Milestone Weight Loss Goals (Weight Normalization and Remission of Obesity) after Gastric Bypass Surgery: Long-Term Results from the University of Michigan

Abstract

Background Rates of weight normalization and obesity remission after Roux-en-Y gastric bypass (GB) are unknown. This study evaluated weight loss, rates of achieving body mass index (BMI) < 25 or 30 kg/m2, recidivism, and predictors of success following GB. Methods We retrospectively studied weight and BMI at baseline, 2 and 6 months, and annually at 1–7 years in 219 patients undergoing GB at the University of Michigan from January 2008 to November 2010. Results Follow-up was excellent for a population traditionally associated with high attrition rates with data availability of 157/219, 145/219, 144/219, 134/219, 123/219, 82/161, and 29/64 patients at 1–7 years respectively. Mean baseline BMI was 47.0 kg/m2. Weight normalization (BMI < 25 kg/m2) occurred in 2.3–6.8% of patients. More importantly, 47% of patients achieved remission of obesity (BMI < 30 kg/m2) at some time point and 24% (52/219) at the last observed time point. BMI < 30 kg/m2 was associated with a lower initial BMI and follow-up for more than 2 years. Conclusions Rates of weight normalization are low after GB, however a large number of patients achieved BMI < 30 kg/m2. While the percent total weight loss and excess weight loss are both quite high in the entire cohort and this is likely associated with significant health benefits, our results still underscore the need to address obesity with intensive clinical attention earlier in its course.

Women in larger bodies’ experiences with contraception: a scoping review

“…However, among studies that reported postoperative BMI, mean or median BMIs were all above ‘normal’, and often ≥ 30, indicating that many participants would still be considered women in larger bodies [ 50 , 52 , 54 , 55 , 57 , 58 , 61 ]. This is consistent with previous research suggesting that the majority of patients do not achieve ‘normal’ BMI after bariatric surgery [ 85 , 86 ]. Nonetheless, future research should address weight loss and compare women in larger bodies within and across BMI categories to better understand how experiences with contraception may differ by body size, shape, or BMI classification.…”

Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study

“…We also report number of patients with more than 10 kg weight regain between 1 and 5 years16 and number of patients whose %EBMIL was below 50 at 5 years 17. Furthermore, we report number of patients whose BMI was below 30 kg/m 2 5 years after SG 18…”

Functional Magnetic Resonance Imaging (fMRI) of Neural Responses to Visual and Auditory Food Stimuli Pre and Post Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG)

“…LED cues in reward areas in both surgery groups. Since nonsurgical weight loss is often followed by weight regain, we expected that WL would show increased brain responsivity in reward areas vs. the surgery groups (Lager CJ et al, 2017;Sepulveda M et al, 2017). We also expected to see differences in connectivity between the RYGB and SG vs. WL and NT groups, given evidence that individuals with obesity have altered brain networks (Gupta A et al, 2015).…”