A Rare Sweat Gland Tumour- Immunohistochemical Features

Prodea, Mihaela-Cristina; Şandru, Florica; Carpenco, Ecaterina; Gaje, Pușa Nela; Horhat, Ioana Delia; Ceauşu, Raluca Amalia; Mederle, N.; Mederle, Ovidiu Alexandru

doi:10.37358/rc.19.5.7233

Cited by 4 publications

(5 citation statements)

References 6 publications

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“…Increasing evidence show a promotion of cancer progression through perturbed estrogen signaling. The differential expression of ERα and ERβ in cancer cells supports the concept that the two ER subtypes have contrasting functions in the essential fundamentals of cancer biology [29].…”

Section: Hormones and Melanomasupporting

confidence: 56%

The Evaluation of Estrogen Receptor β as a Potential Prognosis Factor in Melanoma

2020

Rev.Chim.

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Differences across sexes in cutaneous melanoma incidence, metastatic pathways and disease outcome are consistently observed, with women having a significant survival advantage compared with men. This suggests that gender could play a role as a prognostic indicator through sex hormone signaling, but the mechanism is still unclear. This article focuses on available literature data concerning the influence of estrogen receptor beta (ERβ) expression as a host-related biological protective factor for female patients with melanoma. Furthermore, it highlights the potential role of estrogen receptor beta (ERβ) as a prognostic biologic marker in cutaneous melanoma. Keywords: melanoma, sex, hormone receptors, estrogen receptor β

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Section: Hormones and Melanomasupporting

confidence: 56%

The Evaluation of Estrogen Receptor β as a Potential Prognosis Factor in Melanoma

2020

Rev.Chim.

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“…Chim.1949 Rev. Chim., 71 Some studies have reported high blood concentrations of lead in women with unexplained infertility, while other studies observed reduced fertility and an increased risk of spontaneous abortion in case of mercury exposure among dental health care workers [51,61].…”

Section: Heavy Metalsmentioning

confidence: 99%

“…A major source of human exposure to PCB is the consumption of contaminated fish, cheese, butter, or fatty meats such as pork and beef [70,71].…”

Section: Polychlorinated Biphenyls (Pcb)mentioning

confidence: 99%

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The Impact of Endocrine-Disrupting Chemicals on Female Fertility

Petca¹,

Măru²,

Dumitrașcu³

et al. 2020

Rev. Chim.

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Nowadays, infertility is a prevalent problem among couples. Exposure to endocrine-disrupting chemicals (EDCs) may influence the female reproductive outcomes through multiple mechanisms, being one of the important causes of infertility. These compounds may interfere with some fertility and fecundity markers, leading to increased time to pregnancy, increased risk of spontaneous abortion, shorter menstrual cycles, early age at menopause, anovulation or delayed ovulation, smaller preovulatory follicles, increased serum FSH, decreased synthesis of estradiol and progesterone, low plasma levels of anti-Mullerian hormone and decreased antral follicle count. Endocrine-disrupting chemicals may also impair in vitro fertilization outcomes, being responsible for: a lower probability of implantation, reduced fertilization rates, diminished probability of clinical pregnancy, and near term pregnancies after in vitro fertilization. Another mechanism of altering the female reproductive function is through the disorders induced by EDCs, such as polycystic ovary syndrome, uterine fibroids, and endometriosis. Those conditions may finally lead to infertility.

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“…Frequently, practiciens use the combination of benzoyl peroxide with topical or oral antibiotics that decreases the emergence of antibiotic resistant bacteria. Therefore, use of benzoyl peroxide is recommended in patients that are receiving antibiotic therapy (34,35).…”

Section: Acne Treatmentmentioning

confidence: 99%

Treatment of acne vulgaris in relation to its etiopathogenesis

Şandru¹,

Dumitrașcu²,

Stănescu³

et al. 2019

Ro J Med Pract.

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Acne vulgaris represent a frequent cutaneous disease manifested by chronic or recurrent development of papules, pustules, or nodules at the level of the face, neck, proximal upper extremities or trunk. The pathogenesis of acne vulgaris includes the interaction of multiple factors that lead to the development of comedones and inflammation. Although acne vulgaris dosen't represent a disease that is physically disabling, its psychologic impact can be striking, contributing to anxiety, low self-esteem and depression. As a result of all these, is a big demand for effective therapies for ane vulgaris. The pathogenesis and the treatment for each pathogenic cause of acne vulgaris will be reviewed here. Topical retinoids have a good influence for both comedonal (non-inflammatory) and inflammatory acne and should be included in the initial management of most of the patients. The efficacy of topical retinoids for inflammatory acne may be due to a combination of the intrinsic anti-inflammatory properties of the topical retinoids and their ability in the prevention of the formation of microcomedones.

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A Rare Sweat Gland Tumour- Immunohistochemical Features

Cited by 4 publications

References 6 publications

The Evaluation of Estrogen Receptor β as a Potential Prognosis Factor in Melanoma

The Evaluation of Estrogen Receptor β as a Potential Prognosis Factor in Melanoma

The Impact of Endocrine-Disrupting Chemicals on Female Fertility

Treatment of acne vulgaris in relation to its etiopathogenesis

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