikus wistar jantan yang dibagi dalam 4 kelompok dan masing-masing terdiri atas 6 ekor tikus [K (-); K (+); P1; P2]. Kelompok K (+), P1, dan P2 diinduksi Streptozotocin 45 mg/kgBB dan Nicotinamide 110 mg/kgBB . Kelompok P1 dan P2 diberikan intervensi sari edamame dengan dosis 1,8 ml/hari dan 3,6 ml/hari selama 28 hari. Pengambilan sampel darah melalui plexus retroorbitalis. Pemeriksaan kadar asam urat menggunakan metode FS TBHBA. Perbedaan kadar asam urat pre-post intervensi dianalisis menggunakan uji paired t test. Perbedaan antar kelompok dianalisis menggunakan uji Kruskal-Wallis dengan uji lanjut Mann-Whitney.Hasil: Pemberian sari edamame selama 28 hari menunjukkan perbedaan kadar asam urat yang signifikan (p<0,05). Kelompok P1 dan P2 mengalami penurunan kadar asam urat signifikan sebesar 4,62+0,28 mg/dl dan 5,43+0,15 mg/dl. Kelompok P1 dan P2 memiliki perbedaan kadar asam urat yang signifikan dibandingkan kelompok K(-) dan K(+).Simpulan: Pemberian sari edamame dosis 1,8 ml/hari dan 3,6 ml/hari secara efektif menurunkan kadar asam urat tikus wistar diabetes.

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“…14 Kandungan isoflavon dalam tempe 5 kali lebih besar bila dibandingkan dengan susu kedelai. 15 " Penelitian menunjukkan bahwa tempe memiliki kandungan genistein, daidzein, asam γ-aminobutyric (GABA) tinggi, betasitosterol, asam glutamate, asam amino bebas dan S peptida lainnya yang dapat mencegah penyakit kardiovaskuler. 16,9 Formula supromin dibuat berdasarkan kebutuhan gizi penderita strok, terbuat dari bahan-bahan yang direkomendasikan bagi penderita strok dengan harga yang relative terjangkau.…”

Section: Pendahuluanunclassified

Efektifitas Formula “Supromin” (Makanan Enteral Dari Tempe) Terhadap Perbaikan Kadar Albumin Dan Kolesterol Pasien Strok

Sulistiyaningsih

Wiboworini

Nurwati

2022

Gizindo

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Stroke has been a leading cause of death in Indonesia based on Riskesdas data in 2018, it is known that Sroke's prevalence increased from 7 per million to 10.9 per million. Patients with acute stroke were found to be lacking in protein energy by 16.3 percent - 35 percent. "Supromin" is a modified enteral food made from tempeh, skim milk, and egg white which is expected to increase food intake and improve the lipid profile of stroke patients. This study aims to analyze the effect of "supromin" and commercial formulas on albumin and cholesterol levels in stroke patients. This experimental study employed the pre-test and post-test control group design. Respondents were selected using consecutive random sampling. Data were analyzed using paired – t-tests. After 10 days of treatment, there was an increase in albumin levels of 0.17+0.29 mg/dL (p=0.069) in the group receiving the supromin formula and a decrease in albumin levels of 0.08+0.08 mg/dL (p=0.006) in the group receiving the commercial formula. Supromin formula is effective in reducing cholesterol level 16.58+18.31 mg/dL (p = 0.009). Giving supromin formula increases albumin levels and significantly lowers cholesterol levels in stroke patients. It is necessary to consider the provision of the supromin formula for a longer period.

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Determination of Isoflavon Aglicone in Extract of Soymilk and Tempeh

Cited by 11 publications

References 10 publications

Effect of isoflavone consumptions on the recurrence and survival rate among breast cancer patients: an evidence-based case report

Effect of isoflavone consumptions on the recurrence and survival rate among breast cancer patients: an evidence-based case report

PENGARUH PEMBERIAN SARI EDAMAME (Glycine max (L.) Merrill) TERHADAP KADAR ASAM URAT TIKUS WISTAR JANTAN DIABETES

Efektifitas Formula “Supromin” (Makanan Enteral Dari Tempe) Terhadap Perbaikan Kadar Albumin Dan Kolesterol Pasien Strok

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