CotA laccase from Bacillus licheniformis ZOM-1 effectively degrades zearalenone, aflatoxin B1 and alternariol

Sun, Fan; Yu, Dianzhen; Zhou, Hu; Lin, Huikang; Zheng, Yufeng; Wu, Aibo

doi:10.1016/j.foodcont.2022.109472

Cited by 32 publications

(28 citation statements)

References 33 publications

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“…The highest degradation rate of AFB 1 was 86.78% for AttM (Figure C). These results indicate that AttM had a high degradation activity under alkaline conditions at 80 °C, which is consistent with the results of Sun et al…”

Section: Results and Discussionsupporting

confidence: 93%

“…The highest degradation rate of AFB 1 was 86.78% for AttM (Figure 5C). These results indicate that AttM had a high degradation activity under alkaline conditions at 80 °C, which is consistent with the results of Sun et al 4 Enzymatic biodegradation can transform aflatoxin structures into less toxic or nontoxic forms. A wide range of microorganisms, including bacteria, actinobacteria, and filamentous fungi, have been identified as sources of several aflatoxindegrading enzymes, which have been isolated and purified.…”

Section: ■ Results and Discussionsupporting

confidence: 92%

“…These deleterious consequences of mycotoxin exposure pose considerable risks to public health and have far-reaching ramifications for the agricultural sectors on a global scale. 4 Currently, the main mycotoxins of concern in various food commodities include aflatoxins, ochratoxin A (OTA), zearalenone (ZEN), and deoxynivalenol (DON). Monitoring and controlling the levels of these mycotoxins is crucial to ensure food safety and protect consumers from the adverse health effects associated with their ingestion.…”

Section: ■ Introductionmentioning

confidence: 99%

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Mining Lactonase Gene from Aflatoxin B₁-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Cheng,

Wu,

Zhang

et al. 2023

J. Agric. Food Chem.

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Section: Results and Discussionsupporting

confidence: 93%

Section: ■ Results and Discussionsupporting

confidence: 92%

Section: ■ Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mining Lactonase Gene from Aflatoxin B₁-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Cheng,

Wu,

Zhang

et al. 2023

J. Agric. Food Chem.

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“…For example, peroxidase extracted from horseradish has been shown to effectively reduce AOH levels in tomatoes ( Tittlemier et al., 2020 ). Glucose oxidase produced by Aspergillus niger has been shown to reduce AOH levels in apples ( Sun et al., 2023 ).…”

Section: Management Of Patulin and Alternaria Myco...mentioning

confidence: 99%

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Bacha

Nie

et al. 2023

Front. Plant Sci.

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Mycotoxins are toxic secondary metabolites produced by certain fungi, which can contaminate various food commodities, including fruits and their derived products. Patulin and Alternaria toxins are among the most commonly encountered mycotoxins in fruit and their derived products. In this review, the sources, toxicity, and regulations related to these mycotoxins, as well as their detection and mitigation strategies are widely discussed. Patulin is a mycotoxin produced mainly by the fungal genera Penicillium, Aspergillus, and Byssochlamys. Alternaria toxins, produced by fungi in the Alternaria genus, are another common group of mycotoxins found in fruits and fruit products. The most prevalent Alternaria toxins are alternariol (AOH) and alternariol monomethyl ether (AME). These mycotoxins are of concern due to their potential negative effects on human health. Ingesting fruits contaminated with these mycotoxins can cause acute and chronic health problems. Detection of patulin and Alternaria toxins in fruit and their derived products can be challenging due to their low concentrations and the complexity of the food matrices. Common analytical methods, good agricultural practices, and contamination monitoring of these mycotoxins are important for safe consumption of fruits and derived products. And Future research will continue to explore new methods for detecting and managing these mycotoxins, with the ultimate goal of ensuring the safety and quality of fruits and derived product supply.

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“…Bacillus licheniformis is capable of producing a very broad spectrum of enzymes, which in turn are able to fully exploit their biocatalytic function in industries such as food manufacturing. For example, CotA laccase from B. licheniformis ZOM-1 can degrade the mycotoxin in food or feed [36], alanine aminopeptidase from B. licheniformis E7 can efficiently hydrolyses soy protein [37]. Usually, two common strategies can be used to obtain active enzymes with high quality functions in B. licheniformis.…”

Section: Functional Enzymesmentioning

confidence: 99%

Recent biotechnological advances and future prospective of Bacillus licheniformis as microbial cell factories

Zhang

Shi

et al. 2023

Syst Microbiol and Biomanuf

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Bacillus licheniformis is a characteristic Gram-positive bacterium originally found in soil. This microorganism has long been utilised as a workhorse for production of industrial enzymes or high value-added chemicals. With ever-increasing understanding on this strain and the maturation of the genetic technique, important advances have recently been made in developing B. licheniformis as an excellent chassis cell for synthetic biology. Here, we provide an overview of updated understanding on genome information, anaerobic metabolism, industrial applications of this strain. The state-of-art B. licheniformis genetics, especially its synthetic biology advances in biosensor, expression system and artificial metabolic pathways are illustrated. Finally, perspectives are offered for the limitations and challenges to be addressed to improve B. licheniformis as microbial cell factories.

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CotA laccase from Bacillus licheniformis ZOM-1 effectively degrades zearalenone, aflatoxin B1 and alternariol

Cited by 32 publications

References 33 publications

Mining Lactonase Gene from Aflatoxin B₁-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Mining Lactonase Gene from Aflatoxin B₁-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Recent biotechnological advances and future prospective of Bacillus licheniformis as microbial cell factories

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CotA laccase from Bacillus licheniformis ZOM-1 effectively degrades zearalenone, aflatoxin B1 and alternariol

Cited by 32 publications

References 33 publications

Mining Lactonase Gene from Aflatoxin B1-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Mining Lactonase Gene from Aflatoxin B1-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Recent biotechnological advances and future prospective of Bacillus licheniformis as microbial cell factories

Contact Info

Product

Resources

About

Mining Lactonase Gene from Aflatoxin B₁-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme

Mining Lactonase Gene from Aflatoxin B₁-Degrading Strain Bacillus megaterium and Degrading Properties of the Recombinant Enzyme