Cutaneous horn malignant melanoma

Abstract

A 73-year-old Japanese woman presented with cutaneous horn on the right cheek. The resected tumor was 9 mm in diameter, with 14 mm protrusion, and showed exophytic growth with marked papillomatosis. Histopathology showed proliferation of atypical melanocytes with melanin pigments in the epidermis and dermis under the cutaneous horn. These cells were confined to the base of the cutaneous horn, and did not spread to the surrounding epidermis. The final diagnosis was cutaneous horn malignant melanoma. This pathological entity is considered a specific form of verrucous melanoma, and might be added to the list of cutaneous horn-forming lesions.

A Rare Sweat Gland Tumour- Immunohistochemical Features

“…The sweat glands are composed of 3 segments: the intraepidermal(eccrine)/intrainfundibular (apocrine) duct, the intradermal duct, and the secretory portion. The secretory portion of eccrine glands has a narrow tubular structure composed of pale inner secretory cells and outer myoepithelial cells, whereas apocrine glands shows large tubules composed of eosinophilic secretory cells and peripheral myoepithelial cells [1].…”

Verrucous Melanoma Presenting as a Cutaneous Horn

“…2 Clinically, it is often a plateau or dome-shaped, uniformly pigmented lesion with a verrucous keratotic surface. 2,4 It most commonly presents in women and favors the extremities. 5 This variant accounts for up to 3% of melanomas.…”

Cutaneous malignancies simulating seborrheic keratoses: An underappreciated phenomenon?

“…Verrucous melanoma is notorious for being misdiagnosed as SK clinically . Melanoma can also cause epidermal changes including acanthosis, hyperkeratosis and cutaneous horn formations, which are all features contributing to melanoma's resemblance to SK …”