Comparative evaluation of antimicrobial activity of herbal extracts with 5.25% sodium hypochlorite against multispecies dentinal biofilm

Mistry, Kunjal S; Sanghvi, Zarna; Parmar, Girish; Shah, Samir

doi:10.4103/1658-5984.180619

Cited by 2 publications

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“…NaOCI is considered the gold standard irrigant for endodontic therapy since it meets most of the criteria defining the “ideal” irrigant solution [ 8 , 18 , 19 ]. On the other hand, CHX is a cationic bis-guanide having antibacterial properties [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Current Trends in Irrigation Solution and Adjunct Use During Endodontic Therapy Among Dental Professionals in Jeddah, Saudi Arabia: A Cross-Sectional Study

Alzamzami¹,

Alqurashi²,

Almansour³

et al. 2022

Cureus

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IntroductionChemical irrigation is a crucial component of endodontic therapy, and irrigation adjuncts increase the efficiency of non-surgical root canal system disinfection, reduce microbial loads, and enhance the penetration of irrigants throughout the root canal system. This study aimed to determine the current trends in chemical irrigation and its adjunct use during root canal therapy by general dental practitioners (GDPs) and endodontic specialists in both government and private sectors in the city of Jeddah, Saudi Arabia. MethodsThis cross-sectional study used a self-administered survey sent to GDPs and endodontic specialists in both government and private sectors in the city of Jeddah, Saudi Arabia. Responses were accepted from November 2019 till May 2020. The survey was randomly distributed to consenting participants. The results are presented using descriptive statistics. ResultsA total of 302 participants responded to the survey, with a 44% response rate. The majority of responses were from GDPs (54%), while 46% were from endodontic specialists. Regarding the workplace, 59% of respondents were public sector professionals, 25% were private sector professionals, and 16% were both public and private sector professionals. Around 30% of the respondents used sodium hypochlorite (NaOCI) as their primary irrigation solution during root canal treatment, with 52% using it at its full-strength concentration and 18% and 17% preferring to use it in combination with Ethylenediaminetetraacetic acid (EDTA) only or EDTA and saline, respectively. When asked to rank the reasons for choosing their irrigant of choice during therapy; antibacterial capability and tissue dissolution were the most crucial factors to 80% and 57% of participants, respectively. Half of the respondents irrigated the canal to 2 mm from the apex and 21% irrigated to 1 mm from the apex. Three-quarters of participants aimed to remove the smear layer during root canal treatment. Only 47% of respondents used adjuncts to irrigation, and 71% reported that their choice of irrigation solution would differ depending on whether the apex is open or closed. ConclusionMost respondents used full-strength NaOCI concentration as the main irrigation solution and routinely removed the smear layer during root canal treatment. Only 47% of respondents used irrigation adjuncts such as ultrasonics.

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Section: Discussionmentioning

confidence: 99%

Current Trends in Irrigation Solution and Adjunct Use During Endodontic Therapy Among Dental Professionals in Jeddah, Saudi Arabia: A Cross-Sectional Study

Alzamzami¹,

Alqurashi²,

Almansour³

et al. 2022

Cureus

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“…This is certainly in contrary with one of the required properties for a root canal irrigating material which has to be nontoxic. 5, 6 In addition to NaOCl, another irrigating material which frequently used is chlorhexidine gluconate (CHX). Chlorhexidine gluconate has antiseptic property and effectively controlling dental biofilms in patients with periodontal disease.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of 5% ethanol extracts of moringa oleifera leaf as an alternative of root canal irrigant to fibroblast BHK-21 cell culture

Nugroho¹,

Trilaksana²,

Natsir³

et al. 2021

J Dentomaxillofac Sci

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Objective:The purpose of this study was to determine the cytotoxicity of 5% ethanol extracts of Moringa oleifera leaf based on the percentage of fibroblast cell life after exposure to 5% ethanol extracts of Moringa oleifera leaf. Material and Methods: This study was an experimental laboratory with posttest only control group design. The extract was macerated using ethanol. Toxicity tested using the MTT Assay method. The fibroblast cells distributed in 96 well microplate were divided into 5 treatment groups. Group I as a negative control containing culture media, group II as a positive control containing cells in culture media, group III 5% ethanol extracts of Moringa leaf, group IV 2% chlorhexidine solution and group V 2.5% NaOCl solution. The percentage of cell life is calculated from the optical density value of the ELISA reader. Data were analyzed using the Kruskal Wallis test followed by the Post Hoc test using the Mann Whitney test. Results:The results showed the percentage of life of fibroblast cells after exposure to 5% ethanol extracts of Moringa oleifera leaf = 33.31%, 2.5% NaOCl = 28.89% and 2% chlorhexidine = 39.37% (p = 0.000, p < 0.05). Conclusion: 5% ethanol extracts of Moringa oleifera and 2% chlorhexidine were moderately toxic to fibroblast cells while 2.5% NaOCl was strongly toxic (p = 0.004, p <0.05).

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Comparative evaluation of antimicrobial activity of herbal extracts with 5.25% sodium hypochlorite against multispecies dentinal biofilm

Cited by 2 publications

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Current Trends in Irrigation Solution and Adjunct Use During Endodontic Therapy Among Dental Professionals in Jeddah, Saudi Arabia: A Cross-Sectional Study

Current Trends in Irrigation Solution and Adjunct Use During Endodontic Therapy Among Dental Professionals in Jeddah, Saudi Arabia: A Cross-Sectional Study

Cytotoxicity of 5% ethanol extracts of moringa oleifera leaf as an alternative of root canal irrigant to fibroblast BHK-21 cell culture

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