Comparative effectiveness of Roux-en-Y gastric bypass and sleeve gastrectomy in super obese patients

Celio, Adam C.; Wu, Qiang; Kasten, Kevin R.; Manwaring, Mark L.; Pories, Walter J.; Spaniolas, Konstantinos

doi:10.1007/s00464-016-4974-y

Cited by 52 publications

(24 citation statements)

References 34 publications

(39 reference statements)

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“…27 Likewise, 65% of patients with hypertension experienced a normalization ( 135/85 mm Hg) of their BP after surgery. The efficacy of SG as a therapeutic tool for diabetes mellitus in patients with obesity is still debated in the literature due to its assumed inferiority compared with other procedures 28 ; however, our experience supports the fact that even this intervention is particularly effective on the above-mentioned obesity-related comorbidity.…”

Section: Secondary Outcomessupporting

confidence: 53%

Sleeve Gastrectomy Efficacy on Metabolic and Cardiovascular Dysfunction With a Focus on the Role of Comorbidities

et al. 2017

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We evaluated the effects of sleeve gastrectomy (SG) on metabolic/cardiovascular parameters according to weight loss, visceral fat area (VFA), and homeostasis model assessment (HOMA)-insulin resistance index; we also assessed the influence of SG on comorbidities (diabetes/hypertension). At baseline and 10 to 12 months after SG, we assessed anthropometric and biochemical parameters, bioimpedentiometry, ultrasonographic VFA, liver steatosis, flow-mediated dilation, and echocardiography in 110 patients with obesity. We found that 23 (21%) patients had diabetes. Diabetic patients who normalized their glycated hemoglobin A (HbA) level experienced greater total weight loss (TWL), and the probability of normalizing HbA levels directly correlated with TWL. Diabetic patients experienced a greater improvement in systolic blood pressure, VFA, and high-density lipoprotein cholesterol than nondiabetics, while patients with hypertension experienced a greater improvement in VFA, triglycerides, HOMA, and HbA than nonhypertensive patients. The most important determinant of glucose control in diabetic patients was weight loss. Patients with diabetes and hypertension experienced a greater improvement in vascular and metabolic status after SG.

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Section: Secondary Outcomessupporting

confidence: 53%

Sleeve Gastrectomy Efficacy on Metabolic and Cardiovascular Dysfunction With a Focus on the Role of Comorbidities

et al. 2017

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“…Both procedures can result in up to a 30% loss in body weight 2,3 . Compared to VSG, RYGB leads to greater body weight loss [4][5][6][7] . Proposed mechanisms for the effectiveness of bariatric surgeries include: changes in levels of gut hormones (e.g.…”

Section: Introductionmentioning

confidence: 99%

Preoperative liking and wanting for sweet beverages as predictors of body weight loss after Roux-en-Y gastric bypass and sleeve gastrectomy

et al. 2019

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Background/objectives: Patients who receive Roux-en-Y gastric bypass (RYGB) lose more weight than those who receive vertical sleeve gastrectomy (VSG). RYGB and VSG alter hedonic responses to sweet flavor, but whether baseline differences in hedonic responses modulate weight loss after RYGB or VSG remains untested. Participants/methods: Male and female candidates (n=66) for RYGB or VSG were recruited and tested for their subjective liking and wanting ratings of sucrose solutions and flavored beverages sweetened with aspartame. Participants were classified by unsupervised hierarchical clustering for their liking and wanting ratings of sucrose and aspartame. Participant liking ratings were also used in a supervised classification using pre-established categories of liking ratings (liker, disliker, and inverted u-shape). Effects of categories obtained from unsupervised or supervised classification on body weight loss and their interaction with surgery type were analyzed separately at 3 and 12 months after surgery using linear models corrected for sex and age. Results: RYGB participants lost more body weight compared to VSG participants at 3 and 12 months after surgery (P < 0.001 for both time points). Unsupervised clustering analysis identified clusters corresponding to high and low wanting or liking ratings for sucrose or aspartame. RYGB participants in high-wanting clusters based on sucrose, but not aspartame, lost more weight than VSG at both 3 (P = 0.01) and 12 months (P = 0.03), yielding a significant cluster by surgery interaction. Categories based on supervised classification using liking ratings for sucrose or Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:

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“…[8] The robotic surgery has evolved as the newer paradigm in minimal access surgery[4] and it envisages the advantage of having a three-dimensional vision with articulating instruments. The surgeon sits on the console in the most comfortable way without stress on his shoulders and torque on arms even on most super obese patients.…”

Section: Discussionmentioning

confidence: 99%

Robotic Roux-en-Y gastric bypass: Our centre's technique with short-term experience

et al. 2017

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Comparative effectiveness of Roux-en-Y gastric bypass and sleeve gastrectomy in super obese patients

Cited by 52 publications

References 34 publications

Sleeve Gastrectomy Efficacy on Metabolic and Cardiovascular Dysfunction With a Focus on the Role of Comorbidities

Sleeve Gastrectomy Efficacy on Metabolic and Cardiovascular Dysfunction With a Focus on the Role of Comorbidities

Preoperative liking and wanting for sweet beverages as predictors of body weight loss after Roux-en-Y gastric bypass and sleeve gastrectomy

Robotic Roux-en-Y gastric bypass: Our centre's technique with short-term experience

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