Although previous studies have shown the benefits of exercise training in hemodialysis patients, little is known about the effects of long-term of exercise program on these patients. We investigated the effects and the safety of long-term aerobic training and the effects of detraining on functional capacity and quality of life in hemodialysis patients. Ten patients were allocated to two groups: training and detraining. The training group completed at least 30 months of aerobic training, and the detraining group completed at least 20 months and then discontinued the training for at least 10 months. The outcomes were analyzed at baseline, after 3 months of aerobic training and at the 30-month follow-up. The training and detraining groups performed 37 (5.5) and 24 (3.0) months of aerobic training, respectively. The detraining group discontinued the training for 11.0 (2.0) months. After 3 months of aerobic training, six-minute walking test distance increased significantly in both groups (training group = 569 (287.8) vs 635.5 (277.0) m, p = 0.04; detraining group = 454.5 (72.3) vs 515.0 (91.8) m, p = 0.04). There was no significant difference in the six-minute walking test distance in the training group (576.5 (182.5), p  >  0.05) and a significant decrease (436.2 (89.6) m, p = 0.04) in the detraining group at the follow-up compared to the third month of aerobic training. No significant difference was observed in quality of life during the study. No complications were found during the protocol of the exercise. These results suggest that long-term aerobic training is safe and can maintain functional capacity in hemodialysis patients. In contrast, detraining can result in loss of functional capacity in these patients.

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A obesidade está associada a várias complicações e maior risco de mortalidade. A mudança no estilo de vida é uma das intervenções fundamentais para melhora do quadro clínico desses pacientes, sendo a prática de exercícios físicos um dos seus componentes. O objetivo do presente estudo foi realizar uma revisão de literatura sobre o exercício físico em adultos e idosos com obesidade, descrevendo os principais programas de exercício, a forma adequada de prescrição e os benefícios da sua prática regular. O exercício aeróbico é a modalidade mais indicada para a perda de peso e está associado com maiores benefícios para estes pacientes. Adicionalmente, tem sido preconizado a realização de exercício resistido como terapia complementar. Para alcançar os benefícios da prática regular de exercício físico, a literatura sugere que sejam realizados exercícios aeróbicos de moderada a alta intensidade por no mínimo 150 minutos por semana e quando possível acrescentar o treinamento resistido, 2 a 3 vezes por semana, com carga de 60-70% de uma repetição máxima. Portanto, a prescrição individualizada de exercício físico para pacientes com obesidade representa uma estratégia eficaz para a redução do peso, tratamento e controle dos fatores de risco cardiovasculares, além de promover benefícios na sintomatologia e em outras complicações.

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To evaluate the factors associated with functional capacity in patients with chronic kidney disease (CKD). All patients were submitted to six-minute walk test (6MWT), 10-repetition sit-to-stand test (STS-10) and SF-36 health-related quality of life questionnaire (HRQoL). Patients with functional capacity ≥80% exhibited higher education level, family income, body mass index, estimated glomerular filtration rate, and lower age and STS-10 time. Multiple linear regression showed that gender, age, family income, chronic kidney disease stage, STS-10 time, and physical component summary of HRQoL were significantly associated with the 6MWT distance. Functional capacity was significantly associated with gender, age, family income, CKD stage, STS-10 time, and physical component of HRQoL. The progression of CKD has an impact on the decrease in functional capacity in these patients.

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