Clinicopathological study of adult malignant renal tumours in Kashmir

Bilal, Sheikh; Farooq, Summyia; Beigh, Ambreen; Reshi, Ruby; Beigh, Arshi; Manzoor, Farzana

doi:10.18535/ijmsci/v4i2.14

Cited by 3 publications

(4 citation statements)

References 21 publications

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“…The majority of our patients were ISUP Grade 1 and 2 (73.68%) followed by Grade 3 (14.03%) nearly similar to Bilal et al, [23] while Patard et al, [26] show Grade 2 (36.7%) followed by Grade 3 (34.4%). The Grade 3 cases were higher in Patard et al, in comparison of our result.…”

Section: Discussionsupporting

confidence: 87%

Histopathological Evaluation of Malignant Adult Renal Tumors-A Study of Specialized Tertiary Care Center

Parvez¹,

Islam²,

Tapan³

et al. 2023

Glob Acad J Med Sci

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Background: According to the recent World Health Organization (WHO), renal cell carcinomas (RCCs) that primarily affect adults and 2.2% of all new malignancies and 1.8% of all cancer deaths. Majority of the cases, the diagnosis of RCCs and its subtype can be based on histomorphological evaluation. Accurate pathological classification along with staging and grading of the tumor are necessary for prognosis and various therapeutic options. Materials and Methods: It was a retrospective observational study. This study conducted in histopathology department of the Center for Kidney Disease & urology (CKD & Urology) Hospital, Dhaka, Bangladesh. The study period was eight month from February 2021 to September 2021. The specimens were both partial and total nephrectomy sample of more than 38 years of aged patients. Results: Total 62 nephrectomy specimens were received. Fifty seven (57) cases were malignant tumor and five cases were benign lesions. Majority of malignant tumor consisting of clear cell type renal cell carcinoma 37 (64.91%), followed by papillary type 12 (21.05%), Chromophobe (8.77%), two cases (3.5%) were sarcomatoid cell type and one case (1.75%) of Multiloculated Cystic Renal Neoplasm was noted. Renal cell carcinoma was seen in age range of 38 to 78years with 32 (56.14%) patients more than 50 years of age. Total 42 (73.68%) cases were ISUP Grade 1 and 2 and majority cases were (66.66%) presented at AJCC stage (pT2). Conclusion: In conclusion we observed significant increased clear cell type renal cancer in our institution based population. There was similar male to female ratio, mean tumor size as well as Grade 1, 2 and Stage pT 2 as compared to other studies.

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Section: Discussionsupporting

confidence: 87%

Histopathological Evaluation of Malignant Adult Renal Tumors-A Study of Specialized Tertiary Care Center

Parvez¹,

Islam²,

Tapan³

et al. 2023

Glob Acad J Med Sci

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“…Renal cell carcinoma (RCC) accounts for 1 to 3% of all visceral cancers and 85% of renal cancers. 2 There was a male predominance among the neoplastic conditions similar to Suryawanshi et al, 1 Ghalayini et al, 6 Anitha Padmanabhan et al 3 and Sheikh Bilal et al 14 Majority of tumours were noted in 41-60 years age range (31 cases out of total 64 neoplastic conditions) similar to studies done by Anitha Padmanabhan et al, 3 Suryawanshi et al 1 and Sheikh Bilal et al 14 Majority of tumours involved left kidney similar to studies done by Swarnlata Ajmera et al 10 and Sheikh Bilal et al 14 Clear cell renal cell carcinoma was the commonest tumor constituting 32 cases out of 64 neoplastic conditions (50%) reported during our study period. Similarly highest incidence of clear cell RCC was reported in studies done by Rafique M' et al 7 Clear cell RCC was common in males and involved left kidney more often in this study.…”

Section: Discussionmentioning

confidence: 87%

Histopathology of nephrectomy specimens: A ten year south Indian tertiary hospital based study

