Co-existence of micronutrient deficiencies in hospitalized children with severe malnutrition treated according to the WHO protocol

Caminha, Maria de Fátima Costa; Figueira, Manoela Almeida Santos da; Falbo, Ana Rodrigues; Amorim, Roberta de Araújo de Corrêa; Gallindo, Thomaz Caminha; Filho, Malaquias Batista

doi:10.1258/td.2011.100140

Cited by 3 publications

(2 citation statements)

References 3 publications

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“…43 However, it was lower than studies done in Ethiopia (61% in stunted, 64.3% in underweighted, and 68.2% in wasted children), 17 India (84%, 44 90%, 45 91%, 9 and 95% 22 ), and Brazil (88%). 46 In contrast, it was higher than study conducted in Ethiopia (41.43%). 47 The possible explanation for the difference could be attributed to variations in the socio-demographic characteristics, sample size, and study design.…”

Section: Discussionmentioning

confidence: 67%

<p>Hematological Abnormalities and Associated Factors Among Undernourished Under-Five Children Attending University of Gondar Specialized Referral Hospital, Northwest Ethiopia</p>

Getawa

Getaneh

Melku

2020

JBM

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Introduction The hematopoietic system is one of the systems which can be affected by malnutrition, leading to impaired production of all blood cell lines. Undernourished children with hematological abnormalities like anemia are at higher risk of mortality. Therefore, this study aimed at determining the magnitude and associated factors of hematological abnormalities among undernourished under-five children attending at the University of Gondar Specialized Referral Hospital, Northwest Ethiopia. Methods and Materials An institution-based cross-sectional study was conducted on a total of 251 undernourished under-five children at University of Gondar Specialized Referral Hospital from January to May 2020. A convenient sampling technique was employed to select study participants. Data were collected using a pretested structured questionnaire. Blood samples were collected for complete blood count which were determined by Sysmex KX-21N analyzer. Stool sample was processed via direct wet mount. Thin and thick blood films were examined to assess malaria parasite. The data were entered to EpiData version 4.6.0.0 and analyzed using SPSS version 23 software. Bi-variable and multi-variable binary logistic regression model were fitted to identify factors associated with hematological abnormalities. A p-value <0.05 in the multivariable analysis was considered as statistically significant. Results The overall magnitude of anemia, leukocytosis, thrombocytosis, thrombocytopenia, and leukopenia was 53.4%, 26.7%, 23.9%, 8%, and 2.8%, respectively. Being male, age 6–23 months, high birth order, intestinal parasite infection, edema, not eating vegetables and fruits, and paternal occupation were found to be associated with anemia. Only the age of a child was associated with leukocytosis in undernourished children. Conclusion The current study demonstrated the predominant existence of anemia, leukocytosis, and thrombocytosis among undernourished under-five children. Therefore, early diagnosis, monitoring and setting intervention strategies for anemia especially among children under two years old are required to prevent further complication.

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Section: Discussionmentioning

confidence: 67%

<p>Hematological Abnormalities and Associated Factors Among Undernourished Under-Five Children Attending University of Gondar Specialized Referral Hospital, Northwest Ethiopia</p>

Getawa

Getaneh

Melku

2020

JBM

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“…In low income countries, severe acute malnutrition (SAM) remains a major killer of children under five years of age. Anemia is common between severely malnourished children [1]- [3] and severe anemia is a medical emergency. Currently, for inpatient treatment, it is strongly recommended not to add iron during treatment initial phase (stabilization phase).…”

Section: Introductionmentioning

confidence: 99%

Impact of Anemia on Mortality and Nutritional Recovery among Hospitalized Severely Malnourished Children in Burkina Faso

Savadogo¹,

Zoetaba²,

Ilboudo³

et al. 2014

OJPed

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This study aimed to analyze the impact of anemia on mortality rate and nutritional recovery, during severely malnourished inpatient treatment. Material and Methods: This was a retrospective cohort study conducted from data of severely malnourished children hospitalized at a feeding the rapeutic center. Pearson's Chi square test, General linear model, Mortality relatives risks, Kaplan-Meir survival curves have been used. Results: At admission, 85.3% of included malnourished children had anemia (Hb ≤ 11 g/dl) and 10.6% severe anemic (Hb < 6 g/dl). Mortality rate did not differed significantly from severely malnourished children with anemia (12.4%) and without anemia (22.2%), p = 0.12. Kaplan Meir survival curves did not differed significantly between the two groups, (p Log Rank = 0.11). From admission to discharge, anthropometric Z-scores means evolution did not differed significantly between severely malnourished children with and without anemia at admission. But anthropometric Z-scores means evolution differed significantly within each group's subjects: WHZ (between groups: p = 0.74; within subjects: p < 0.001), and WAZ (between groups: p = 0.54; within subjects: p < 0.001). Conclusion: With a strong respect of current recommendation of anemia treatment of inpatient severely malnutrition management, there is no

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Hematologic and Bone Marrow Changes in Children with Protein-Energy Malnutrition

Özkale

Sipahi

2013

Pediatric Hematology and Oncology

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Co-existence of micronutrient deficiencies in hospitalized children with severe malnutrition treated according to the WHO protocol

Cited by 3 publications

References 3 publications

<p>Hematological Abnormalities and Associated Factors Among Undernourished Under-Five Children Attending University of Gondar Specialized Referral Hospital, Northwest Ethiopia</p>

<p>Hematological Abnormalities and Associated Factors Among Undernourished Under-Five Children Attending University of Gondar Specialized Referral Hospital, Northwest Ethiopia</p>

Impact of Anemia on Mortality and Nutritional Recovery among Hospitalized Severely Malnourished Children in Burkina Faso

Hematologic and Bone Marrow Changes in Children with Protein-Energy Malnutrition

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