Evaluation of the effects of fluoride-releasing varnish on dentin demineralization using optical coherence tomography

Abstract

Effects of a fluoride-releasing varnish containing surface reaction-type prereacted glass ionomer (S-PRG) filler on dentin demineralization were examined using optical coherence tomography. Bovine incisors that were sliced and treated with undersaturated 0.1 M lactic acid buffer solution (DE group). A thin film of varnish-containing S-PRG filler was applied before demineralization (PRG group). Control was maintained in artificial saliva. Using optical coherence tomography of selected locations on the dentin surface, peak intensity (dB) and width (μm) at 1/e 2 were obtained and integrated values calculated. Although alterations in integrated values were different in each group, there was a slight but not significant increase in those for the control group and a slight but significant increase for the De group. For the PRG group, integrated values were doubled seven days after experiment initiation, followed by a significant increase. Fluoride-releasing varnish containing S-PRG fillers prevented dentin demineralization as detected by optical coherence tomography.

Ions released from a S-PRG filler induces oxidative stress in Candida albicans inhibiting its growth and pathogenicity

“…Surface pre-reacted glass ionomer (S-PRG) filler is an ionreleasing functional bioactive glass where it releases six ions (fluoride, strontium, sodium, aluminum, boric acid, and silicic acid) (Fujimoto et al 2010). During high ion concentrations, ions are recharged and re-released from the S-PRG filler which in turn have various effects: (1) strengthening of tooth structure, (2) inhibition of tooth demineralization, (3) buffering capacity against intraoral acids, and (4) inhibition of dental plaque adhesion on the resin surface (Kaga et al 2014;Kotaku et al 2014;Hotta et al 2014). At present, S-PRG filler has already been used clinically by being incorporated into filling materials, bonding systems, temporary cements, and orthodontic resins (Nakamura et al 2009).…”

Effect of a coating material containing surface reaction-type pre-reacted glass-ionomer filler on prevention of primary enamel demineralization detected by optical coherence tomography

“…The present OCT system (J. Morita Tokyo Mfg. Corp., Saitama, Japan) and methods for data correction were described in a previous report (20). A scanning probe connected to the OCT device was fixed 2 mm from the treated enamel surface, and the width between points where intensity decreased to a value of 1/e 2 was calculated (21).…”

“…Specimens from each group were treated with the same methods and observed with a three-dimensional laser-scanning microscope (LSM; VK-8700; Keyence Corp., Osaka, Japan) (20,21).…”

Silver Diamine Fluoride versus Bioactive Giomer Light-Curing Varnish: An In Vitro Study on Caries Arrest

“…Its bioactive functions are due to the gradual release of multiple ions, including sodium (Na+), aluminum (Al3+), borate (Bo3-), silicate (SiO2-), fluorine (F-), and strontium (Sr2+). Therefore, this technology can be advantageous for dental materials that require the release of fluoride ions for demineralization inhibition [6][7][8][9][10].…”