Comparing two quantitative methods for studying remineralization of artificial caries

Lo, Edward Chin Man; Zhi, Qinghui; Itthagarun, Anut

doi:10.1016/j.jdent.2010.01.001

Cited by 66 publications

(82 citation statements)

References 24 publications

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“…Moreover, by taking advantage of mineral reference phantoms, precise information of mineral density in teeth can be readily quantified 28) . A recent report concluded that micro-CT has the potential to substitute transverse microradiography (TMR) for in vitro studies on dental caries 29) . A mineral reference phantom was used to determine mineral density in this study.…”

Section: Discussionmentioning

confidence: 99%

<i>In vitro</i> assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization

Miyajima

Ishimoto

et al. 2016

Dent. Mater. J.

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The purpose of this study was to evaluate the ability of a calcium-fluoroaluminosilicate glass-based desensitizer (Nanoseal) to protect against root demineralization in vitro. Nanoseal was applied to human root dentin, which was immersed in acidic buffer for 72 h, or exposed to pH cycling by immersing in distilled water or mineralizing solution for 24 h intermediately during 48 h-acid attack. Demineralization was evaluated by μ-CT, and mineral loss (ML) and lesion depth (LD) were determined from mineral density profiles. ML and LD in all treatment groups were significantly smaller compared with control. The Nanoseal-treated group with pH cycling using mineralizing solution had the lowest ML and LD. Analysis using an EPMA demonstrated calcium and phosphorous were incorporated into the superficial layer of specimens in the Nanoseal-treated groups, suggesting Nanoseal modified the dentin surface, making it resistant to demineralization. Application of Nanoseal is an effective method for protecting root from demineralization.

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Section: Discussionmentioning

confidence: 99%

<i>In vitro</i> assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization

Miyajima

Ishimoto

et al. 2016

Dent. Mater. J.

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“…The varnish material produced a uniform and smooth surface, with occluding of dentinal tubules compared with that in the De group. These characteristics may have been caused by the presence of Si and F ions in S-PRG filler and consequent mineral deposition above the dentin surface and dentinal tubules, leading to much higher integrated values over time 28) . The varnish containing S-PRG fillers was developed for the purpose of producing a material exhibiting both structural strength and ion-releasing ability.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the effects of fluoride-releasing varnish on dentin demineralization using optical coherence tomography

et al. 2014

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Effects of a fluoride-releasing varnish containing surface reaction-type prereacted glass ionomer (S-PRG) filler on dentin demineralization were examined using optical coherence tomography. Bovine incisors that were sliced and treated with undersaturated 0.1 M lactic acid buffer solution (DE group). A thin film of varnish-containing S-PRG filler was applied before demineralization (PRG group). Control was maintained in artificial saliva. Using optical coherence tomography of selected locations on the dentin surface, peak intensity (dB) and width (μm) at 1/e 2 were obtained and integrated values calculated. Although alterations in integrated values were different in each group, there was a slight but not significant increase in those for the control group and a slight but significant increase for the De group. For the PRG group, integrated values were doubled seven days after experiment initiation, followed by a significant increase. Fluoride-releasing varnish containing S-PRG fillers prevented dentin demineralization as detected by optical coherence tomography.

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“…The latter has been a widely accepted method for determining mineral loss or gain in experimentally induced incipient carious lesions 17 and has been used for the comparison and validation of other newly developed caries detection techiniques. [23][24][25] Both of these methods require the tooth to be sectioned as thin as 100 ㎛, which introduces a variation in the results and prevents the longitudinal analysis or assessment of teeth by an examiner.…”

Section: Comprisons With Conventional Methodologiesmentioning

confidence: 99%

“…The LAC describes the extent to which the intensity of an energy beam is reduced as it passes through a specific material. 17 A small LAC value indicates that the material to be tested is relatively transparent, while larger values indicate greater degrees of opacity. Generally, the higher the energy of the radiation and the less dense the material, the lower the corresponding LAC will be.…”

Section: Measurements and Calibrationsmentioning

confidence: 99%

“…13 Although Elliott and Dover are known to be the inventors of the first XMT in 1982, [14][15][16] some authors reported that the simplest prototype of the microtomographic scanner emerged in the 1970s and comprised a pinhole collimator and a single detector. 17 For this first generation microtomographic scanner, energy discriminating detection can easily be used, and the attenuation coefficient can be measured using monochromatic radiation, so the mass density of the material the X-rays have penetrated can be determined. However, the data acquisition time for a single slice can take as long as several hours, which limits its use.…”

Section: Introductionmentioning

confidence: 99%

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Theory of X-ray microcomputed tomography in dental research: application for the caries research

Park

Bae

Chang

et al. 2011

J Korean Acad Conserv Dent

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Caries remains prevalent throughout modern society and is the main disease in the field of dentistry. Although studies of this disease have used diverse methodology, recently, X-ray microtomography has gained popularity as a non-destructive, 3-dimensional (3D) analytical technique, and has several advantages over the conventional methods. According to X-ray source, it is classified as monochromatic or polychromatic with the latter being more widely used due to the high cost of the monochromatic source despite some advantages. The determination of mineral density profiles based on changes in X-ray attenuation is the principle of this method and calibration and image processing procedures are needed for the better image and reproducible measurements. Using this tool, 3D reconstruction is also possible and it enables to visualize the internal structures of dental caries. With the advances in the computer technology, more diverse applications are being studied, such automated caries assessment algorithms.

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Comparing two quantitative methods for studying remineralization of artificial caries

Cited by 66 publications

References 24 publications

<i>In vitro</i> assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization

<i>In vitro</i> assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization

Evaluation of the effects of fluoride-releasing varnish on dentin demineralization using optical coherence tomography

Theory of X-ray microcomputed tomography in dental research: application for the caries research

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