Clinical results of hydrogel lens implantation

Abstract

Polymethylmethacrylate has proven to be a useful intraocular lens (IOL) implant material and remains the most widely used material for the fabrication of IOLs. Complications, however, from IOL implantation still occur. A hydrogel lens has been designed for posterior chamber placement. A clinical study from August 1983 to June 1985 was undertaken to determine the safety and efficacy of this new lens manufactured from 38% poly HEMA. The noninflammatory postoperative complications were limited to lens decentration and opacification of the lens capsule. Three cases of posterior capsule opacification required YAG laser capsulotomy. Laser capsulotomy is feasible and the lens appeared to be more resistant to damage from the YAG laser than polymethylmethacrylate lenses. In general, the material appeared to be well tolerated and there have been no cases of persistent iritis or clinically detectable cystoid macular edema. If the visual acuity outcome by age decade for all patients irrespective of follow-up time is considered, 92% of patients achieved 20/40 or better corrected visual acuity.

Comparison of the Long-term Clinical Results of Hydrophilic and Hydrophobic Acrylic Intraocular Lenses

“…Several studies suggested that the incidence of PCO was lower in eyes implanted with IOLs made from acryl than with those made from PMMA and silicone polymer. 3,8,9,11,12 Sundelin et al 2 reported a 6.2% incidence rate of PCO during a 3-year follow-up examination. Ram et al 3 reported a 6.5% incidence rate of PCO and that Nd:YAG laser capsulotomy was performed to remove the opacity.…”

“…Many studies have dealt with hydrophilic and hydrophobic acrylic IOLs, showing high biocompatibility and low incidence of PCO, but fewer studies have compared the clinical consequences of these two lenses on a long-term basis. [4][5][6][7][8][9][10] The present study aimed to investigate the incidence of PCO and refractive errors of hydrophilic (ACR6D, Corneal ® ) and hydrophobic (MA60BM, AcrySof ® ) foldable acrylic IOLs over a three-year follow-up period after phacoemulsification surgery.…”

Long-Term Results with logel lOLs

“…More recently these materials have been investigated by Barrett et al [20,21], Blumenthal et al [22] and Menapace etal. [7,10,12], Despite their biocompat ibility and the good functional results, hydro gel lenses have not been well accepted.…”

“…The first model (Iogel PC-12) had an over all length of 12.0 mm and it was implanted both in the ciliary sulcus [6,20] and in the capsular bag [23]. A 12-mm lens placed in the ciliary sulcus is of inadequate length.…”

Antimicrobial hydrogels based on 2-hydroxyethyl methacrylate and itaconic acid containing silver(I) ion

“…2-Hydroxyethyl methacrylate (HEMA) was chosen as the main component of the hydrogel network because this functional monomer and its copolymers exhibit excellent biocompatibility, blood compatibility, cytotoxicity, cell compatibility and low thrombogenicity [14]. It is a commercially important monomer that is widely used in the manufacture of soft contact lenses and intraocular lenses [15,16]. Itaconic acid (IA) is very hydrophilic and is expected to show high biocompatibility because of its natural source.…”