Coriander (Coriandrum sativum L.) seed oil improves plasma lipid profile in rats fed a diet containing cholesterol

Ramadan, Mohamed Fawzy; Amer, Mohammed; Awad, Ashraf

doi:10.1007/s00217-008-0833-y

Cited by 56 publications

(47 citation statements)

References 52 publications

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“…LDL carries cholesterol from the liver to the peripheral cells and smooth muscle cells of the arteries. The rise in LDL may cause a deposition of cholesterol in the arteries and aorta and hence is bad for health and a direct risk factor for CHD (Ramadan et al, 2008a). The accumulation of LDL within the arterial walls appears to play a crucial role in the initiation and progression of atherosclerotic plaque.…”

Section: High and Low Density Lipoprotein Cholesterol (Hdl-and Ldl-chmentioning

confidence: 99%

<i>Physalis peruviana</i> pomace suppresses highcholesterol diet-induced hypercholesterolemia in rats

Ramadan

2012

Grasas y Aceites

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Physalis peruviana (goldenberry) is a promising fruits that can be an ingredient in several functional foods. No reports are available on the effect of the administration of goldenberry pomace on different aspects of the plasma lipid profile in experimental animals. According to the chemical composition of the fruit pomace which includes high levels of bioactive compounds, the hypothesis was that feeding Physalis peruviana pomace may have health-promoting and hypercholesterolemic impacts on rats fed a high cholesterol diet (HCD). Therefore, the objective of this study was to investigate the effect of feeding goldenberry pomace on hypercholesterolemia by analyzing the changes in lipid profiles in HCD fed rats. The chemical composition, lipid profiles (fatty acids, tocopherols and sterols) and phenolic contents of the fruit pomace were determined. Generally, rats fed the fruit pomace showed lower levels of total cholesterol (TC), total triacylglycerol (TAG) and total low density lipoprotein (LDL) cholesterol as well as higher levels of high density lipoprotein (HDL) cholesterol in comparison with animals fed HCD and cholesterol free diets (CFD). Histological examinations of the liver and kidney were also studied. The results demonstrated that goldenberry pomace consumption provides overall beneficial effects on reversing HCD associated detrimental changes.

Physalis peruviana (aguaymanto) es un fruto prometedor que puede ser parte de diferentes alimentos funcionales. No hay datos disponibles sobre el efecto de la administración del orujo de aguaymanto sobre diferentes aspectos del perfil de lipídos plasmáticos en animales de experimentación. De acuerdo con la composición química del orujo de la fruta que incluye altos niveles de compuestos bioactivos, se demostró la hipótesis de que la alimentación con orujo de Physalis peruviana puede tener efectos saludables y sobre la hipercolesterolemia en ratas alimentadas con una dieta alta en colesterol (HCD). Por tanto, el objetivo de este estudio fue investigar el efecto de una alimentación con orujo de Physalis peruviana o sobre la hipercolesterolemia analizando los cambios del perfil lipídico en ratas alimentadas con una dieta alta en colesterol (HCD). Se determinó la composición química, el perfil lipídico (ácidos grasos, tocoferoles y esteroles) y contenido fenólico del orujo de aguaymanto. En términos generales, las ratas alimentadas con orujo de aguaymanto mostraron niveles más bajos de colesterol total (TC), triglicéridos totales (TAG) y lipoproteínas de baja densidad totales, así como superiores niveles de lipoproteínas de alta densidad (HDL) en comparación con los animales alimentados con HCD y con una dieta libre de colesterol (CFD). El examen histológico del hígado y de los riñones fue también realizado. Los resultados demostraron que el consumo de orujo de aguaymanto proporciona efectos beneficiosos generales invirtiendo los cambios perjudiciales asociados a una dieta HCD

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Section: High and Low Density Lipoprotein Cholesterol (Hdl-and Ldl-chmentioning

confidence: 99%

<i>Physalis peruviana</i> pomace suppresses highcholesterol diet-induced hypercholesterolemia in rats

Ramadan

2012

Grasas y Aceites

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“…Söz konusu pozitif etkinin derecesi, bu yağın tüm biyoaktif maddeleri ve antiradikal potansiyeli ile direkt ilişkilidir. Yüksek antioksidatif potansiyele sahip olan kişnişin genel beslenmeye eklenmesinin, özellikle hiperkolesterolemik hastalarda aterosklerozun önlenmesine yardımcı olabileceği öngörülmektedir (75).…”

Section: Kolesterol Düşürücü Etkiunclassified

Kişniş (Coriandrum sativum L.) Üzerine Bir Derleme 1.Giriş Geçmişten beri halk hekimliğinde sıklıkla faydalanılan bitkiler, birçok hastalığın tedavisinde kullanılmıştır. Yaklaşık 12000 tür ve türaltı seviyede takson ile kuzey yarımkürede oldukça zengin bir floraya sahip ülkelerden biri olan Türkiye de de bitkisel kaynaklı ilaçlara başvurulmaya devam edilmektedir. Son zamanlarda, başta Avrupa olmak üzere tüm dünyada bir "doğaya dönüş" akımı başlamıştır. Bunun sonucu olarak da yakın zamana kadar s

Deniz¹,

Yeğenoğlu²,

Şahne³

et al. 2018

mpj

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“…The separation of ST was performed after the saponification of oil according to Ramadan et al (2008). TL (250 mg) were refluxed with 5 mL of ethanolic potassium hydroxide solution (6%, w/v) and a few anti-bumping granules for 60 min.…”

Section: Gas Chromatography (Gc) Analysis Of Sterols (St)mentioning

confidence: 99%

Characterization of fatty acids, bioactive lipids, and radical scavenging activity of Canterbury bells seed oil

2014

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SUMMARY:The aim of this study was to characterize the chemical composition and radical scavenging activity of Canterbury bells (Campanula medium) seed oil. C. medium seeds contained 9.2% extractable oil. The lipid classes, fatty acids, phytosterol and tocopherol composition of C. medium seed oil were determined. The amount of neutral lipids in the oil was the highest, followed by glycolipids and phospholipids. Linoleic and oleic were the main fatty acids. C. medium oil is characterized by high levels of phytosterols and β-sitosterol was the main compound. β-Tocopherol constituted 42.5% of the total tocopherol content followed by γ-tocopherol. The radical scavenging activity (RSA) toward 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and galvinoxyl radicals of C. medium oil were higher than those of extra virgin olive oil. The diverse potential uses of C. medium oil may make this plant industrially important.

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Coriander (Coriandrum sativum L.) seed oil improves plasma lipid profile in rats fed a diet containing cholesterol

Cited by 56 publications

References 52 publications

<i>Physalis peruviana</i> pomace suppresses highcholesterol diet-induced hypercholesterolemia in rats

<i>Physalis peruviana</i> pomace suppresses highcholesterol diet-induced hypercholesterolemia in rats

Characterization of fatty acids, bioactive lipids, and radical scavenging activity of Canterbury bells seed oil

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