Comparability of Weight Loss Reporting After Gastric Bypass and Sleeve Gastrectomy Using BOLD Data 2008–2011

Sczepaniak, John P.; Owens, Milton L.; Shukla, Heena; Perlegos, John; Garner, William J.

doi:10.1007/s11695-014-1496-3

Cited by 45 publications

(27 citation statements)

References 21 publications

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“…Studies have demonstrated that even when looking at a single weight loss surgery such as GB, greater preoperative BMI is associated with decreased excess body weight loss [37], however with no significant difference in total body weight loss [38]. Our own analysis confirmed that weight loss differences at 6–24 months remained highly significant when adjusted for baseline BMI.…”

Section: Discussionsupporting

confidence: 71%

Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss

et al. 2016

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BackgroundThe purpose of the study was to compare weight loss, metabolic parameters, and postoperative complications in patients undergoing Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG).MethodsWe retrospectively studied 30-day postoperative complications as well as change in weight, blood pressure, cholesterol, hemoglobin, hemoglobin A1C, and creatinine from baseline to 2, 6, 12, and 24 months postoperatively in 383 patients undergoing GB and 336 patients undergoing SG at the University of Michigan from January 2008 to November 2013. For a study population which typically has high attrition rates, there were excellent follow-up rates (706/719 at 2 months, 566/719 at 6 months, 519/719 at 12 months, and 382/719 at 24 months).ResultsBaseline characteristics were similar in both groups except for higher weight and BMI in the SG group. The GB group experienced greater total body weight loss at 6, 12, and 24 months (41.9 vs. 34.6 kg at 24 months, p < 0.0001). Excess weight loss was 69.7 and 51.7 % following GB and SG respectively at 24 months (p < 0.0001). BP improved significantly in both groups. Surgical complication rates were greater after GB (10.1 vs. 3.5 %, p = 0.0007) with no significant difference in life-threatening or potentially life-threatening complications.ConclusionsWeight loss was greater following GB compared to SG at 2 years. The risk for surgical complications was greater following GB. Surgical intervention should be tailored to surgical risk, comorbidities, and desired weight loss.Electronic supplementary materialThe online version of this article (doi:10.1007/s11695-016-2265-2) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 71%

Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss

et al. 2016

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“…There is significant heterogeneity in previous studies as to whether baseline BMI is associated with better or worse outcomes depending on whether %EWL or %TWL is used [20], but in general %TWL is preferred as the outcome measure in long-term studies of bariatric surgery if one wishes to reduce variability based on initial BMI [21, 22]. Our data support a conclusion that higher BMI is associated with improved long-term %TWL following GB but a lower rate of achieving BMI < 30 kg/m 2 .…”

Section: Discussionmentioning

confidence: 99%

Milestone Weight Loss Goals (Weight Normalization and Remission of Obesity) after Gastric Bypass Surgery: Long-Term Results from the University of Michigan

et al. 2017

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Background Rates of weight normalization and obesity remission after Roux-en-Y gastric bypass (GB) are unknown. This study evaluated weight loss, rates of achieving body mass index (BMI) < 25 or 30 kg/m2, recidivism, and predictors of success following GB. Methods We retrospectively studied weight and BMI at baseline, 2 and 6 months, and annually at 1–7 years in 219 patients undergoing GB at the University of Michigan from January 2008 to November 2010. Results Follow-up was excellent for a population traditionally associated with high attrition rates with data availability of 157/219, 145/219, 144/219, 134/219, 123/219, 82/161, and 29/64 patients at 1–7 years respectively. Mean baseline BMI was 47.0 kg/m2. Weight normalization (BMI < 25 kg/m2) occurred in 2.3–6.8% of patients. More importantly, 47% of patients achieved remission of obesity (BMI < 30 kg/m2) at some time point and 24% (52/219) at the last observed time point. BMI < 30 kg/m2 was associated with a lower initial BMI and follow-up for more than 2 years. Conclusions Rates of weight normalization are low after GB, however a large number of patients achieved BMI < 30 kg/m2. While the percent total weight loss and excess weight loss are both quite high in the entire cohort and this is likely associated with significant health benefits, our results still underscore the need to address obesity with intensive clinical attention earlier in its course.

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“…The primary endpoint was percentage of total weight loss (%TWL) at 12 months. The weight loss indices among RYGB and SG patients within BOLD have been studied previously; %TWL was determined to be the most accurate and least influenced by initial weight and was suggested to be used for the expression of weight loss after surgery [24]. The secondary endpoints were disease resolution for DM, HTN, GERD, HLD, and OSA at 12 months, as well as 30-day postoperative safety.…”

Section: Methodsmentioning

confidence: 99%

Comparative effectiveness of Roux-en-Y gastric bypass and sleeve gastrectomy in super obese patients

Celio

Kasten

et al. 2016

Surg Endosc

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There are significant differences in comorbidity improvement and resolution as well as weight loss between RYGB and SG in the SO population. There was no difference in overall 30-day complications, but more RYGB patients required readmission and reoperation. However, RYGB was considerably more effective in controlling obesity-related comorbidities. Our results favor performance of RYGB in SO patients of appropriate risk.

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Comparability of Weight Loss Reporting After Gastric Bypass and Sleeve Gastrectomy Using BOLD Data 2008–2011

Abstract: For ease and accuracy of comparison, the percentage of initial body weight or percentage of total weight loss should be used for the expression of weight loss after surgery.

Cited by 45 publications

References 21 publications

Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss

Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss

Milestone Weight Loss Goals (Weight Normalization and Remission of Obesity) after Gastric Bypass Surgery: Long-Term Results from the University of Michigan

Comparative effectiveness of Roux-en-Y gastric bypass and sleeve gastrectomy in super obese patients

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