2020

JDPO

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Introduction: Nephrectomies are an integral part of urological practice and a wide range of renal diseases are seen on histopathological examination of nephrectomy specimens. Aim: This study was conducted to evaluate the neoplastic and non neoplastic conditions encountered in nephrectomy specimens that were received in our department over a ten year period and compare it with other studies. Materials and Methods: A hospital-based ten year retrospective study of all nephrectomy specimens received in the department of Pathology. Results: A total of 177 nephrectomy specimens were studied. 54.3% cases were male patients with peak during 5 th-6 th decade. 63.8% cases were non neoplastic lesions and 36.2% neoplastic lesions. Conclusion: Inflammatory causes more commonly required a nephrectomy in this study. The commonest indication for nephrectomy was chronic pyelonephritis followed by clear cell renal cell carcinoma.

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“…An estimated 50-60 % tumours in the USA are incidentally detected asymptomatic lesions picked up on diagnostic imaging. As a result, the masses tend to be much smaller and tend to be more localised in the west (Bilal et al, 2017).…”

Section: Clinical Presentation By Patients Of Renal Tumoursmentioning

confidence: 99%

“…Worldwide, the renal tumour is the 13th most common malignancy and accounts for approximately 2-3% of adult malignancies and 80-85 % of malignant kidney tumours which are having 2% of overall can-cer mortality (Ferlay et al, 2010;Bilal et al, 2017). Thus the surgical removal of these tumours is the mainstay of treatment of localised renal tumours, and it also provides survival bene it in the setting of metastatic disease (Pradhan et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Clinicopathological study of renal tumours in surgically excised specimens

Warhate¹,

Jagtap²,

Kanetkar³

2020

ijrps

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A study on Clinicopathological Study Of Renal Tumours In Surgically Excised Specimens was conducted for two years from June 2016 to May 2018. The study was on twenty-eight surgically excised specimens of renal tumours in the Department of Pathology of Krishna Institute of Medical Sciences at Karad District in Satara, Maharastra, India. The observed results stood as 75% of Radical Nephrectomy, 17.85% of renal biopsies and partial Nephrectomy in 7.14% cases. The reading revealed 28.5% of cases, that is, a maximum number were found in their 6th decade of life. The rest of the cases, 21.42% were either septuagenarian or quadragenarian. The male preponderance was noted with Male: Female ratio 2.5:1. Out of 28 cases of renal tumours, 50% of cases had flank pain, 28.57% cases with flank pain associated with hematuria in A maximum number of instances had issues that were involving the left-sided kidney. The most common site for tumour involvement was upper pole comprising of 35.71% followed by the lower pole in 28.57% of cases. In a maximum number of instances, grossly the size of tumour ranged from 0-4 cm. Out of all malignant tumours, Renal Cell Carcinoma-RCC was the most common tumour comprising (75%). The majority (42.10%) of renal cell carcinomas were of Fuhrman nuclear grade II. Majority of cases (56.5%) were at TNM stage I. A detailed histopathology examination and routine H and E staining help - to diagnose accurately and to determine the various histological type, subtype. It also helps to evaluate other histopathological determinants. The clinical results shifts as per the histologic subtypes.

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Clinicopathological study of adult malignant renal tumours in Kashmir

Abstract: A wide variety of both benign and Malignant tumours arise from different components of the renal parenchyma, notably tubular epithelium[1-4].Renal tumours comprise a diverse spectrum of neoplastic lesions with patterns that are relatively distinct for children and adults[1-4].

Cited by 3 publications

References 21 publications

Histopathological Evaluation of Malignant Adult Renal Tumors-A Study of Specialized Tertiary Care Center

Histopathological Evaluation of Malignant Adult Renal Tumors-A Study of Specialized Tertiary Care Center

Histopathology of nephrectomy specimens: A ten year south Indian tertiary hospital based study

Clinicopathological study of renal tumours in surgically excised specimens

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