Demonstration of Split Products of Fibrinogen in the Blood of Normal Newborns

Bonifaci, E; Baggio, Paolo; Gravina, Emanuele Poliana Lawall

doi:10.1159/000240088

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1969

1991

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Cited by 14 publications

(3 citation statements)

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“…Bonifaci, Baggio, and Gravina (1968), using the relatively insensitive and semiquantitative technique of immunoelectrophoresis, were able to show the presence of FDP in 7 out of 15 normal newborns at the twelfth hour, but were unable to detect them thereafter. More recently Stiehm and Clatanoff (1969) …”

Section: Discussionmentioning

confidence: 90%

Fibrin-fibrinogen degradation products in sera of normal infants and children.

Uttley¹,

Allan²,

Cash³

1969

Archives of Disease in Childhood

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Section: Discussionmentioning

confidence: 90%

Fibrin-fibrinogen degradation products in sera of normal infants and children.

Uttley¹,

Allan²,

Cash³

1969

Archives of Disease in Childhood

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“…Their significance in the newborn and preterm infant is still not clear at this time. All infants, including full-term babies, show in creased fibrinolytic activity shortly after birth [7], and there is con flicting evidence regarding normal levels of fibrin split products in the newborn [8,24,25].…”

Section: Discussionmentioning

confidence: 99%

Hypercoagulability in Premature Infants with Special Reference to the Respiratory Distress Syndrome and Hemorrhage

Markarian¹,

Githens²,

Rosenblut³

et al. 1971

Neonatology

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“…At this age the euglobulin lysis time fell in all cases within the normal range for adults and no measurable amounts of fibrinolytic split products could be demonstrated (1,5,10,20). It seems, there fore, that the abnormality of thrombin time is not corrected as FDP disappear from the serum.…”

Section: Discussionmentioning

confidence: 75%

Fibrinolysis, Fibrinogen and Thrombin Time in Newborns

Hrodek¹,

Mydlil²,

Housková³

et al. 1976

Neonatology

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Comparative experiments were made on blood samples collected with and without addition of a potent fribrinolysis-blocking agent in newborn infants aged up to 12 h. Prevention of the in vitro fibrinolysis resulted in a diminished frequency of an abnormal euglobulin clot lysis time, but there was no significant difference in fibrinogen levels and in the frequency and degree of a prolonged thrombin time. These results indicate that the prolongation of thrombin time in newborn infants cannot be prevented by blocking the in vitro fibrinolysis. The significance of these findings is discussed with regard to the possible existence of an abnormal ‘fetal fibrinogen’.

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Demonstration of Split Products of Fibrinogen in the Blood of Normal Newborns

Cited by 14 publications

References 5 publications

Fibrin-fibrinogen degradation products in sera of normal infants and children.

Fibrin-fibrinogen degradation products in sera of normal infants and children.

Hypercoagulability in Premature Infants with Special Reference to the Respiratory Distress Syndrome and Hemorrhage

Fibrinolysis, Fibrinogen and Thrombin Time in Newborns

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