Das bilaterale Hypernephrom

Sparwasser, C.; Bach, D; Sparwasser, H.; Altwein, J. E.

doi:10.1055/s-2008-1062661

Cited by 10 publications

(4 citation statements)

References 11 publications

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“…This observation is supported by the biological be havior of the RCC since multifocal and bilateral disease is reported to range from 0.5 to 5% [5,7,16]. In our study, 35 patients had bilateral disease; in 18 cases the tumor occurred synchronously and in 17 asynchronous ly.…”

Section: Discussionsupporting

confidence: 70%

Results after Organ-Preserving Surgery for Renal Cell Carcinoma

Rauchenwald²,

Zechner³

et al. 1990

Eur Urol

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Section: Discussionsupporting

confidence: 70%

Results after Organ-Preserving Surgery for Renal Cell Carcinoma

Rauchenwald²,

Zechner³

et al. 1990

Eur Urol

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“…Of our own patients, 23 exhibited bilateral tumors, either synchronously or metachronously, in one case 15 years after the first operation. The major concern regarding the use of organ-preserving surgery for renal cell carcinoma in patients with a normal contralateral kidney is the risk of multifocality, for which an incidence of 0.5 to 5% is reported in the literature [2,6,10,22]. Excluded from this argumentation are patients with von Hippel-Lindau's disease, of whom 75°7o have bilateral tumors [9] and in whom multiple recurrent lesions are common.…”

Section: Discussionmentioning

confidence: 99%

Parenchyma-sparing surgery for renal tumors

Stöckle¹,

Thüroff²,

Störkel³

et al. 1991

World J Urol

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Between 1969Between und 1989 conservative surgery for kidney tumors was performed in 123 patients. In 49 patients there was an imperative indication for a parenchyma-sparing operation because nephrectomy would have made dialysis obligatory. Thirty-five of these 49 patients show no signs of tumor progression after a mean follow-up of 4.5 years. Known metastases were present in 3 of 6 patients who died as a result of their tumors. In two patients there was a recurrence after 1 and 5 years, respectively, requiring a second organ-preserving operation. In one further patient we suspect that multiple small tumor lesions may be present 2 years after the first operation. In 74 patients with a healthy contralateral kidney the tumor was enucleated by choice (elective indication). Sixty-eight of these 74 patients show no signs of tumor progression after a mean follow-up period of 3.3 years. One patient died from tumor metastases. Two patients had tumor recurrence, requiring nephrectomy and enucleation, respectively. Fifty-seven enucleated tumors were available for image analysis DNA cytometry. Only the two patients with a hypertriploid tumor died from their cancer.Until now radical nephrectomy has been regarded as standard therapy for non-metastasized renal cell carcinoma [15,18,21]. This operation has been accepted because of its theorized advantage of more complete resection. A parenchyma-sparing operation has only been performed on patients in whom radical nephrectomy would result in renal failure requiring hemodialysis (imperative indication), such as those with a single kidney, bilateral tumors, dysfunctional contralateral kidney or chronic renal failure. However, the widely used partial nephrectomy in these instances may result, in certain cases, in insufficient residual renal parenchyma [14]. Simple enucleation of the tumor, together with a small surrounding margin of normal renal tissue, is an alternative technique to this * To whom correspondence should be addressed approach. The surprisingly good prognosis of patients, which were treated by enucleation in the imperative group [1], encouraged us over the past 9 years to perform parenchyma-sparing operations also on patients with small peripheral tumors and normal contralateral kidneys (elective indication). In addition, these small and mostly asymptomatic kidney tumors, which only a few years ago were rarely diagnosed, are being detected more frequently by ultrasound. Thus, the incidence of asymptomatic renal tumors increased from 10% in 1978 to 70°70 in 1989, while the classic symptoms of flank pain, hematuria and palpable mass were found in less than 10% of the cases, Here we present the operative technique, complications, patient outcome and preliminary results of image analysis DNA cytometry. Between 1969 and, conservative surgery of kidney tumors was performed in 123 patients. Conservative surgery was imperative for 49 of the patients (18 female, 31 male) aged 38 to 77 years (average age 59 years). A total of 23 patients had metachronous or synchronous bila...

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“…68 Dabei wären sogar im Bebauungsplan festgesetzte stoff bezogene Grenzwerte realisierbar . 69 Ingold/schwarz, Klimaschutzelemente der Bauleitplanung soweit ein Verbot oder eine Verwendungsbeschränkung von heizstoffen in frage steht, stellen sich jedoch rechtliche Probleme hinsichtlich der Vereinbarkeit mit den Vorgaben des Immissionsschutzrechts und des Gemeinschaftsrechts:…”

Section: Festsetzungsmöglichkeitenunclassified

Klimaschutzelemente der Bauleitplanung

Ingold

Schwarz²

2010

NuR

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Der Beitrag thematisiert den Rechtsrahmen für ein Konzept klimaschützender Stadterneuerung durch die Bauleitplanung. Dazu wird systematisch der planungsrechtliche status quo für Klimaschutzmaßnahmen durch die Bauleitplanung vorgestellt. Nach einer Einleitung (I.) soll dabei zunächst die allgemeine Verankerung von Belangen des Klimaschutzes in der Bauleitplanung fokussiert werden (II.), bevor die spezifischen Handlungsformen des Flächen-nutzungsplans (III.), des Bebauungsplans (IV.) und des städtebau-lichen Vertrags (V.) eingehender auf ihre Beiträge zur klimaschüt-zenden Stadterneuerung betrachtet werden.

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Das bilaterale Hypernephrom

Cited by 10 publications

References 11 publications

Results after Organ-Preserving Surgery for Renal Cell Carcinoma

Results after Organ-Preserving Surgery for Renal Cell Carcinoma

Parenchyma-sparing surgery for renal tumors

Klimaschutzelemente der Bauleitplanung

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